Paid Clinical Trials in San Antonio, TX
As of July 2026, 986 paid clinical trials are recruiting in San Antonio, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
San Antonio offers studies at sites including University of Texas Health Science Center at San Antonio for conditions such as Advanced Solid Tumor, Advanced Solid Tumors, Breast Cancer, Obesity. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in San Antonio
Trials by drug in San Antonio
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Newly added in San Antonio
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Oil Pulling Reduction
A Study of SHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid Tumors
mHealth to Improve Medication Adherence Among Latina Breast Cancer Patients Experiencing Non-Medical Drivers of Health
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy
911 clinical trials
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
A Study of Solbinsiran (LY3561774) in Participants With Severe Hypertriglyceridemia
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Top Research Study Locations in San Antonio
Researchers run research studies in San Antonio, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Texas Health Science Center at San Antonio | Cardiovascular Diseases, Type 2 Diabetes, Acute Myeloid Leukemia | 86 |
| NEXT Oncology | Advanced Solid Tumor, Advanced Solid Tumors, NSCLC | 56 |
| Children's Hospital of San Antonio | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 31 |
| Methodist Children's Hospital of South Texas | B Acute Lymphoblastic Leukemia, Malignant Solid Neoplasm, Acute Myeloid Leukemia | 24 |
| START San Antonio | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 23 |
| The University of Texas Health Science Center at San Antonio | Aging, Bladder Carcinoma, Blood Pressure | 22 |
| UT Health San Antonio | Focal Epilepsy, Colorectal Cancer, Pancreatic Cancer | 16 |
| Texas Dermatology and Laser Specialists | Atopic Dermatitis, Eczema, Plaque Psoriasis | 14 |
| GSK Investigational Site | Non-alcoholic Fatty Liver Disease, Neoplasms, Gastrointestinal Neoplasms | 13 |
| Texas Oncology - San Antonio | Colorectal Neoplasms, Pancreatic Ductal Adenocarcinoma, Acinar Cell Carcinoma | 12 |
| Brooke Army Medical Center | Carpal Tunnel Syndrome, Chronic Pain, Combat Casualty Care | 12 |
| American Research Corporation at the Texas Liver Institute | Healthy, Hepatic Impairment, Liver Cirrhosis | 10 |
| Southern Star Research Institute | Colitis, Ulcerative, Crohn Disease, Irritable Bowel Syndrome | 9 |
| University Hospital | Hemorrhage, Surgical, Tonsillar Bleeding, CMV | 9 |
| Endeavor Clinical Trials | Obesity, Overweight, Cardiovascular Diseases | 8 |
| NEXT San Antonio | Advanced Solid Tumors, Endometrial Cancer, Cervical Cancer | 8 |
| South Texas Accelerated Research Therapeutics (START) | Advanced Solid Tumors, Head and Neck Squamous Cell Carcinoma, Non-small Cell Lung Cancer | 8 |
| Southern Star Research Institute, LLC | Colitis, Ulcerative, Crohn Disease, Crohn's Disease | 8 |
| Sun Research Institute | Pneumococcal Disease, Chronic Idiopathic Constipation (CIC), Hypertension (HTN) | 7 |
| Texas Transplant Institute | Large B-cell Lymphoma, Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma | 7 |
| Urology San Antonio | Prostate Cancer, FGFR Gene Alterations, FGFR Gene Amplification | 7 |
| IMA Clinical Research San Antonio | Obesity, Overweight, Cardiovascular Diseases | 6 |
| Methodist Hospital | AMI Cardiogenic Shock, Acute Kidney Injury, Aortic Stenosis | 6 |
| START - San Antonio | Advanced Solid Tumors, Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC), Advanced or Metastatic ER+ HER2- Breast Cancer (mBC) | 6 |
| South Texas Health Care System, San Antonio, TX | Adult Growth Hormone Deficiency, Alcohol Use Disorder (AUD), Chronic Low Back Pain | 6 |
Active & Upcoming Studies in San Antonio (2026)
Recruiting trials in San Antonio grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (303 active studies)
- Genetic Investigation of Cancer Predisposition · The University of Texas Health Science Center at San Antonio
- SCIPI Implementation and Evaluation: A Multi-site Proof-of-Concept Pilot Trial · The University of Texas Health Science Center at San Antonio
Diabetes & metabolic (85 active studies)
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
- Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1) · Phase 3 · Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Neurology & pain (44 active studies)
- SwallowFIT Study in Parkinson's Disease · The University of Texas Health Science Center at San Antonio
- DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea. · Phase 2 · Incannex Healthcare Ltd
Cardiovascular (35 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic: A Stepped Wedge Cluster Randomized Trial · Driscoll Children's Hospital
Eye & vision (20 active studies)
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
Mental health & behavior (16 active studies)
Pediatric (12 active studies)
- MiniMed Fit Payload Wear Pediatric Study · Medtronic MiniMed, Inc.
- PULSE - Patient Understanding and Learning Through Structured Education - Effectiveness and Implementation of Patient Education Videos in a New Pediatric Cardiology Clinic: A Stepped Wedge Cluster Randomized Trial · Driscoll Children's Hospital
HIV / STI (4 active studies)
- Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions · Phase 2 · AusperBio Therapeutics Inc.
- Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals · The University of Texas Health Science Center at San Antonio
Vaccines (3 active studies)
Common conditions studied in San Antonio
- Advanced Solid Tumor (40 active studies)
- Advanced Solid Tumors (30 active studies)
- Breast Cancer (27 active studies)
- Obesity (27 active studies)
- Ovarian Cancer (22 active studies)
- Colorectal Cancer (21 active studies)
Leading research sponsors in San Antonio
- The University of Texas Health Science Center at San Antonio
- Eli Lilly and Company
- AstraZeneca
- Bristol-Myers Squibb
- Children's Oncology Group
Frequently asked questions
How many paid clinical trials are currently recruiting in San Antonio?
There are approximately 986 recruiting clinical trials in San Antonio, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in San Antonio pay participants?
Most recruiting trials in San Antonio compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in San Antonio?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in San Antonio?
The most common conditions under active study in San Antonio include Advanced Solid Tumor (40), Advanced Solid Tumors (30), Breast Cancer (27), Obesity (27), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in San Antonio?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in San Antonio on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in San Antonio?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in San Antonio?
Recruiting research sites in San Antonio include University of Texas Health Science Center at San Antonio, NEXT Oncology, Children's Hospital of San Antonio, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in San Antonio right now?
The largest active categories in San Antonio are Cancer & tumors (303), Diabetes & metabolic (85), Neurology & pain (44). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.