Paid Clinical Trials in Pennsylvania

Pennsylvania has 3,659 paid clinical trials enrolling now across cities including Philadelphia, Pittsburgh and Hershey. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Pennsylvania include Penn Medicine, Children's Hospital of Philadelphia and UPMC, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 4, 2026.

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3,659 clinical trials

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Locating Biomarkers in OCD Through Behavioral Tasks

for OCD

3 locations incl. Pittsburgh

Sponsor: Baylor College of Medicine

Sex: All·Age: 18 - 65

Code: NCT03313622·Not Yet Recruiting

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

for Systemic Lupus Erythematosus

1 location in Philadelphia

Sponsor: Stephan Grupp MD PhD

Sex: All·Age: 8 - 25

Code: NCT05029336·Phase 2·Recruiting

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Hypoxic Red Blood Cells in Sickle Cell Anemia

for Sickle Cell Anaemia

6 locations incl. Farmington

Sponsor: Hemanext

Sex: All·Age: 7+

Code: NCT06743113·Not Yet Recruiting

Thrive Initiative Parent-Education Programming Study

for Child Maltreatment

1 location in University Park

Sponsor: Penn State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06823518·Recruiting

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Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease

for Malignant Pleural Effusion

1 location in Pittsburgh

Sponsor: David Bartlett, MD

Sex: All·Age: 18 - 79

Code: NCT07192900·Phase 1·Recruiting

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From Kitchen to Clinic

for Pediatric Cancer

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 5 - 21

Code: NCT07454902·Not Yet Recruiting

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

12 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Not Yet Recruiting

This is a Single Center, Open-label Prospective Study to Evaluate the Effect of Xiidra® (Lifitegrast Ophthalmic Solution 5.0%) on Tear Film Biomarkers in Dry Eye

for Ocular Surface Disease

1 location in Sewickley

Sponsor: Pittsburgh Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07490535·Phase 4·Not Yet Recruiting

Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

8 locations incl. Duarte

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting

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HeartBeam ECG Registry

for Atrial Fibrillation

1 location in Pittsburgh

Sponsor: HeartBeam, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07501299·Not Yet Recruiting

Virtual Reality in End Stage Kidney Disease

for End Stage Kidney Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: All ages

Code: NCT06356168·Recruiting

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Phase II Study of Platinum/Etoposide Plus Ivonescimab for Extensive-Stage Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Cancer

Drug: Ivonescimab

6 locations incl. New Brunswick

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT07057791·Phase 2·Recruiting

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Spinal Cord Stimulation for Children With Cerebral Palsy

for Cerebral Palsy

1 location in Pittsburgh

Sponsor: Martin Piazza

Sex: All·Age: 5 - 17·Accepts healthy volunteers

Code: NCT07516067·Recruiting

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Remimazolam NeuroImaging

for Anesthesia

1 location in Pittsburgh

Sponsor: Keith M Vogt

Sex: All·Age: 18 - 59·Accepts healthy volunteers

Code: NCT07290205·EARLY_Phase 1·Recruiting

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Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships

for HIV

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07246057·Recruiting

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Neuralert Stroke Monitor Trial

for Surgery

1 location in Philadelphia

Sponsor: Neuralert Technologies LLC

Sex: All·Age: 22+

Code: NCT07362303·Recruiting

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Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for Type 1 Diabetes Mellitus

2 locations incl. Pittsburgh

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 8 - 45

Code: NCT07142252·Phase 2·Recruiting

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Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIV

for HIV

7 locations incl. Atlanta

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390474·Phase 1·Recruiting

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How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses

for Cardiometabolic Health

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07121010·Recruiting

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Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

for Breast Neoplasms

39 locations incl. Birmingham

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07214532·Recruiting

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A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

for Huntington Disease

8 locations incl. Englewood

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 21 - 70

Code: NCT07326709·Phase 3·Recruiting

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Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

for Chronic Kidney Disease 5D

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 60+

Code: NCT07446296·Recruiting

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Little Cigar Oxidants

for Tobacco Use

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 65

Code: NCT06310187·Recruiting

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Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

for Parkinsons Disease (PD)

1 location in Pittsburgh

Sponsor: Pravat Mandal

Sex: All·Age: 50 - 80

Code: NCT07064005·Phase 1·Recruiting

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Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders

for Eating Disorders

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 12 - 26

Code: NCT07237607·Recruiting

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Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction - Coronary Computed Tomography Angiography Trial

for Cardiovascular Disease

Drug: Olpasiran

6 locations incl. Bridgeport

Sponsor: Amgen

Sex: All·Age: 35 - 80

Code: NCT07293260·Phase 3·Recruiting

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PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

for Proteinuric Kidney Diseases

25 locations incl. Huntsville

Sponsor: Boehringer Ingelheim

Sex: All·Age: 12+

Code: NCT07355296·Phase 2·Recruiting

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Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy

for Soft Tissue Sarcoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07436364·EARLY_Phase 1·Recruiting

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First Time in Human (FTIH) Study to Investigate the Safety and Preliminary Activity of GSK5533524 Alone or in Combination in Adult Participants With Advanced Solid Tumors

for Neoplasms

2 locations incl. Philadelphia

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07438782·Phase 1·Recruiting

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Romosozumab Effects on Bone Density, Muscle Mass, and Spine Surgery Outcomes

for Osteoporosis, Post-menopausal

1 location in Pittsburgh

Sponsor: Nitin Agarwal

Sex: Female·Age: 65+

Code: NCT06973109·Phase 2·Not Yet Recruiting

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

for Osteoporotic Fractures

2 locations incl. San Francisco

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 50+

Code: NCT07027306·Recruiting

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

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Pembrolizumab Plus Ultrasound-Induced Microbubble Cavitation in Head and Neck Cancer

for Head and Neck Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07501650·Phase 1·Recruiting

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

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Feasibility of Intradialytic Monitoring During CKRT

for Acute Kidney Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07428395·Enrolling By Invitation

Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

for Urge Urinary Incontinence

4 locations incl. Homewood

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT07456865·Recruiting

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The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

15 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

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A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

for Obesity or Overweight

Drug: Enicepatide

25 locations incl. Anniston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07351045·Phase 3·Recruiting

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

12 locations incl. Santa Monica

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting

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Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer

for Prostate Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Male·Age: 18+

Code: NCT06024772·Phase 3·Not Yet Recruiting