As of September 2026, 1,982 paid clinical trials are recruiting in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Philadelphia offers studies at sites including University of Pennsylvania for conditions such as Breast Cancer, Heart Failure, Ovarian Cancer, Prostate Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Philadelphia, PA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Pennsylvania | Heart Failure, Opioid Use Disorder, Colorectal Cancer | 359 |
| Children's Hospital of Philadelphia | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, Pediatric Cancer | 303 |
| Thomas Jefferson University Hospital | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage I Breast Cancer AJCC v8 | 107 |
| Thomas Jefferson University | Focal Epilepsy, Advanced Melanoma, Cancer | 95 |
| Fox Chase Cancer Center | Breast Cancer, Cancer, Urothelial Carcinoma | 94 |
| Hospital of the University of Pennsylvania | Abdominal Aortic Aneurysm, Breast Cancer, Aortic Dissection | 88 |
| Temple University | Amyotrophic Lateral Sclerosis, COPD, Emphysema | 42 |
| The Children's Hospital of Philadelphia | Mitochondrial Diseases, Primary Mitochondrial Disease, 4H Syndrome | 40 |
| Temple University Hospital | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, COPD | 35 |
| University of Pennsylvania/Abramson Cancer Center | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 29 |
| Pennsylvania Hospital | Stroke, Acute, Activity Restriction, Advanced Cancer | 28 |
| Penn Presbyterian Medical Center | Heart Failure, ADHF, Acute Respiratory Failure | 25 |
| Abramson Cancer Center of the University of Pennsylvania | Breast Cancer, Advanced Solid Tumor, Diffuse Large B Cell Lymphoma | 23 |
| Saint Christopher's Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 22 |
| Jefferson Torresdale Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 21 |
| Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA | Parkinson Disease, Stress Disorders, Post-Traumatic, Advanced Urothelial Carcinoma | 19 |
| Sidney Kimmel Cancer Center at Thomas Jefferson University | Breast Cancer, Colorectal Cancer, Cancer | 15 |
| Penn Medicine | Hypertension, ALS, Allogeneic Transplantation | 14 |
| Drexel University | Autism Spectrum Disorder, Obesity, Anxiety | 13 |
| University of Pennsylvania Hospital | Chronic Lymphocytic Leukemia, Neoplasm Metastasis, Non-Hodgkin Lymphoma | 13 |
| University of Pennsylvania, Abramson Cancer Center | Advanced Solid Tumor, Biliary Tract Cancer, Breast Cancer | 13 |
| Childrens Hospital of Philadelphia | Suicide, Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR) | 12 |
| GSK Investigational Site | Asthma, Connective Tissue Diseases, Gastrointestinal Neoplasms | 11 |
| Abramson Cancer Center at University of Pennsylvania | Cardiotoxicity, Renal Cell Carcinoma, AML, Adult | 10 |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Advanced Solid Tumor, Colorectal Cancer, Bladder Cancer | 10 |
Recruiting trials in Philadelphia grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 1,982 recruiting clinical trials in Philadelphia, Pennsylvania listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Philadelphia compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Philadelphia include Breast Cancer (36), Cancer (24), Heart Failure (22), Ovarian Cancer (22), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Philadelphia on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Philadelphia include University of Pennsylvania, Children's Hospital of Philadelphia, Thomas Jefferson University Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Philadelphia are Cancer & tumors (557), Cardiovascular (112), Neurology & pain (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.