Paid Clinical Trials in San Diego, CA

As of July 2026, 747 paid clinical trials are recruiting in San Diego, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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638 clinical trials

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GORE® ENFORM Biomaterial Product Study

for Hernia, Ventral

Sites in San Diego +8 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT04718168·Recruiting·Listed Jan 2021

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A Multicenter, Prospective Blood Collection Study in a Kidney Transplant Population

for Kidney Disease

Sites in San Diego, San Francisco +4 more locations

Sponsor: Devyser Inc.

Sex: All·Age: 18+

Code: NCT07006831·Recruiting·Listed Jun 2025

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A Study to Evaluate Efficacy and Safety of Light Dose in Subjects With PWB Treated With Hemoporfin PDT

for Port-wine Birthmarks

Sites in San Diego, Irvine +3 more locations

Sponsor: Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 75

Code: NCT05171894·Phase 2·Recruiting·Listed Dec 2021

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Safety Study for Prospective Assessment of Pregnancy Outcomes in Patients Treated With Tildrakizumab

for Pregnancy Related

1 location in San Diego

Sponsor: Sun Pharmaceutical Industries Limited

Sex: Female·Age: All ages

Code: NCT03992729·Recruiting·Listed Jun 2019

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HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome

for Angelman Syndrome

Sites in San Diego +4 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 0 - 50

Code: NCT05127226·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705

for Methylmalonic Acidemia

Sites in San Diego, Los Angeles & Palo Alto

Sponsor: ModernaTX, Inc.

Sex: All·Age: 1+

Code: NCT05295433·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for Peripheral Arterial Diseases

Sites in San Diego +8 more locations

Sponsor: Angiodynamics, Inc.

Sex: All·Age: All ages

Code: NCT06777901·Phase 4·Recruiting·Listed Jan 2025

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A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety

for Epileptic Encephalopathy

Sites in San Diego +5 more locations

Sponsor: Praxis Precision Medicines

Sex: All·Age: 1 Day - 18

Code: NCT07019922·Phase 3·Recruiting·Listed Jun 2025

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Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

for Age-Related Macular Degeneration

Sites in San Diego, Encino +5 more locations

Sponsor: Perceive Biotherapeutics, Inc.

Sex: All·Age: 60+

Code: NCT06087458·Phase 1, Phase 2·Recruiting·Listed Oct 2023

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ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

for Locally Advanced Solid Tumor

Sites in San Diego +3 more locations

Sponsor: Acepodia Biotech, Inc.

Sex: All·Age: 18+

Code: NCT06415487·Phase 1·Recruiting·Listed May 2024

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CERAMENT G Device Registry

for Chronic Osteomyelitis

Sites in San Diego +2 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT06010433·Recruiting·Listed Aug 2023

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Pan-tumor MRD Study

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in San Diego +1 more location

Sponsor: Paradigm Health

Sex: All·Age: 18+

Code: NCT06605404·Recruiting·Listed Sep 2024

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ExoLuminate Study for Early Detection of Pancreatic Cancer

for Pancreas Cancer

1 location in San Diego

Sponsor: Biological Dynamics

Sex: All·Age: 18+

Code: NCT05625529·Recruiting·Listed Nov 2022

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The Use of Residual De-identified Specimens and/or Samples From Patients for Clinical Research

for Hematologic Diseases

1 location in San Diego

Sponsor: Invivoscribe, Inc.

Sex: All·Age: 18+

Code: NCT06222164·Recruiting·Listed Jan 2024

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Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury

for Insomnia

1 location in San Diego

Sponsor: Noctem, LLC

Sex: All·Age: 18+

Code: NCT06867666·Recruiting·Listed Mar 2025

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Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

for Long Term Follow-up

Sites in San Diego +2 more locations

Sponsor: Arbutus Biopharma Corporation

Sex: All·Age: 20 - 70

Code: NCT06277037·Recruiting·Listed Feb 2024

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A Multicenter Study in Bronchoscopy Combining Stimulated Raman Histology With Artificial Intelligence for Rapid Lung Cancer Detection - The ON-SITE Study

for Lung Biopsy

Sites in San Diego +4 more locations

Sponsor: Invenio Imaging Inc.

Sex: All·Age: 22+

Code: NCT07045103·Recruiting·Listed Jul 2025

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A Beta-only IL-2 ImmunoTherapY Study

for Advanced Solid Tumor

Sites in San Diego, Santa Monica +3 more locations

Sponsor: Medicenna Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05086692·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees

for Amputation of Lower Limb

Sites in San Diego & La Jolla

Sponsor: LIMBER Prosthetics & Orthotics Inc

Sex: All·Age: 18 - 75

Code: NCT06648798·Recruiting·Listed Oct 2024

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A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery

for Surgery

1 location in San Diego

Sponsor: Alume Biosciences, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06662097·Phase 2·Recruiting·Listed Oct 2024

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Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction

for Congestive Heart Failure

Sites in San Diego, San Francisco +3 more locations

Sponsor: Sardocor Corp.

Sex: All·Age: 18 - 80

Code: NCT04703842·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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Mindfulness Engaged Neurostimulation for Depression (MEND II)

for Depression

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 65

Code: NCT07512284·Phase 2·Recruiting·Listed Apr 2026

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Continued Pressure for Alveolar Protection (CPAP Trial)

for Bronchopulmonary Dysplasia (BPD)

Sites in San Diego, Palo Alto +13 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: Up to 31 Weeks

Code: NCT07417111·Recruiting·Listed Feb 2026

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Predicting Pre-dementia

for Mild Cognitive Impairment (MCI)

1 location in San Diego

Sponsor: Prevention Research Consortium Corp.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT07516119·Recruiting·Listed Apr 2026

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Sleep Health in U.S. Marines

for Depression

1 location in San Diego

Sponsor: San Diego State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07420205·Phase 2·Recruiting·Listed Feb 2026

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Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection

for Cystic Fibrosis (CF)

Sites in San Diego +1 more location

Sponsor: Ghady Haidar

Sex: All·Age: 18+

Code: NCT07275905·Phase 1·Recruiting·Listed Dec 2025

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Blood Pressure Care for Advancing Real-World Evidence (BPCARE)

for Hypertension

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 21+

Code: NCT07398391·Recruiting·Listed Feb 2026

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Vancomycin in TKAs

for Total Knee Arthroplasty

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07282782·Phase 4·Recruiting·Listed Dec 2025

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Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain

for Gulf War Illness

1 location in San Diego

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18 - 65

Code: NCT07325513·Recruiting·Listed Jan 2026

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in San Diego, La Jolla +637 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in San Diego, San Marcos +1103 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Endotype DIrected Treatment for OSA in Down Syndrome

for Obstructive Sleep Apnea (OSA)

Sites in San Diego +4 more locations

Sponsor: University of Arizona

Sex: All·Age: 6+

Code: NCT07280468·Phase 4·Recruiting·Listed Dec 2025

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Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

for HIV-1-infection

Sites in San Diego, Los Angeles +9 more locations

Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07293559·Recruiting·Listed Dec 2025

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in San Diego, La Jolla +920 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

Sites in San Diego, La Jolla +288 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in San Diego, La Jolla +583 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in San Diego, San Marcos +299 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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Mobile Health for Adherence in Breast Cancer Patients

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in San Diego, San Marcos +457 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06112613·Recruiting·Listed Nov 2023

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

Sites in San Diego, La Jolla +385 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting·Listed Mar 2017

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Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

for Adenocarcinoma of the Colon

Sites in San Diego, San Marcos +363 more locations

Sponsor: NRG Oncology

Sex: All·Age: 45 - 70

Code: NCT05080673·Recruiting·Listed Oct 2021

Apply to this trial