A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
for Advanced Solid Tumor
14 locations incl. Los Angeles
Sponsor: Volastra Therapeutics, Inc.
Sex: All·Age: 18+
Code: NCT05902988·Phase 1, Phase 2·Recruiting
Head and neck cancer Clinical Trials in Providence, RI
As of June 2026, 2 paid clinical trials are recruiting for Head and neck cancer in Providence, Rhode Island. Recruiting Head and neck cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Related specialties in Providence
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2 clinical trials for Head and neck cancer
·Clear filters·↓ Download CSVStudy of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
for Head and Neck Squamous Cell Carcinoma
15 locations incl. La Jolla
Sponsor: Bicara Therapeutics
Sex: All·Age: 18+
Code: NCT04429542·Phase 1·Recruiting
About research studies in Providence
Providence has approximately 449 recruiting research studies across a wide range of therapeutic areas. Rhode Island hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.
Top Research Study Locations in Providence
Researchers run research studies in Providence, RI at 50 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Rhode Island Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm | 122 |
| Brown University | Alcohol Use Disorder, Alcohol Use Disorder (AUD), Perceptual Learning | 35 |
| Women and Infants Hospital | Recurrent Endometrial Carcinoma, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8 | 26 |
| Butler Hospital | Alzheimers Disease, Depression, Alzheimers Disease, Familial | 18 |
| Hasbro Children's Hospital | Neuroblastoma, Intubation Complication, Bronchiolitis Acute | 13 |
| The Miriam Hospital | Acute Stress Disorder, Acute Stress Reaction, Biological Markers of Inflammation | 13 |
| Providence VA Medical Center, Providence, RI | Alcohol Use Disorder, Amyotrophic Lateral Sclerosis, Attention Deficit Disorder With Hyperactivity | 11 |
| University Gastroenterology | Crohn's Disease, Ulcerative Colitis, Obesity or Overweight | 11 |
| Women & Infants Hospital | Advanced Solid Tumor, Breast Cancer, Cancer | 11 |
| Brown University Health | Advanced Solid Tumors Cancer, Aging, Brain Tumor | 8 |
| Miriam Hospital | Adenocarcinoma, Pancreatic Ductal, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 8 |
| Lifespan Cancer Institute | Adolescent, Advanced Solid Tumor, Carcinoma, Non-Small-Cell Lung | 7 |
| Brown University School of Public Health | Alcohol Use Disorder, Behavioral Economics, Cannabis Smoking | 6 |
| Women & Infants Hospital of Rhode Island | Cervical Cancer, Endometrial Cancer, Genetic Counseling | 6 |
| Providence Veterans Administration Hospital | Malignant Solid Neoplasm, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | 5 |
| Roger Williams Medical Center | Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Advanced Malignant Solid Neoplasm | 5 |
| Providence VA Medical Center | Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Cardiovascular Diseases | 4 |
| Women and Infants Hospital of Rhode Island | Breast Adenocarcinoma, Endometrial Cancer, Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC) | 4 |
| Lifespan | Malignant Peripheral Nerve Sheath Tumors, Pulmonary Embolism, Sickle Cell Disease | 3 |
| Rhode Island Hospital Genetics | Cerebroside Lipidosis Syndrome, Fabry Disease, Gaucher Disease | 3 |
| Weight Control and Diabetes Research Center | Adolescent Obesity, Cardiometabolic Risk Factors, Eating Behavior | 3 |
| Brown Univeristy | Obstetrical Complications, Cesarean Delivery, Labor and Delivery Complication | 2 |
| Brown University Health Cancer Institute | ALK Genomic Tumor Aberrations, Advanced Cancer, Advanced Solid Tumor | 2 |
| Brown University, Women & Infants Hospital of Rhode Island | Infant, Low Birth Weight, Infant, Newborn, Infant, Premature | 2 |
| Brown University/Rhode Island Hospital | Post Operative Surgical Site Infection, Pulmonary Arterial Hypertension (PAH) | 2 |
| Brown/ Women and Infants Hospital of Rhode Island, Division of Urogynecology and Reconstructive Pelvic Surgery | Mixed Urinary Incontinence, Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP) | 2 |
| Gastroenterology Associates | Ulcerative Colitis, Crohn Disease, Crohn's Disease | 2 |
| Obstetrics and Gynecology Care Center | Health Disparity, Minority and Vulnerable Populations, Perinatal Outcomes, Postpartum Psychiatric Disorders | 2 |
| University Gastroenterology - GI Alliance | Crohn's Disease, Ulcerative Colitis | 2 |
| Weight Control & Diabetes Research Center | Binge-Eating Disorder, Obesity, Pediatric Obesity | 2 |
| Brown University Health - Rhode Island Hospital | B-Cell Non-Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Relapsed B-Cell Non-Hodgkin Lymphoma | 2 |
| Lifespan Cancer Institute at Rhode Island Hospital | Advanced Solid Tumor Cancer, Metastatic Castration-Resistant Prostate Cancer | 2 |
| University Gastroenterology - Providence - West River Street | Ulcerative Colitis, Crohn's Disease | 2 |
| #1007, Rhode Island Hospital | Advanced Solid Tumor | 1 |
| #1030, Women & Infants Hospital of Rhode Island | Advanced Solid Tumor | 1 |
| 235 Plain Street | Carpometacarpal Sprain, Clostridium; Botulinum, Thumb Sprain | 1 |
| 2951, The Miriam Hospital (TMH) CRS | Acute HIV Infection | 1 |
| Alzheimer's Disease and Memory Disorders Center at Rhode Island Hospital | Alzheimer Disease | 1 |
| Bradley Hasbro Children's Research Center | Depressive Symptoms, Suicidal Behaviors, Suicide Ideation | 1 |
| Brown Health | Dysfunctional AV Fistula, Dysfunctional AV Graft, Peripheral Artery Disease (PAD) | 1 |
| Brown Physicians, Inc | Manual Ventilation | 1 |
| Brown University - Rhode Island Hospital | Community-acquired Pneumonia, Influenza, COVID-19 | 1 |
| Brown University Cancer Institute | Locally Advanced Pancreatic Adenocarcinoma | 1 |
| Brown University Health - Lipid Clinic | Hypertriglyceridemia, Lipid Metabolism Disorders | 1 |
| Brown University Health/Rhode Island Hospital | Astrocytoma, Astrocytoma, IDH-Mutant, GBM | 1 |
| Brown University Magnetic MRI Research Facility | Episodic Memory | 1 |
| Brown University OBGYN | Health Disparity, Minority and Vulnerable Populations, Perinatal Outcomes, Pregnancy | 1 |
| Brown University Women's Medicine and Collaborative | Clostridium Difficile Infection, Fecal Microbiota Transplantation, Gut Microbiome | 1 |
| Brown University/Lifespan | Cardiovascular Health | 1 |
| Brown surgical associates | Anal Fistula | 1 |
Active & Upcoming Studies in Providence (2026)
Recruiting trials in Providence grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (148 active studies)
- Basal Cell Carcinoma Chemoprevention Trial · Phase 3 · VA Office of Research and Development
- First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer · Phase 1, Phase 2 · AstraZeneca
Neurology & pain (28 active studies)
Cardiovascular (28 active studies)
Diabetes & metabolic (22 active studies)
- Pilot of Food Is Medicine Interventions to Reduce Cardiovascular Disease Risk in Children With Food Insecurity and Diabetes · Katelyn Fox
- Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs · California Polytechnic State University-San Luis Obispo
Mental health & behavior (17 active studies)
- Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days · Phase 3 · VA Office of Research and Development
- Intraoperative Music Therapy in TAVR Patients · Rhode Island Hospital
Pediatric (12 active studies)
- Stress Reactivity and Mother-Infant Cardiovascular Disease Risk · Lifespan
- Community-Partnered Doula Support for Neonatal Intensive Care Unit Families · Women and Infants Hospital of Rhode Island
HIV / STI (8 active studies)
- Bringing Medicines for HIV Prevention to a Family Planning Clinic · Women and Infants Hospital of Rhode Island
- Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults · Westat
Vaccines (6 active studies)
- A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease · Phase 2 · Shionogi
- Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy · Phase 4 · Women and Infants Hospital of Rhode Island
Common conditions studied in Providence
- Crohn's Disease (9 active studies). Recruiting Crohn's Disease studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Endometrial Cancer (9 active studies). Recruiting Endometrial Cancer studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Ulcerative Colitis (9 active studies). Ulcerative colitis trials examine biologic therapies, S1P receptor modulators, and oral small molecules for steroid-sparing remission.
- Acute Myeloid Leukemia (8 active studies). Leukemia trials evaluate targeted inhibitors, CAR-T cell therapies, and novel combinations for acute and chronic forms of the disease.
- Advanced Solid Tumor (8 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
- Breast Cancer (8 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
Leading research sponsors in Providence
- Brown University
- AstraZeneca
- National Cancer Institute (NCI)
- Rhode Island Hospital
- Children's Oncology Group
Local regulations and guidelines
Clinical trials in Rhode Island are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Rhode Island research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Providence. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Providence
Hipa.ai aggregates every recruiting study in Providence from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Providence?
There are approximately 449 recruiting clinical trials in Providence, Rhode Island listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Providence pay participants?
Most recruiting trials in Providence compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Providence?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Providence?
The most common conditions under active study in Providence include Crohn's Disease (9), Endometrial Cancer (9), Ulcerative Colitis (9), Acute Myeloid Leukemia (8), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Providence?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Providence on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Providence?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Providence?
Recruiting research sites in Providence include Rhode Island Hospital, Brown University, Women and Infants Hospital, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Providence right now?
The largest active categories in Providence are Cancer & tumors (148), Neurology & pain (28), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.