Paid Clinical Trials in Pittsburgh, PA

As of August 2026, 1,248 paid clinical trials are recruiting in Pittsburgh, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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1,100 clinical trials

Cardiac Sarcoidosis Randomized Trial

for Cardiac Sarcoidosis

Sites in Pittsburgh +8 more locations

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT03593759·Phase 3·Recruiting·Listed Jul 2018

Apply to this trial

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

for Recurrent Chronic Lymphocytic Leukemia

Drug: Mirdametinib

Sites in Pittsburgh +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061951·Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

for Oropharynx Cancer

1 location in Pittsburgh

Sponsor: Heath Skinner

Sex: All·Age: 18+

Code: NCT05388773·Phase 2·Recruiting·Listed May 2022

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A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

for Malignant Peritoneal Mesothelioma

Sites in Pittsburgh +12 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06057935·Phase 2·Recruiting·Listed Sep 2023

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in Pittsburgh +19 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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Childhood Cancer Survivor Study

for Cancer

Sites in Pittsburgh, Philadelphia +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

Sites in Pittsburgh +11 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting·Listed Dec 2023

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Study of Carboplatin and Mirvetuximab Soravtansine in First-Line Treatment of Patients Receiving Neoadjuvant Chemotherapy With Advanced-Stage Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for Ovarian Cancer

Sites in Pittsburgh +8 more locations

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT04606914·Phase 2·Recruiting·Listed Oct 2020

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in Pittsburgh +40 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

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Social Threat, Adolescent Relationships, and Suicidality Study

for Suicidal Thoughts and Behaviors

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: Female·Age: 12 - 17

Code: NCT07294079·Recruiting·Listed Dec 2025

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Pittsburgh, Philadelphia +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

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A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)

for Colo-rectal Cancer

Drug: Cemiplimab

Sites in Pittsburgh +8 more locations

Sponsor: NSABP Foundation Inc

Sex: All·Age: 18+

Code: NCT07058012·Phase 2·Recruiting·Listed Jul 2025

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Pittsburgh +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

Collection of Tissue Samples for Cancer Research

for Neoplasms

Sites in Pittsburgh +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting·Listed May 2009

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Pittsburgh +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting·Listed Jun 2025

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Pittsburgh, Hershey +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

for Diabetes Mellitus, Type 2

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 16 - 24

Code: NCT07270016·Recruiting·Listed Dec 2025

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Pittsburgh, Hershey +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

Apply to this trial

Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis

for Stroke

1 location in Pittsburgh

Sponsor: Marco Capogrosso

Sex: All·Age: 22 - 70

Code: NCT07153536·Recruiting·Listed Sep 2025

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Testing the Combination of Anti-cancer Drugs, Tovorafenib Plus Rituximab, in Patients With Hairy Cell Leukemia

for Hairy Cell Leukemia

Drug: Rituximab

Sites in Pittsburgh +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06965114·Phase 1, Phase 2·Recruiting·Listed May 2025

Apply to this trial

Pollution Intervention to Impact Kids Asthma Study

for Childhood Asthma

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 8 - 17

Code: NCT07261423·Recruiting·Listed Dec 2025

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Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

for Concussion, Mild

Sites in Pittsburgh +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 49

Code: NCT06819904·Recruiting·Listed Feb 2025

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Circulating Tumor DNA

for ER+ Breast Cancer

Sites in Pittsburgh +6 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06923527·Phase 2·Recruiting·Listed Apr 2025

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I-DECIDE After Bronchiolitis Hospitalization

for Bronchiolitis Acute

Sites in Pittsburgh, Philadelphia +54 more locations

Sponsor: Seattle Children's Hospital

Sex: All·Age: 0 Months - 24 Months

Code: NCT07243652·Recruiting·Listed Nov 2025

Apply to this trial

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Pittsburgh, Wynnewood +38 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Comparing Surgical and Endovascular Arteriovenous Fistula Creation

for End Stage Renal Disease on Dialysis

Sites in Pittsburgh +1 more location

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 99

Code: NCT05654103·Recruiting·Listed Dec 2022

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Pittsburgh, Philadelphia +69 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

Apply to this trial

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

for Adults With Variability in Their Mood

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07252011·Recruiting·Listed Nov 2025

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Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

for Diabetes in Adolescence

1 location in Pittsburgh

Sponsor: University of Pittsburgh

Sex: All·Age: 13+·Accepts healthy volunteers

Code: NCT07216118·Recruiting·Listed Oct 2025

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Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

for Inherited Retinal Degeneration

Sites in Pittsburgh, Philadelphia +17 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4+

Code: NCT05589714·Recruiting·Listed Oct 2022

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Pittsburgh, Hershey +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

for Gestational Diabetes

Sites in Pittsburgh +4 more locations

Sponsor: Indiana University

Sex: Female·Age: 18 - 45

Code: NCT05124808·Recruiting·Listed Nov 2021

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Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

for Opioid Use Disorder

1 location in Pittsburgh

Sponsor: Ilana Hull

Sex: Female·Age: 18+

Code: NCT05942313·Recruiting·Listed Jul 2023

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Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe Asthma

for Asthma

Drug: Dupilumab

1 location in Pittsburgh

Sponsor: Sally E. Wenzel MD

Sex: All·Age: 18+

Code: NCT04743791·Phase 4·Recruiting·Listed Feb 2021

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Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

for Familial Mediterranean Fever (FMF)

Sites in Pittsburgh +1 more location

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 2 Months - 115·Accepts healthy volunteers

Code: NCT00001373·Recruiting·Listed Nov 1999

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Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

for Melanoma

1 location in Pittsburgh

Sponsor: Dan Zandberg

Sex: All·Age: 18+

Code: NCT04114136·Phase 2·Recruiting·Listed Oct 2019

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Testing the Safety and Efficacy of the Addition of a New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Cisplatin and Etoposide or Carboplatin and Paclitaxel) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

for Advanced NUT Carcinoma

Sites in Pittsburgh +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT05019716·Phase 1, Phase 2·Recruiting·Listed Aug 2021

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Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

for Metastatic Dedifferentiated Liposarcoma

Drug: Peposertib

Sites in Pittsburgh +14 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05711615·Phase 1·Recruiting·Listed Feb 2023

Apply to this trial

Clinical and Laboratory Study of Methylmalonic Acidemia

for Organic Acidemia

Sites in Pittsburgh +1 more location

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 115·Accepts healthy volunteers

Code: NCT00078078·Recruiting·Listed Feb 2004

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Pittsburgh, Hershey +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

Apply to this trial