Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,659 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 4, 2026.

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3,659 clinical trials

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Centering Autistic Perspectives in Behavioral Intervention Discussions

for Autism

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07165522·Not Yet Recruiting

Biomarker Feedback Intervention

for High Risk Drinking

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18 - 23·Accepts healthy volunteers

Code: NCT07307326·Not Yet Recruiting

A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

12 locations incl. Little Rock

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting

Apply to this trial

Endotype DIrected Treatment for OSA in Down Syndrome

for Obstructive Sleep Apnea (OSA)

5 locations incl. Tucson

Sponsor: University of Arizona

Sex: All·Age: 6+

Code: NCT07280468·Phase 4·Recruiting

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Flourish in Schools Pilot Study

for Psychological Distress

2 locations incl. Bay Village

Sponsor: Candice Biernesser

Sex: All·Age: 11 - 21

Code: NCT07506525·Recruiting

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A Study for CTC Expression and cfDNA/RNA Assessment in Metastatic Breast Cancer Patients

for Metastatic Breast Cancer (MBC)

1 location in Pittsburgh

Sponsor: Menarini Silicon Biosystems, INC

Sex: All·Age: 18+

Code: NCT06833853·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

Drug: Nivolumab

34 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221149·Phase 2, Phase 3·Recruiting

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Supraglottic Airway for Resuscitation in Preemies

for Respiratory Failure

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 1 Day

Code: NCT07419438·Recruiting

Apply to this trial

SPACE for Youth With Chronic Pain

for Chronic Pain

2 locations incl. Palo Alto

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 10 - 17

Code: NCT07425691·Recruiting

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A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

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A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder

for Muscle-invasive Bladder Cancer

5 locations incl. Little Rock

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07475806·Phase 2·Recruiting

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A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea

for Functional Hypothalamic Amenorrhea (FHA)

6 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18 - 40

Code: NCT07235917·Phase 2·Recruiting

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A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes

for Type 1 Diabetes

Drug: Adalimumab

11 locations incl. San Francisco

Sponsor: City of Hope Medical Center

Sex: All·Age: 9 - 20

Code: NCT07061574·Phase 1, Phase 2·Recruiting

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Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar

for Colorectal Cancer

4 locations incl. Louisville

Sponsor: Exero Medical Ltd.

Sex: All·Age: 21+

Code: NCT07337590·Recruiting

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Allogeneic HSCT With Low-Dose Post-Transplant Cyclophosphamide for GVHD Prevention

for Graft-versus-Host Disease (GVHD)

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06926595·Phase 2·Recruiting

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Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization

for Schizophrenia Disorder

5 locations incl. Pittsburgh

Sponsor: Stanford University

Sex: All·Age: 18 - 65

Code: NCT07130500·Enrolling By Invitation

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

12 locations incl. Huntington Beach

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting

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A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure

for Lyme Disease

19 locations incl. Pikesville

Sponsor: Tarsus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07562087·Phase 2·Recruiting

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Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

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Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants

for ADHD - Attention Deficit Disorder With Hyperactivity

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 7 - 12

Code: NCT06871488·Phase 4·Recruiting

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

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A Study of Nipocalimab in Adults With Moderate to Severe Systemic Lupus Erythematosus

for Lupus Erythematosus, Systemic

Drug: Nipocalimab

24 locations incl. Beverly Hills

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 75

Code: NCT07438496·Phase 3·Recruiting

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A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

1 location in Philadelphia

Sponsor: BicycleTx Limited

Sex: All·Age: 18+

Code: NCT07450859·Phase 2·Recruiting

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A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for NSCLC Adenocarcinoma

10 locations incl. Orlando

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07277413·Phase 1·Recruiting

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Urinary Titin Biomarker in DMD

for Duchenne Muscular Dystrophy (DMD)

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: Male·Age: 2 - 10·Accepts healthy volunteers

Code: NCT07332013·Recruiting

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Mapping LIFU Responses Using iEEG Recordings

for Low Intensity Focussed Ultrasound

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 21 - 75

Code: NCT07518927·Enrolling By Invitation

Rezdiffra Pregnancy and Lactation Registry

for MASH - Metabolic Dysfunction-Associated Steatohepatitis

1 location in West Conshohocken

Sponsor: Madrigal Pharmaceuticals, Inc.

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT07541469·Recruiting

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OCD LIFU Target Engagement

for Obsessive Compulsive Disorder (OCD)

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 60

Code: NCT07558148·Recruiting

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Nature in Harmony: Music and Nature-based Self-care for Individuals With Acquired Brain Injuries and Their Care Partners

for Acquired Brain Injury (Including Stroke)

1 location in Pittsburgh

Sponsor: Duquesne University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07568301·Enrolling By Invitation

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

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A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

6 locations incl. Irvine

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07227025·Phase 1, Phase 2·Recruiting

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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

for Pulmonary Hypertension Associated With HFpEF

18 locations incl. Alexander City

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07288398·Phase 3·Recruiting

Apply to this trial

Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension

for Hypertension, Pregnancy Induced

3 locations incl. New York

Sponsor: Jennifer Lewey, MD, MPH

Sex: Female·Age: 18+

Code: NCT07209254·Recruiting

Apply to this trial

Upper Airway Ultrasound to Predict Difficult Laryngoscopy in Neonates and Infants

for Neonates

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 365 Days·Accepts healthy volunteers

Code: NCT07444528·Enrolling By Invitation

MyStroke for Stroke Survivors and Caregivers

for Stroke, Acute

5 locations incl. Lancaster

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06442631·Not Yet Recruiting

Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: Ramon Diaz-Arrastia

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06963775·Not Yet Recruiting

Potatoes as a Strategy to Improve Diet Quality in Young Children

for Dietary Intake

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT07358390·Enrolling By Invitation

Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners

for Literacy

1 location in State College

Sponsor: Penn State University

Sex: All·Age: 5 - 12

Code: NCT07384156·Phase 1, Phase 2·Not Yet Recruiting

DVT Evaluation Using POCUS for Diagnosis and Treatment

for Deep Venous Thromboses

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT07400510·Enrolling By Invitation

The Improving Sleep in African American Couples Study (ISAAC)

for Obstructive Sleep Apnea (OSA)

2 locations incl. Cleveland

Sponsor: MetroHealth Medical Center

Sex: All·Age: 30+

Code: NCT07447284·Not Yet Recruiting