Clinical Trials at Thomas Jefferson University

As of August 2026, 88 paid clinical trials are recruiting at Thomas Jefferson University, located at 111 S 11TH ST, SUITE 8270, PHILADELPHIA, PA 19107-4824, phone (215) 955-4038 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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89 clinical trials at Thomas Jefferson University

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Philadelphia, Pittsburgh +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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Virtue® SAB in the Treatment of Coronary ISR Trial

for Coronary Artery Disease

Sites in Philadelphia, York +13 more locations

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT07045194·Recruiting·Listed Jul 2025

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COPD Exacerbation Follow Up

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Philadelphia +3 more locations

Sponsor: Viz.ai, Inc.

Sex: All·Age: 40+

Code: NCT07118306·Recruiting·Listed Aug 2025

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SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Philadelphia +4 more locations

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting·Listed Jan 2024

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A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer

for Carcinoma, Non-small-Cell Lung

Sites in Philadelphia +6 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06116786·Phase 1·Recruiting·Listed Nov 2023

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Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

for Prostate Cancer

Sites in Philadelphia +6 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT06613100·Phase 1·Recruiting·Listed Sep 2024

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Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Sites in Philadelphia +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06704269·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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SPI-1005 in Adults Receiving Cochlear Implant

for Hearing Loss

Sites in Philadelphia +5 more locations

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18+

Code: NCT06340633·Phase 2·Recruiting·Listed Apr 2024

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Contour Neurovascular System™ ContiNued Access Investigational Device EXempTion (IDE) Trial (NEXT Trial)

for Cerebral Aneurysms

Sites in Philadelphia +8 more locations

Sponsor: Cerus Endovascular, Inc.

Sex: All·Age: 18 - 75

Code: NCT06693011·Recruiting·Listed Nov 2024

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VIZ ACCESS HCM - Multi-Site Registry

for Hypertrophic Cardiomyopathy

Sites in Philadelphia +2 more locations

Sponsor: Viz.ai, Inc.

Sex: All·Age: 18+

Code: NCT07103057·Recruiting·Listed Aug 2025

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Radiotherapy for Refractory Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

Sites in Philadelphia +1 more location

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07414550·Recruiting·Listed Feb 2026

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PopSci CHW4CervixHealth

for Cervical Cancer

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 25 - 65·Accepts healthy volunteers

Code: NCT07336134·Recruiting·Listed Jan 2026

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Sites in Philadelphia +38 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting·Listed Aug 2013

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Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER

for Endometrial Cancer

Sites in Philadelphia, Wynnewood +73 more locations

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 18+

Code: NCT05640999·Phase 2·Recruiting·Listed Dec 2022

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

Sites in Philadelphia +32 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting·Listed Oct 2023

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Philadelphia, Pittsburgh +89 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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BLOCK-SAH - PPF-Block for Post-SAH Headache

for Subarachnoid Hemorrhage, Aneurysmal

Sites in Philadelphia +12 more locations

Sponsor: University of Florida

Sex: All·Age: 18 - 85

Code: NCT06008795·Phase 2·Recruiting·Listed Aug 2023

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Philadelphia, Wynnewood +38 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Tebentafusp-tebn With LDT in Metastatic UM

for Metastatic Uveal Melanoma

Drug: Tebentafusp

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06626516·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Philadelphia, West Reading +33 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

Sites in Philadelphia +10 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting·Listed Jul 2021

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Longitudinal Study of the Porphyrias

for Acute Porphyrias

Sites in Philadelphia +14 more locations

Sponsor: The American Porphyrias Expert Collaborative

Sex: All·Age: 1 Minute+

Code: NCT01561157·Recruiting·Listed Mar 2012

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Philadelphia, Paoli +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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ALS/MND Natural History Study Data Repository

for ALS

Sites in Philadelphia, Pittsburgh +12 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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LATe Cerclage in High-risk Pregnancies (LATCH)

for Premature Birth

Sites in Philadelphia +1 more location

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06036446·Recruiting·Listed Sep 2023

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Philadelphia, York +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

for COPD

1 location in Philadelphia

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

Sex: All·Age: 50 - 80

Code: NCT06974981·Recruiting·Listed May 2025

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Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

for Chronic Subdural Hematoma

Sites in Philadelphia +7 more locations

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT06181994·Recruiting·Listed Dec 2023

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Maternal Newborn Health Registry

for Pregnancy Outcome Trends in Low-resource Geographic Areas

Sites in Philadelphia +7 more locations

Sponsor: NICHD Global Network for Women's and Children's Health

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01073475·Recruiting·Listed Feb 2010

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Systemic Hypothermia in Acute Cervical Spinal Cord Injury

for Spinal Cord Injury, Acute

Sites in Philadelphia +4 more locations

Sponsor: University of Miami

Sex: All·Age: 18 - 70

Code: NCT02991690·Recruiting·Listed Dec 2016

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Surviving Daily Life

for Stress

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 40+

Code: NCT07054723·Recruiting·Listed Jul 2025

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IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

for Cancer

Sites in Philadelphia +1 more location

Sponsor: State University of New York at Buffalo

Sex: All·Age: 21+

Code: NCT06206941·Recruiting·Listed Jan 2024

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Cannabis Use and Outcomes in Black and White Patients With Cancer

for Cancer

Sites in Philadelphia +2 more locations

Sponsor: State University of New York at Buffalo

Sex: All·Age: 21 - 99

Code: NCT06037681·Recruiting·Listed Sep 2023

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

Sites in Philadelphia +13 more locations

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting·Listed Sep 2020

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Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)

for Preterm Birth

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16 - 55

Code: NCT06826859·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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Targeted EHR-based Communication of Diagnostic Uncertainty in the ED

for Diagnostic Uncertainty

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06638021·Recruiting·Listed Oct 2024

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Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE

for Uterine Fibroid

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT06705075·Phase 2·Recruiting·Listed Nov 2024

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Reducing Urban Cervical Cancer Disparities

for Cervical Cancer

Sites in Philadelphia +2 more locations

Sponsor: Fox Chase Cancer Center

Sex: Female·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06416150·Recruiting·Listed May 2024

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CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes

for Type 2 Diabetes Mellitus (T2DM)

Sites in Philadelphia +1 more location

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT07184775·Recruiting·Listed Sep 2025

Apply to this trial

Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

Sites in Philadelphia +52 more locations

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting·Listed Aug 2021

Apply to this trial