Paid Clinical Trials in Portland, ME
As of July 2026, 77 paid clinical trials are recruiting in Portland, Maine. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Portland offers studies at sites including MaineHealth Maine Medical Center - Portland for conditions such as Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Portland
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1 clinical trial
·Clear filters·Top Research Study Locations in Portland
Researchers run research studies in Portland, ME at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MaineHealth Maine Medical Center - Portland | Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy | 23 |
| Maine Medical Center | Atrial Fibrillation, Heart Failure, ADHD | 20 |
| MaineHealth | Aging, Alzheimer Disease, Aneurysmal Subarachnoid Hemorrhage (aSAH) | 4 |
| Maine Medical Partners Pediatric Specialty Care | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Maine Eye Center | Geographic Atrophy, Macular Degeneration, Neovascular Age-related Macular Degeneration | 3 |
| Maine Health | Cancer, Irritable Bowel Syndrome With Constipation (IBS-C), Myocarditis Acute | 2 |
| MaineHealth Maine Medical Center | Burn (Disorder), Burn Degree Second, Burns Degree Third | 2 |
| Portland Gastroenterology Center | Celiac Disease, Crohn's Disease, Ulcerative Colitis | 2 |
| Maine Eye Center - Marginal Way Campus | AMD, CNV, Wet Age-related Macular Degeneration | 2 |
| Eyecare Medical Group | Dry Age Related Macular Degeneration, Epiretinal Membrane, IS/OS (Ellipsoid Zone) Disruption | 1 |
| GSK Investigational Site | Multiple Myeloma, Newly Diagnosed Multiple Myeloma | 1 |
| Maine Health - Maine Medical Center | Homocystinuria | 1 |
| Maine Health Pediatric Specialty Care | Homocystinuria | 1 |
| Maine Health Research Institute | Type 1 Diabetes | 1 |
| Maine Medical Center - Bramhall Campus | Hepatitis | 1 |
| Maine Medical Center - Division of Pulmonary and Critical Care Medicine | Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI), Pancreatic Diseases | 1 |
| Maine Medical Center-Bramhall Campus | Castration Levels of Testosterone, Metastatic Prostatic Adenocarcinoma, Stage IV Prostate Cancer AJCC v8 | 1 |
| Maine Medical Centre | Community-acquired Pneumonia | 1 |
| Maine Medical Partners | Colitis, Ulcerative | 1 |
| MaineHealth Maine Medical Center Portland | Interprofessional Education, Neonatal Resuscitation, Rural Health | 1 |
| MaineHealth Pediatric Specialty Care | Cystic Fibrosis (CF), Exocrine Pancreatic Insufficiency (EPI) | 1 |
| Northern Light Breast Care | Breast Cancer | 1 |
| Ovation.io | Cancer, Other Disease | 1 |
| Portland Gastroenterology Center - Portland - Congress Street | Crohn's Disease, Ulcerative Colitis | 1 |
| The Vascular Care Group | PAD, Peripheral Artery Calcification, Peripheral Artery Disease | 1 |
Active & Upcoming Studies in Portland (2026)
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (25 active studies)
- Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer · Phase 3 · National Cancer Institute (NCI)
- Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer · Phase 3 · NRG Oncology
Cardiovascular (8 active studies)
- Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure · Abbott Medical Devices
- CTSN Embolic Protection Trial · Icahn School of Medicine at Mount Sinai
Eye & vision (6 active studies)
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) · Phase 2, Phase 3 · EyeBiotech Ltd.
- Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) · Phase 3 · AbbVie
Neurology & pain (3 active studies)
- Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders · University of Michigan
- CTSN Embolic Protection Trial · Icahn School of Medicine at Mount Sinai
Diabetes & metabolic (2 active studies)
Pediatric (2 active studies)
- Comparative Study of Simulation Technologies for Use in Neonatal Resuscitation Training for Rural Hospitals · MaineHealth
- Supraglottic Airway for Resuscitation Trial · Children's Hospital of Philadelphia
Common conditions studied in Portland
- Acute Myeloid Leukemia (6 active studies)
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm (2 active studies)
- Acute Myeloid Leukemia Post Cytotoxic Therapy (2 active studies)
- Acute Myeloid Leukemia, Myelodysplasia-Related (2 active studies)
- Atrial Fibrillation (2 active studies)
- Cancer (2 active studies)
Leading research sponsors in Portland
- National Cancer Institute (NCI)
- NRG Oncology
- AbbVie
- Alliance for Clinical Trials in Oncology
- Genzyme, a Sanofi Company
Frequently asked questions
How many paid clinical trials are currently recruiting in Portland?
There are approximately 77 recruiting clinical trials in Portland, Maine listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Portland pay participants?
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Portland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Portland?
The most common conditions under active study in Portland include Acute Myeloid Leukemia (6), Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm (2), Acute Myeloid Leukemia Post Cytotoxic Therapy (2), Acute Myeloid Leukemia, Myelodysplasia-Related (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Portland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Portland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Portland?
Recruiting research sites in Portland include MaineHealth Maine Medical Center - Portland, Maine Medical Center, MaineHealth, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Portland right now?
The largest active categories in Portland are Cancer & tumors (25), Cardiovascular (8), Eye & vision (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.