Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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Comparing Standard of Care Biopsy System to a Novel Biopsy Needle System by Computational Pathologic Analysis

for Prostate Cancer Screening

Sites in Hardeeville +1 more location

Sponsor: Uro-1 Medical

Sex: Male·Age: 18+

Code: NCT06830265·Recruiting·Listed Feb 2025

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Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

for Hypereosinophilic Syndrome

Drug: Depemokimab

Sites in Charleston +5 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05334368·Phase 3·Recruiting·Listed Apr 2022

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Charleston, Bluffton +327 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

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Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

for Angioimmunoblastic T-cell Lymphoma

Sites in Charleston +85 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT04803201·Phase 2·Recruiting·Listed Mar 2021

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A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (GLOBALIGHT)

for Dry Age-related Macular Degeneration

Sites in Charleston +5 more locations

Sponsor: LumiThera, Inc.

Sex: All·Age: All ages

Code: NCT06351605·Recruiting·Listed Apr 2024

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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

Sites in Greenville +35 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting·Listed Nov 2022

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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

for Prostate Cancer

Drug: Saruparib

Sites in Myrtle Beach +36 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18+

Code: NCT06952803·Phase 3·Recruiting·Listed May 2025

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

Sites in Charleston, Columbia +115 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06742723·Phase 3·Recruiting·Listed Dec 2024

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A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

for COPD (Chronic Obstructive Pulmonary Disease)

Sites in Charleston, Spartanburg +132 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06283966·Phase 3·Recruiting·Listed Feb 2024

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

Sites in Summerville +54 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting·Listed Dec 2024

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Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency

for Growth Hormone Deficiency (GHD)

Sites in Columbia +29 more locations

Sponsor: Lumos Pharma

Sex: All·Age: 3 - 11

Code: NCT06948214·Phase 3·Recruiting·Listed Apr 2025

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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

Sites in Columbia +83 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting·Listed Dec 2005

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Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for Transthyretin Amyloidosis

Sites in Greenville +32 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06465810·Recruiting·Listed Jun 2024

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Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Greenville +30 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT06467357·Phase 3·Recruiting·Listed Jun 2024

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

Sites in Charleston +45 more locations

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting·Listed Jun 2025

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Personalized Brain Stimulation to Help Veterans Quit Smoking

for Tabacco Use Disorder

1 location in Charleston

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 70

Code: NCT07050862·Recruiting·Listed Jul 2025

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Alleviant ALLAY-HFrEF Study

for Heart Failure

Sites in Charleston +38 more locations

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 18+

Code: NCT06812533·Recruiting·Listed Feb 2025

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Alleviant ALLAY-HF Study

for Heart Failure

Sites in Charleston, Colombia +41 more locations

Sponsor: Alleviant Medical, Inc.

Sex: All·Age: 40+

Code: NCT05685303·Recruiting·Listed Jan 2023

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Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for Asthma

Sites in Charleston +95 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12 - 17

Code: NCT06307665·Phase 3·Recruiting·Listed Mar 2024

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An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

for Hyperkalaemia

Sites in Columbia +3 more locations

Sponsor: AstraZeneca

Sex: All·Age: 0 - 18

Code: NCT03813407·Phase 3·Recruiting·Listed Jan 2019

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for Non-Small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Greenville +48 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06357533·Phase 3·Recruiting·Listed Apr 2024

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Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: IMVT-1402

Sites in Charleston +47 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 80

Code: NCT07039916·Phase 3·Recruiting·Listed Jun 2025

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PSMA PET Combined With MRI for the Detection of PCa

for PCA

Sites in Myrtle Beach +15 more locations

Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT07052214·Phase 3·Recruiting·Listed Jul 2025

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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

for Heart Failure

Drug: Dapagliflozin

Sites in Columbia, Spartanburg +175 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT06677060·Phase 3·Recruiting·Listed Nov 2024

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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

for Pulmonary Arterial Hypertension

Sites in Charleston +28 more locations

Sponsor: Gossamer Bio USA, Inc.

Sex: All·Age: 18 - 75

Code: NCT06274801·Phase 3·Recruiting·Listed Feb 2024

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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

for Binge-Eating Disorder

Drug: Solriamfetol

Sites in Greenville, North Charleston +36 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 55

Code: NCT06413433·Phase 3·Recruiting·Listed May 2024

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

Sites in Columbia, Spartanburg +66 more locations

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting·Listed Feb 2025

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Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)

for Excessive Sleepiness

Drug: Solriamfetol

Sites in Charleston, Columbia +39 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06568367·Phase 3·Recruiting·Listed Aug 2024

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

Sites in Rock Hill +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting·Listed Apr 2025

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

Sites in Charleston +49 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting·Listed Jan 2025

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A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism

for Primary Hyperaldosteronism

Drug: Baxdrostat

Sites in Columbia +2 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07007793·Phase 3·Recruiting·Listed Jun 2025

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A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

for Solid Tumor

Sites in Myrtle Beach +15 more locations

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18+

Code: NCT06874335·Phase 1·Recruiting·Listed Mar 2025

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A Trial to Evaluate the Efficacy and Safety of Tralokinumab in Combination With Topical Corticosteroids in Children and Infants With Moderate-to-severe Atopic Dermatitis

for Atopic Dermatitis

Sites in Charleston +13 more locations

Sponsor: LEO Pharma

Sex: All·Age: 6 Months - 11

Code: NCT06311682·Phase 3·Recruiting·Listed Mar 2024

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Product Surveillance Registry

for Cardiac Rhythm Disorders

Sites in Charleston, Columbia +127 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting·Listed Feb 2012

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Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

for APOL1-Mediated Kidney Disease

Sites in Columbia, Spartanburg +76 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT06824987·Phase 2·Recruiting·Listed Feb 2025

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Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS

for Acute Coronary Syndrome

Sites in Spartanburg, Rock Hill +146 more locations

Sponsor: DalCor Pharmaceuticals

Sex: All·Age: 45+

Code: NCT05918861·Phase 3·Recruiting·Listed Jun 2023

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Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

for Delayed Graft Function

Sites in Greenville +29 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06830798·Phase 3·Recruiting·Listed Feb 2025

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Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

for Insomnia Disorder

Sites in Columbia, Myrtle Beach +18 more locations

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06953869·Phase 3·Recruiting·Listed May 2025

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Efficacy and Safety Study of OATD-01 in Patients With Active Pulmonary Sarcoidosis

for Pulmonary Sarcoidosis

Sites in Charleston +3 more locations

Sponsor: Molecure S.A.

Sex: All·Age: 18+

Code: NCT06205121·Phase 2·Recruiting·Listed Jan 2024

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A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

Sites in Charleston, Greenville +48 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial