Clinical Trials at Thomas Jefferson University Hospital

As of August 2026, 112 paid clinical trials are recruiting at Thomas Jefferson University Hospital, located at 132 S 10TH STE 524 MAIN, PHILADELPHIA, PA 19107-5244, phone (215) 955-6000 in Philadelphia, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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112 clinical trials at Thomas Jefferson University Hospital

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Philadelphia, Doylestown +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

Sites in Philadelphia +11 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting·Listed Nov 2020

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Philadelphia, Hershey +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

for Recurrent Endometrial Carcinoma

Sites in Philadelphia +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05950464·Phase 1·Recruiting·Listed Jul 2023

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A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

for Prostate Cancer

Sites in Philadelphia +11 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: Male·Age: 18+

Code: NCT06457919·Phase 1, Phase 2·Recruiting·Listed Jun 2024

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Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for Bladder Cancer

2 locations in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 85

Code: NCT07234968·Recruiting·Listed Nov 2025

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Philadelphia, Pittsburgh +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Philadelphia, Willow Grove +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Philadelphia, Wilkes-Barre +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

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The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

for Osteoporotic Fractures

Sites in Philadelphia +1 more location

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 50+

Code: NCT07027306·Recruiting·Listed Jun 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Philadelphia, Wynnewood +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

Sites in Philadelphia, Pittsburgh +24 more locations

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting·Listed Jul 2022

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Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

for Sickle Cell Disease

Sites in Philadelphia +5 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 15 - 40

Code: NCT06260891·Phase 2·Recruiting·Listed Feb 2024

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Tazemetostat and Palbociclib With CPX-351for R/R AML

for Recurrent Acute Myeloid Leukemia

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05627232·Phase 1·Recruiting·Listed Nov 2022

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Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

Sites in Philadelphia +21 more locations

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting·Listed Dec 2025

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Mozobil for Autologous Hematopoietic Stem Cell Transplantation

for Multiple Myeloma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07188090·Phase 2·Recruiting·Listed Sep 2025

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Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).

for Head and Neck Squamous Cell Carcinoma

Sites in Philadelphia +4 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT05977907·Phase 2·Recruiting·Listed Aug 2023

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Platform Clinical Study for Conquering Scleroderma

for Interstitial Lung Disease Due to Systemic Disease

Sites in Philadelphia +25 more locations

Sponsor: Scleroderma Research Foundation, Inc.

Sex: All·Age: 18+

Code: NCT06195072·Phase 2·Recruiting·Listed Jan 2024

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Left vs Left Randomized Clinical Trial

for Heart Failure

Sites in Philadelphia, Allentown +55 more locations

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting·Listed Dec 2022

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PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial

for Lung Carcinoma

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05775939·Recruiting·Listed Mar 2023

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Home Blood Transfusions

for Hematologic Malignancy

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT07121140·Recruiting·Listed Aug 2025

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Pre-operative SABR With and Without Caloric Restriction for Early Stage Breast Cancer

for Anatomic Stage 0 Breast Cancer AJCC v8

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 40+

Code: NCT04959474·Recruiting·Listed Jul 2021

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The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

for Lung Non-Small Cell Carcinoma

Sites in Philadelphia, Willow Grove & Abington

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT05502523·Recruiting·Listed Aug 2022

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Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies

for Cesarean Delivery

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 16+

Code: NCT07102641·Phase 4·Recruiting·Listed Aug 2025

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Early Antenatal Support for Iron Deficiency Anemia

for Pregnancy Related

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18 - 65

Code: NCT04278651·Phase 4·Recruiting·Listed Feb 2020

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

Sites in Philadelphia +9 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting·Listed Jun 2025

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Perioperative Anticoagulant Use for Surgery Evaluation -2 (PAUSE-2) Study Patients Receiving a Direct Oral Anticoagulant (DOACs-Dabigatran, Rivaroxaban, Apixaban or Edoxaban) and Needing Elective High-Bleed-Risk Surgery or an Invasive Procedure

for Atrial Fibrillation (AF)

Sites in Philadelphia +5 more locations

Sponsor: McMaster University

Sex: All·Age: 18+

Code: NCT06957366·Recruiting·Listed May 2025

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CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Philadelphia +4 more locations

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting·Listed May 2025

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Excretion of Rivaroxaban in Human Breast Milk

for Postpartum

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: Female·Age: 18+

Code: NCT06831474·Phase 1·Recruiting·Listed Feb 2025

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Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)

for Atrial Fibrillation (AF)

Sites in Philadelphia +3 more locations

Sponsor: McMaster University

Sex: All·Age: 18 - 100

Code: NCT06844227·Recruiting·Listed Feb 2025

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Can Medical Cannabis Affect Opioid Use?

for Chronic Pain

1 location in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18+

Code: NCT06206252·Recruiting·Listed Jan 2024

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Philadelphia, Wynnewood +323 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial