Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,657 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 11, 2026.

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3,655 clinical trials

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Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

for Hematologic Neoplasms

2 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 85·Accepts healthy volunteers

Code: NCT04959175·Phase 1, Phase 2·Recruiting

Apply to this trial

Innovations in Genicular Outcomes Registry

for Knee Osteoarthritis

19 locations incl. Phoenix

Sponsor: Pacira Pharmaceuticals, Inc

Sex: All·Age: All ages

Code: NCT05495334·Recruiting

Apply to this trial

RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

for Ischemic Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 90

Code: NCT04897334·Recruiting

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SARS-CoV-2 CTLS for Mild to Moderate COVID-19 Disease

for Covid19

4 locations incl. Valhalla

Sponsor: New York Medical College

Sex: All·Age: 18 - 65

Code: NCT04896606·Phase 1, Phase 2·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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Mechanistic Interventions and Neuroscience of Dissociation

for Dissociation

2 locations incl. Atlanta

Sponsor: Emory University

Sex: All·Age: 18 - 65

Code: NCT04670640·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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Helix Research Network

for Genetic Predisposition to Disease

14 locations incl. Fort Wayne

Sponsor: Helix, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06057181·Recruiting

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Post Market Clinical Follow-up Study on TVT ABBREVO® Continence System

for Stress Urinary Incontinence

1 location in North Wales

Sponsor: Ethicon, Inc.

Sex: Female·Age: 21+

Code: NCT04829357·Recruiting

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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

11 locations incl. Washington D.C.

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting

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Point-of-Care Ultrasound in Predicting Adverse Outcomes in Emergency Department Patients With Acute Pulmonary Embolism

for Pulmonary Embolism

1 location in York

Sponsor: WellSpan Health

Sex: All·Age: 18+

Code: NCT05050617·Recruiting

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TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

for Hematopoietic Stem Cell Transplant (HSCT)

9 locations incl. San Francisco

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 24

Code: NCT04098445·Recruiting

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Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

for Advanced Solid Tumor

6 locations incl. Santa Monica

Sponsor: Senhwa Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04890613·Phase 1·Recruiting

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

14 locations incl. Birmingham

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting

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Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

28 locations incl. Laguna Hills

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

33 locations incl. Birmingham

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting

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Zinc Oxide Versus Petrolatum Following Skin Surgery

for Surgical Incision

1 location in Pittsburgh, PA

Sponsor: Melissa Pugliano-Mauro

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03561376·EARLY_Phase 1·Recruiting

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

10 locations incl. Aurora

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

4 locations incl. San Francisco

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting

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Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for Anatomic Stage 0 Breast Cancer AJCC v8

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 40+

Code: NCT04959474·Recruiting

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Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

10 locations incl. Little Rock

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting

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A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection

for Adenovirus Infections

11 locations incl. Los Angeles

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT04706923·Phase 2·Recruiting

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Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

for Retinopathy of Prematurity

2 locations incl. Durham

Sponsor: Duke University

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04995341·Recruiting

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Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

A Study Evaluating Oral Eluxadoline Administered to Pediatric Participants With Irritable Bowel Syndrome With Diarrhea (IBS-D)

for Irritable Bowel Syndrome

6 locations incl. Corona

Sponsor: AbbVie

Sex: All·Age: 6 - 17

Code: NCT04880876·Phase 3·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

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X-linked Moesin Associated Immunodeficiency

for Immune Deficiency

3 locations incl. Bethesda

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Sex: Male·Age: 4 - 80

Code: NCT06278337·Recruiting

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Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

15 locations incl. Huntington Beach

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting

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Continuous Glucose Monitoring in At-Risk Newborns

for Neonatal Hypoglycemia

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 1 Minute - 2 Weeks

Code: NCT04386005·Recruiting

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Outpatient Treatment With Anti-Coronavirus Immunoglobulin

for COVID

22 locations incl. Tucson

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT04910269·Phase 3·Recruiting

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IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

Fear of Recurrence and Stopping Immunotherapy

for Cognitive Behavioral Therapy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 21+

Code: NCT04761328·Recruiting

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Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

for Brain Structure

2 locations incl. Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04856410·Enrolling By Invitation

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

for Adult Spinal Deformity

12 locations incl. Phoenix

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04885244·Recruiting

Apply to this trial

Zimmer Biomet Shoulder Arthroplasty PMCF

for Shoulder Fractures

12 locations incl. Irvine

Sponsor: Zimmer Biomet

Sex: All·Age: 20+

Code: NCT04984291·Recruiting

Apply to this trial