Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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Healthy volunteers only

1,109 clinical trials

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

for Breast Cancer

Sites in Charleston +14 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04468061·Phase 2·Recruiting·Listed Jul 2020

Apply to this trial

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

Sites in Charleston +58 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting·Listed Dec 2022

Apply to this trial

Weight Loss and ExeRcise for Post-stroke Veterans

for Stroke

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 80

Code: NCT06322030·Recruiting·Listed Mar 2024

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OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

Sites in Charleston +6 more locations

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting·Listed Apr 2025

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COAST Therapy in Advanced Solid Tumors and Prostate Cancer

for Prostate Cancer Recurrent

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05036226·Phase 1, Phase 2·Recruiting·Listed Sep 2021

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Development of an mHealth Behavioral Sleep Medicine Intervention for Use During Medication Assisted Treatment for MOUD

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06157840·Recruiting·Listed Dec 2023

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Risk Adapted De-Intensification of Radio-Chemotherapy for Oropharyngeal Squamous Cell Carcinoma

for Oropharyngeal Squamous Cell Carcinoma

Sites in Charleston +2 more locations

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05268614·Phase 2·Recruiting·Listed Mar 2022

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NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

for Triple Negative Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06845319·Phase 2·Recruiting·Listed Feb 2025

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Establishing Mobile Transcranial Magnetic Stimulation

for Treatment Resistant Major Depression

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 22 - 80

Code: NCT06748209·Phase 4·Recruiting·Listed Dec 2024

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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Charleston, Greenville +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Greenville, Greer +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement

for Knee Replacement

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+

Code: NCT06768762·Recruiting·Listed Jan 2025

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Charleston, Greenville +143 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

for Oropharyngeal Squamous Cell Carcinoma

Sites in North Charleston +1 more location

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT04564989·Recruiting·Listed Sep 2020

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An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

Sites in Charleston, Greenville +147 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting·Listed Jul 2020

Apply to this trial

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

Sites in Charleston, Greenville +81 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting·Listed Dec 2022

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Charleston +31 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

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Integration of Cognitive Processing Therapy and Relapse Prevention for Alcohol Use Disorder and PTSD

for Posttraumatic Stress Disorder

Sites in Charleston +1 more location

Sponsor: Texas A&M University

Sex: All·Age: 18+

Code: NCT05959434·Phase 2·Recruiting·Listed Jul 2023

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Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

for Post-Traumatic Stress Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 7 - 18

Code: NCT06332209·Recruiting·Listed Mar 2024

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Greenville +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

Apply to this trial

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

Sites in Greenville, Spartanburg +194 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting·Listed Oct 2023

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Safety and Efficacy of Mesenchymal Stem Cells Associated With Chronic Pancreatitis Pain

for Chronic Pancreatitis

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 75

Code: NCT06205342·EARLY_Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

RTMS Targets Neural Circuits for Smoking Cessation

for Tobacco Use

2 locations in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 22 - 70·Accepts healthy volunteers

Code: NCT04903028·Recruiting·Listed May 2021

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Autologous Mesenchymal Stromal Cells and Islet Co-transplantation in TP-IAT

for Chronic Pancreatitis

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT05095532·Phase 1·Recruiting·Listed Oct 2021

Apply to this trial

iAmHealthy Clinical Practice Guideline (CPG)

for Pediatric Obesity

Sites in Charleston +3 more locations

Sponsor: University of Kansas Medical Center

Sex: All·Age: 6 - 11

Code: NCT06888011·Recruiting·Listed Mar 2025

Apply to this trial

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

Sites in Greenville, Spartanburg +140 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting·Listed Jun 2019

Apply to this trial

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

for Obesity

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 35 - 85

Code: NCT05901675·Recruiting·Listed Jun 2023

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A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

for High-Risk Prostate Cancer

Sites in Charleston +4 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05593497·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

HVIP Outcomes and Stakeholder Insights

for Firearm Injury

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT06582953·Recruiting·Listed Sep 2024

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A Brief Intervention for Cannabis Use

for Cannabis Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18 - 25

Code: NCT06395389·Recruiting·Listed May 2024

Apply to this trial

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

Sites in Florence +147 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting·Listed Mar 2021

Apply to this trial

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

for Tobacco Use

Sites in Charleston, Greenville +2 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06922617·Recruiting·Listed Apr 2025

Apply to this trial

Novel Cellular Therapy for the Treatment of Pain Associated With Chronic Pancreatitis

for Chronic Pancreatitis

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05925036·Phase 1·Recruiting·Listed Jun 2023

Apply to this trial

Cannabis-Tobacco Co-Use Treatment Study

for Tobacco Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06883162·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial

MEP Up-conditioning to Target Corticospinal Plasticity

for Spinal Cord Injury

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06989905·EARLY_Phase 1·Recruiting·Listed May 2025

Apply to this trial

Dose Response of Exercise for Arthritis Management

for Arthritis

1 location in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+

Code: NCT06880653·Recruiting·Listed Mar 2025

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Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

for Alcohol Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT05786157·Recruiting·Listed Mar 2023

Apply to this trial

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

Sites in Charleston +10 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting·Listed Dec 2024

Apply to this trial

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in Columbia, Mt. Pleasant +71 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

for Amblyopia

Sites in Columbia +67 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 3 - 13

Code: NCT04378790·Phase 3·Recruiting·Listed May 2020

Apply to this trial