Clinical Trials at University of Texas Health Science Center at San Antonio

As of August 2026, 81 paid clinical trials are recruiting at University of Texas Health Science Center at San Antonio, located at 8210 FLOYD CURL DR, SAN ANTONIO, TX 78229-3923, phone (210) 567-6405 in San Antonio, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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82 clinical trials at University of Texas Health Science Center at San Antonio

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in San Antonio, Austin +70 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in San Antonio, Austin +100 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in San Antonio, Austin +162 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

Sites in San Antonio, Austin +148 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting·Listed Sep 2020

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Shared Decision Making in PTSD Treatment

for Post Traumatic Stress Disorder PTSD

Sites in San Antonio & Fort Hood

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18+

Code: NCT06953687·Recruiting·Listed May 2025

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Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

Sites in San Antonio, Houston +16 more locations

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting·Listed Dec 2023

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in San Antonio, Houston +89 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in San Antonio, Houston +18 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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Artificial Intelligence Prediction Tool in Non-muscle Invasive Bladder Cancer (NMIBC)

for Non-muscle-invasive Bladder Cancer

Sites in San Antonio & Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05825950·Recruiting·Listed Apr 2023

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Quantifying Hepatic Mitochondrial Fluxes in Humans

for Non-Alcoholic Fatty Liver Disease

2 locations in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 80

Code: NCT05305287·Phase 4·Recruiting·Listed Mar 2022

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Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer

for Breast Cancer

Sites in San Antonio, Houston +2 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07076485·Phase 2·Recruiting·Listed Jul 2025

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Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

for Spinal Cord Injuries

2 locations in San Antonio

Sponsor: Marzieh Salehi

Sex: All·Age: 18 - 70

Code: NCT06706284·Phase 4·Recruiting·Listed Nov 2024

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in San Antonio, Austin +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

for Solid Tumor

1 location in San Antonio

Sponsor: Lei Zheng

Sex: All·Age: 18+

Code: NCT07086768·Phase 1·Recruiting·Listed Jul 2025

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in San Antonio, Houston +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

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Transformative Research in Diabetic Nephropathy

for Diabetic Nephropathies

Sites in San Antonio +12 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 100

Code: NCT02986984·Recruiting·Listed Dec 2016

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in San Antonio, Houston +52 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

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SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

for Type2 Diabetes

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 80

Code: NCT05057806·EARLY_Phase 1·Recruiting·Listed Sep 2021

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

Sites in San Antonio, Sugar Land +292 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018

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Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults

for Obesity Prevention

Drug: Tirzepatide

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 50+

Code: NCT06811324·Phase 2·Recruiting·Listed Feb 2025

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Blood Flow Restriction for Optimizing Balance in Parkinson's Disease

for Parkinson's Disease and Parkinsonism

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 40 - 85

Code: NCT06508801·Recruiting·Listed Jul 2024

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

Sites in San Antonio, Houston +97 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting·Listed Jun 2023

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Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

for Acute Stress Reaction

Sites in San Antonio +8 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 55

Code: NCT06636786·Phase 2·Recruiting·Listed Oct 2024

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

Sites in San Antonio, Houston +26 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting·Listed Jun 2021

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Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

for Huntington Disease

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 85

Code: NCT06843252·Recruiting·Listed Feb 2025

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Advancing Alzheimer's Care: Home-based tDCS for Affective Symptoms

for Alzheimer Disease

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 60 - 85

Code: NCT06801639·Recruiting·Listed Jan 2025

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Chromosome 18 Clinical Research Center

for Chromosome Aberrations

2 locations in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT00227253·Recruiting·Listed Sep 2005

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Ultrasound for Healthy Aging

for Aging

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 70+·Accepts healthy volunteers

Code: NCT07168525·Recruiting·Listed Sep 2025

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The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

for Dental Implantation

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 18·Accepts healthy volunteers

Code: NCT07053969·Recruiting·Listed Jul 2025

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Microsurgery and Periodontal Healing

for Periodontal Diseases

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 18·Accepts healthy volunteers

Code: NCT07054008·Recruiting·Listed Jul 2025

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in San Antonio, Houston +128 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in San Antonio, Houston +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

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Prevention of Progression of Prediabetes, Obesity and CV Risk

for Pre-Diabetes

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18+

Code: NCT06446531·Phase 1·Recruiting·Listed Jun 2024

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Combining Stellate Ganglion Block With Prolonged Exposure for PTSD

for Stress Disorders, Post-Traumatic

Sites in San Antonio & Fort Hood

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05889741·Phase 2·Recruiting·Listed Jun 2023

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Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

for Premature

Sites in San Antonio +6 more locations

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: Up to 36 Weeks

Code: NCT05380401·Recruiting·Listed May 2022

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Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals

for HIV Prevention

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 34·Accepts healthy volunteers

Code: NCT06745947·Recruiting·Listed Dec 2024

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

Sites in San Antonio, Austin +112 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

for Type 2 Diabetes

1 location in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 18 - 80

Code: NCT06108076·EARLY_Phase 1·Recruiting·Listed Oct 2023

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Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

for Posttraumatic Stress Disorder

1 location in San Antonio

Sponsor: Penn State University

Sex: All·Age: 18+

Code: NCT06047691·Recruiting·Listed Sep 2023

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A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for Rhabdomyosarcoma

Sites in San Antonio, Austin +83 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT07466316·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial