Paid Clinical Trials in South Carolina

South Carolina has 1,277 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

1,277 clinical trials

↓ Download CSV

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

for Chronic Pain

7 locations incl. Greenwood

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07190807·Recruiting

Apply to this trial

Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

for Osteoarthritis Knee Pain

20 locations incl. San Diego

Sponsor: Saol Therapeutics Inc

Sex: All·Age: 40+

Code: NCT07226258·Phase 3·Recruiting

Apply to this trial

Development of Optical Biometer

for Cataract and IOL Surgery

1 location in Hilton Head Island

Sponsor: Cassini Technologies

Sex: All·Age: 18+

Code: NCT07325162·Recruiting

Apply to this trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

148 locations incl. Loma Linda

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for Bronchiectasis With Pseudomonas Aeruginosa Colonization

25 locations incl. Orange

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07088926·Phase 2·Recruiting

Apply to this trial

Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Brivekimig

15 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07170917·Phase 2·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

for Non-muscle Invasive Bladder Cancer

39 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07206225·Phase 1·Recruiting

Apply to this trial

Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

for Opioid Use Disorder

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18 - 45

Code: NCT06999811·Recruiting

Apply to this trial

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for Neovascular Age-related Macular Degeneration

Drug: Surabgene Lomparvovec

53 locations incl. Mesa

Sponsor: AbbVie

Sex: All·Age: 50+

Code: NCT07007065·Phase 3·Recruiting

Apply to this trial

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

261 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting

Apply to this trial

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

for Wound Healing and Prevention

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07095556·Recruiting

Apply to this trial

Examining Whether Project Support Works

for Parent-Child Relations

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 6 - 13

Code: NCT06963554·Recruiting

Apply to this trial

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

for Nonsegmental Vitiligo

Drug: Zasocitinib

23 locations incl. Bryant

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT07108283·Phase 2·Recruiting

Apply to this trial

Motoneuron Recruitment and Motor Evoked Potential Up-Conditioning (MEP) in Spinal Cord Injury (SCI)

for Spinal Cord Injuries and Disorders (SCI/D)

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07179822·Recruiting

Apply to this trial

A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

for Smoking

Drug: Brenipatide

16 locations incl. Rogers

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07223840·Phase 2·Recruiting

Apply to this trial

A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa (HS)

31 locations incl. Phoenix

Sponsor: Bluefin Biomedicine, Inc.

Sex: All·Age: 18 - 75

Code: NCT07287644·Phase 2, Phase 3·Recruiting

Apply to this trial

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

for Congenital Diaphragmatic Hernia

19 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 Months - 1 Month

Code: NCT05213676·Phase 4·Recruiting

Apply to this trial

SAINT in Postpartum Depression (PPD)

for Postpartum Depression (PPD)

4 locations incl. Worcester

Sponsor: Magnus Medical

Sex: Female·Age: 18 - 45

Code: NCT07210255·Recruiting

Apply to this trial

Closed-loop rTMS-EEG During Visuomotor Integration.

for Visuomotor Skills

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07249801·Recruiting

Apply to this trial

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

20 locations incl. San Jose

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting

Apply to this trial

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

50 locations incl. Chandler

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting

Apply to this trial

Preoperative Acetazolamide

for Post Operative Pain

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 21 - 65

Code: NCT07101250·Phase 4·Recruiting

Apply to this trial

Intracervical Vasopressin

for Retained Products of Conception

1 location in Greenville

Sponsor: Prisma Health-Upstate

Sex: Female·Age: 18 - 51

Code: NCT07102615·Phase 4·Recruiting

Apply to this trial

A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

for Bronchiectasis

14 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 85

Code: NCT07201051·Phase 2·Recruiting

Apply to this trial

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

for Prostate Cancer Patients Treated by Radiotherapy

7 locations incl. Peoria

Sponsor: Candel Therapeutics, Inc.

Sex: Male·Age: 18+

Code: NCT07332000·Phase 2·Recruiting

Apply to this trial

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

for Meniere's Disease

9 locations incl. Los Angeles

Sponsor: Sound Pharmaceuticals, Incorporated

Sex: All·Age: 18 - 75

Code: NCT06859788·Phase 3·Recruiting

Apply to this trial

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

for Geographic Atrophy (GA)

27 locations incl. Gilbert

Sponsor: ONL Therapeutics

Sex: All·Age: 55+

Code: NCT06659445·Phase 2·Recruiting

Apply to this trial

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

40 locations incl. Birmingham

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting

Apply to this trial

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

for Cardiac Failure

7 locations incl. Los Angeles

Sponsor: Inova Health Care Services

Sex: All·Age: 18 - 99

Code: NCT06939751·Recruiting

Apply to this trial

Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

for Unilateral Vocal Cord Paralysis

10 locations incl. La Jolla

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07579364·Enrolling By Invitation

RaDIANT Health Systems Intervention

for End Stage Renal Disease (ESRD)

5 locations incl. Atlanta

Sponsor: Indiana University

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07033117·Recruiting

Apply to this trial

Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain

for Lower Back Pain

2 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07166952·Recruiting

Apply to this trial

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

for Ovarian Neoplasms

83 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213804·Phase 3·Recruiting

Apply to this trial

NeoCARD: Anthracycline-Free Neoadjuvant Chemoimmunotherapy in Triple-Negative Breast Cancer Patients

for Triple Negative Breast Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06845319·Phase 2·Recruiting

Apply to this trial

Evaluating the Long-term Safety and Tolerability of Imatinib in Patients With Lymphangioleiomyomatosis (LAM)

for Lymphangioleiomyomatosis (LAM)

2 locations incl. New York

Sponsor: Columbia University

Sex: Female·Age: 18 - 64

Code: NCT06889168·Phase 1·Recruiting

Apply to this trial

Proof of Concept Study to Assess the Pharmacokinetics/Pharmacodynamics of Nemolizumab in Adults With Chronic Pruritus of Unknown Origin (CPUO)

for Chronic Pruritus of Unknown Origin

Drug: Nemolizumab

25 locations incl. Birmingham

Sponsor: Galderma R&D

Sex: All·Age: 18+

Code: NCT07074977·Phase 2·Recruiting

Apply to this trial

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

for Tobacco Use

4 locations incl. Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT06922617·Recruiting

Apply to this trial

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

376 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting

Apply to this trial

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

for Metabolic Dysfunction-Associated Steatotic Liver Disease

140 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07165028·Phase 3·Recruiting

Apply to this trial

Long-Term Stability of the Glide Control Strategy

for Upper Limb Amputation Above Elbow

10 locations incl. Annapolis

Sponsor: Infinite Biomedical Technologies

Sex: All·Age: 18+

Code: NCT07222085·Recruiting

Apply to this trial