As of July 2026, 77 paid clinical trials are recruiting in Portland, Maine. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Portland offers studies at sites including MaineHealth Maine Medical Center - Portland for conditions such as Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Portland, ME at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MaineHealth Maine Medical Center - Portland | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 23 |
| Maine Medical Center | Atrial Fibrillation, Heart Failure, ADHD | 20 |
| MaineHealth | Aging, Alzheimer Disease, Aneurysmal Subarachnoid Hemorrhage (aSAH) | 4 |
| Maine Medical Partners Pediatric Specialty Care | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Maine Eye Center | Geographic Atrophy, Macular Degeneration, Neovascular Age-related Macular Degeneration | 3 |
| Maine Health | Cancer, Irritable Bowel Syndrome With Constipation (IBS-C), Myocarditis Acute | 2 |
| MaineHealth Maine Medical Center | Burn (Disorder), Burn Degree Second, Burns Degree Third | 2 |
| Portland Gastroenterology Center | Celiac Disease, Crohn's Disease, Ulcerative Colitis | 2 |
| Maine Eye Center - Marginal Way Campus | AMD, CNV, Wet Age-related Macular Degeneration | 2 |
| Eyecare Medical Group | Dry Age Related Macular Degeneration, Epiretinal Membrane, IS/OS (Ellipsoid Zone) Disruption | 1 |
| GSK Investigational Site | Multiple Myeloma, Newly Diagnosed Multiple Myeloma | 1 |
| Maine Health - Maine Medical Center | Homocystinuria | 1 |
| Maine Health Pediatric Specialty Care | Homocystinuria | 1 |
| Maine Health Research Institute | Type 1 Diabetes | 1 |
| Maine Medical Center - Bramhall Campus | Hepatitis | 1 |
| Maine Medical Center - Division of Pulmonary and Critical Care Medicine | Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI), Pancreatic Diseases | 1 |
| Maine Medical Center-Bramhall Campus | Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 | 1 |
| Maine Medical Centre | Community-acquired Pneumonia | 1 |
| Maine Medical Partners | Colitis, Ulcerative | 1 |
| MaineHealth Maine Medical Center Portland | Interprofessional Education, Neonatal Resuscitation, Rural Health | 1 |
| MaineHealth Pediatric Specialty Care | Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI) | 1 |
| Northern Light Breast Care | Breast Cancer | 1 |
| Ovation.io | Cancer, Other Disease | 1 |
| Portland Gastroenterology Center - Portland - Congress Street | Crohn's Disease, Ulcerative Colitis | 1 |
| The Vascular Care Group | PAD, Peripheral Artery Calcification, Peripheral Artery Disease | 1 |
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 77 recruiting clinical trials in Portland, Maine listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Portland include Acute Myeloid Leukemia (6), Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm (2), Acute Myeloid Leukemia Post Cytotoxic Therapy (2), Acute Myeloid Leukemia, Myelodysplasia-Related (2), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Portland include MaineHealth Maine Medical Center - Portland, Maine Medical Center, MaineHealth, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Portland are Cancer & tumors (25), Cardiovascular (8), Eye & vision (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.