Neurology Clinical Trials in Philadelphia, PA

As of August 2026, 79 paid clinical trials are recruiting for Neurology in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

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79 clinical trials for Neurology

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Philadelphia, Hershey +45 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

Apply to this trial

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Philadelphia, Pittsburgh +89 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

Apply to this trial

tACS to Enhance Language Abilities

for Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06092814·Recruiting·Listed Oct 2023

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Philadelphia, Hershey +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

BLOCK-SAH - PPF-Block for Post-SAH Headache

for Subarachnoid Hemorrhage, Aneurysmal

Sites in Philadelphia +12 more locations

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT06008795·Phase 2·Recruiting·Listed Aug 2023

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CTSN Embolic Protection Trial

for Delirium

Sites in Philadelphia +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

Apply to this trial

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Philadelphia, Hershey +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

for Movement Disorders

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT06848530·Recruiting·Listed Feb 2025

Apply to this trial

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Philadelphia, Pittsburgh +28 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

Apply to this trial

Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children

for Seizures

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 1 Month - 18

Code: NCT03419260·Recruiting·Listed Feb 2018

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Using Smartphones to Improve Physical Activity Levels of Individuals With Spinal Cord Injury

for Spinal Cord Injuries

1 location in Philadelphia

Sponsor: Temple University

Sex: All·Age: 18 - 75

Code: NCT05317832·Phase 2·Recruiting·Listed Apr 2022

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Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

for Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85

Code: NCT06968663·Phase 2·Recruiting·Listed May 2025

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Tele-Exercise to Promote Empowered Movement in Individuals With Spinal Cord Injury

for Spinal Cord Injury

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 18 - 75

Code: NCT07022808·Recruiting·Listed Jun 2025

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Sense4Safety Intervention

for Mild Cognitive Impairment

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 65+

Code: NCT07220668·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Facilitating Access to Specialty Treatment

for Mild Traumatic Brain Injury

1 location in Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 13 - 18

Code: NCT05741411·Recruiting·Listed Feb 2023

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Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

for Delirium

Sites in Philadelphia, Pittsburgh +5 more locations

Sponsor: University of Michigan

Sex: All·Age: 70+

Code: NCT05929703·Recruiting·Listed Jul 2023

Apply to this trial

Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Philadelphia, York +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Longitudinal Assessment of Traumatic Microvascular Injury-2

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05725993·Recruiting·Listed Feb 2023

Apply to this trial

Promoting Recovery After STroke With Amantadine

for Stroke, Ischemic

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 85

Code: NCT05140148·Phase 2·Recruiting·Listed Dec 2021

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

Sites in Philadelphia +34 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019

Apply to this trial

Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

for Stroke

Sites in Philadelphia +1 more location

Sponsor: Temple University

Sex: All·Age: 18+

Code: NCT06530693·Recruiting·Listed Jul 2024

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Localizing Epileptic Networks Using MRI and iEEG

for Epilepsy

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04649008·EARLY_Phase 1·Recruiting·Listed Dec 2020

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Philadelphia, Pittsburgh +39 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

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Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke

for Ischemic Stroke

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 90

Code: NCT04897334·Recruiting·Listed May 2021

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Sildenafil for Microvasculopathy in Chronic TBI

for Traumatic Brain Injury

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 70

Code: NCT05782244·Phase 2·Recruiting·Listed Mar 2023

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Surviving Daily Life

for Stress

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 40+

Code: NCT07054723·Recruiting·Listed Jul 2025

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PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620

for Frontotemporal Lobar Degeneration

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05456503·Phase 3·Recruiting·Listed Jul 2022

Apply to this trial

Parkinson's Disease and Movement Disorders Clinical Database

for Parkinson Disease

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT04997642·Recruiting·Listed Aug 2021

Apply to this trial

Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)

for Alzheimer's Disease

Sites in Philadelphia +1 more location

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 120

Code: NCT05658913·Recruiting·Listed Dec 2022

Apply to this trial

Timing Impact of Early vs. Late Cranioplasty on Hemicraniectomy Outcomes

for Craniocerebral Trauma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06632587·Recruiting·Listed Oct 2024

Apply to this trial

Epilepsy Learning Healthcare System (ELHS)

for Epilepsy

Sites in Philadelphia, Hershey +11 more locations

Sponsor: Epilepsy Foundation of America

Sex: All·Age: All ages

Code: NCT06265103·Recruiting·Listed Feb 2024

Apply to this trial

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

for Aphasia

1 location in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 40 - 85

Code: NCT06842745·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

Sites in Philadelphia +27 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting·Listed Jun 2021

Apply to this trial

Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

Sites in Philadelphia +52 more locations

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting·Listed Aug 2021

Apply to this trial

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

for Myasthenia Gravis

Sites in Philadelphia +9 more locations

Sponsor: Ad scientiam

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05564936·Recruiting·Listed Oct 2022

Apply to this trial

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

for Parkinson's Disease

Sites in Philadelphia +1 more location

Sponsor: University of Nebraska

Sex: All·Age: 18 - 80

Code: NCT05070013·Recruiting·Listed Oct 2021

Apply to this trial

Spinal Cord Injury Registry - North American Clinical Trials Network

for Spinal Cord Injury

Sites in Philadelphia +9 more locations

Sponsor: Robert G. Grossman, MD

Sex: All·Age: 18+

Code: NCT00178724·Recruiting·Listed Sep 2005

Apply to this trial

Environmental and Sensory Intervention for Nursing Home Residents With Dementia Who Exhibit Persistent Vocalizations

for Dementia

1 location in Philadelphia

Sponsor: Drexel University

Sex: All·Age: 50+

Code: NCT06568107·Recruiting·Listed Aug 2024

Apply to this trial

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

for Amyotrophic Lateral Sclerosis

Sites in Philadelphia +4 more locations

Sponsor: Insmed Gene Therapy LLC

Sex: All·Age: 18 - 79

Code: NCT07290062·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

Conditions in Neurology (Philadelphia, PA)

Stroke· 22 Parkinson's disease· 11 Epilepsy· 8 Traumatic brain injury (TBI)· 8 Alzheimer's disease· 7 ALS (amyotrophic lateral sclerosis)· 7 Myasthenia gravis· 6 Spinal cord injury· 6 Mild cognitive impairment (MCI)· 5 Dementia· 5 Multiple sclerosis· 5 Migraine· 5 Aphasia· 3 Cognitive impairment / decline· 3 Headache· 2 Huntington disease· 2 Movement disorders· 2 Essential tremor· 1