Clinical Trials at University of Pittsburgh Medical Center

As of August 2026, 119 paid clinical trials are recruiting at University of Pittsburgh Medical Center, located at 200 LOTHROP ST, 933 W MONTEFIORE, PITTSBURGH, PA 15213-2536, phone (412) 692-4834 in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 24, 2026.

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119 clinical trials at University of Pittsburgh Medical Center

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Active Surveillance in Older Women With ER+ Breast Cancer

for Early Stage Estrogen Receptor (ER) Positive Breast Cancer

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 70+

Code: NCT07262138·Recruiting·Listed Dec 2025

Apply to this trial

Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

Sites in Pittsburgh, Philadelphia +11 more locations

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting·Listed Jan 2024

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The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

for Atopic Dermatitis (AD)

2 locations in Pittsburgh

Sponsor: Daniel Kaplan

Sex: All·Age: 18+

Code: NCT06928246·Phase 1·Recruiting·Listed Apr 2025

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Neuromodulation of Brain and Emotional Responses to Psychological Stress

for Healthy

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 30 - 50·Accepts healthy volunteers

Code: NCT06603064·Recruiting·Listed Sep 2024

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Pittsburgh +24 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

Apply to this trial

Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)

for Cutaneous Squamous Cell Carcinoma

1 location in Pittsburgh

Sponsor: Falo, Louis, MD

Sex: All·Age: 18+

Code: NCT05377905·Phase 1, Phase 2·Recruiting·Listed May 2022

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Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

for Necrotizing Fascitis

Sites in Pittsburgh, Philadelphia +6 more locations

Sponsor: Eric R. Henderson

Sex: All·Age: 18+

Code: NCT06877793·Recruiting·Listed Mar 2025

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Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

for Cervical Deformity

Sites in Pittsburgh +12 more locations

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04194996·Recruiting·Listed Dec 2019

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Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients

for HCV

Sites in Pittsburgh +7 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05653232·Recruiting·Listed Dec 2022

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Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation

for Amputation

1 location in Pittsburgh

Sponsor: Boninger, Michael, MD

Sex: All·Age: 22 - 70

Code: NCT05768802·Recruiting·Listed Mar 2023

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POCUS-Guided Diuresis for Decompensated Heart Failure

for Heart Decompensation, Acute

5 locations in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT06921603·Recruiting·Listed Apr 2025

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Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

for Adult Spinal Deformity

Sites in Pittsburgh +10 more locations

Sponsor: International Spine Study Group Foundation

Sex: All·Age: 18+

Code: NCT04885244·Recruiting·Listed May 2021

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Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for T-Cell Neoplasm

Drug: Pacritinib

Sites in Pittsburgh +5 more locations

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT04858256·Phase 2·Recruiting·Listed Apr 2021

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Adult Patient Outcomes After Spine Surgery With Fibergraft BG Putty/Viper Prime

for Spondylolisthesis, Lumbar Region

1 location in Pittsburgh

Sponsor: Nitin Agarwal

Sex: All·Age: 18+

Code: NCT06704906·Recruiting·Listed Nov 2024

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Conduit Cages and Fibergraft BG Putty

for Degenerative Disc Disease

1 location in Pittsburgh

Sponsor: Nitin Agarwal

Sex: All·Age: 18+

Code: NCT06704919·Recruiting·Listed Nov 2024

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The Myelin Disorders Biorepository Project

for Leukodystrophy

Sites in Pittsburgh, Philadelphia +21 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting·Listed Feb 2017

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Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

for Cystic Fibrosis

Sites in Pittsburgh +17 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 6+

Code: NCT06683092·Recruiting·Listed Nov 2024

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A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Pittsburgh, Hershey +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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Effect of Raised End-Tidal pCo2 on Choroidal Volume

for Intraocular Pressure

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: Up to 8·Accepts healthy volunteers

Code: NCT06275308·Recruiting·Listed Feb 2024

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Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

for Ulcerative Colitis

Sites in Pittsburgh +11 more locations

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT05987852·Recruiting·Listed Aug 2023

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Surveillance vs. Endoscopic Therapy for Barrett's Esophagus With Low-grade Dysplasia

for Barretts Esophagus With Dysplasia

Sites in Pittsburgh, Philadelphia +21 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05753748·Recruiting·Listed Mar 2023

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Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

for Cutaneous T-cell Lymphoma

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT00177268·Recruiting·Listed Sep 2005

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Extracorporeal Photopheresis in Sezary Syndrome

for Sezary Syndrome

Sites in Pittsburgh +2 more locations

Sponsor: Oleg E. Akilov, MD, PhD

Sex: All·Age: 18 - 100

Code: NCT05157581·Recruiting·Listed Dec 2021

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Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents

for Psychological Distress

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 12 - 17

Code: NCT06002191·Recruiting·Listed Aug 2023

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Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD)

for Bipolar Disorder

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT06081426·Recruiting·Listed Oct 2023

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Mobile Health Program for Rural Hypertension

for Hypertension,Essential

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05546931·Recruiting·Listed Sep 2022

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

Sites in Pittsburgh +9 more locations

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting·Listed Mar 2020

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Molecular and Cellular Characterization of Skull Base Tumors

for Skull Base Neoplasm

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: All ages

Code: NCT03759717·Recruiting·Listed Nov 2018

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MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

for Myocardial Infarction

Sites in Pittsburgh +4 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT05933083·Recruiting·Listed Jul 2023

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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

for Neuropathy Ulnar

Sites in Pittsburgh +8 more locations

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT04254185·Recruiting·Listed Feb 2020

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International Rare Histiocytic Disorders Registry (IRHDR)

for Rare Histiocytic Disorders (RHDs)

Sites in Pittsburgh +5 more locations

Sponsor: The Hospital for Sick Children

Sex: All·Age: All ages

Code: NCT02285582·Recruiting·Listed Nov 2014

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Pittsburgh, Philadelphia +50 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

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Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

for Chronic Pancreatitis

Sites in Pittsburgh +2 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04996628·Recruiting·Listed Aug 2021

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QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

for Chronic Pancreatitis

Sites in Pittsburgh +1 more location

Sponsor: Anna Evans Phillips

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03434392·Recruiting·Listed Feb 2018

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A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Pittsburgh, Philadelphia +27 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07623161·Phase 3·Recruiting·Listed Jun 2026

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Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

for Mild Autonomous Cortisol Secretion (MACS)

Drug: Tirzepatide

1 location in Pittsburgh

Sponsor: Alaa Sada

Sex: All·Age: 18+

Code: NCT07573163·Phase 2·Recruiting·Listed May 2026

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in Pittsburgh +19 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Ceribell Delirium Monitor Outcomes Pilot Study

for Delirium in the Intensive Care Unit

Sites in Pittsburgh +1 more location

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT07449416·Recruiting·Listed Mar 2026

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PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

for Coronary Artery Disease Risk Factors Multiple

Sites in Pittsburgh, Philadelphia +21 more locations

Sponsor: Duke University

Sex: All·Age: 30 - 60

Code: NCT07232069·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial