Paid Clinical Trials in South Carolina

South Carolina has 1,217 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,101 clinical trials

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A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

for Pneumococcal Disease

Sites in Simpsonville +20 more locations

Sponsor: Pfizer

Sex: All·Age: 42 Days - 98 Days·Accepts healthy volunteers

Code: NCT07573462·Phase 3·Recruiting·Listed May 2026

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AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Spartanburg +13 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

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A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Teclistamab

Sites in Greenville +34 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07518186·Phase 3·Recruiting·Listed Apr 2026

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A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

Sites in Charleston +9 more locations

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting·Listed Apr 2026

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A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

Sites in Charleston, Columbia +38 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting·Listed Mar 2026

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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

Sites in Summerville +17 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting·Listed Mar 2026

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Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Greenville +16 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

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A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis, Generalized

Sites in Charleston +14 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18+

Code: NCT07501702·Phase 2·Recruiting·Listed Mar 2026

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A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in North Charleston +18 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07481630·Phase 3·Recruiting·Listed Mar 2026

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Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for Non-Arteritic Anterior Ischemic Optic Neuropathy

Sites in Charleston +21 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 50 - 80

Code: NCT07453888·Phase 3·Recruiting·Listed Mar 2026

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A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

for Sleep Apnea, Obstructive

Drug: Eloralintide

Sites in Columbia +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07369011·Phase 3·Recruiting·Listed Jan 2026

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Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

for Atrial Fibrillation (AF)

Sites in Anderson +17 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07430956·Phase 3·Recruiting·Listed Feb 2026

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A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

for Narcolepsy

Sites in Columbia +16 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT07493265·Phase 2·Recruiting·Listed Mar 2026

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Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

Sites in Greenville +28 more locations

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting·Listed Jan 2026

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A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

for Non-Muscle Invasive Bladder Neoplasms

Sites in North Charleston +16 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07309445·Recruiting·Listed Dec 2025

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Pivotal Study of the SUpira System in Patients Undergoing High-Risk Percutaneous COronaRy InTervention (HRPCI)

for Coronary Artery Disease

Sites in Columbia +18 more locations

Sponsor: Supira Medical

Sex: All·Age: 18 - 90

Code: NCT07296744·Recruiting·Listed Dec 2025

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AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

for Obesity

Drug: NNC0487-0111

Sites in Charleston, North Charleston +20 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07339423·Phase 3·Recruiting·Listed Jan 2026

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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)

for Severe Asthma

Drug: GB-0895

Sites in Rock Hill +19 more locations

Sponsor: Generate Biomedicines

Sex: All·Age: 12 - 80

Code: NCT07359846·Phase 3·Recruiting·Listed Jan 2026

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Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma

for Low Grade Upper Tract Urothelial Carcinoma

Sites in Mt. Pleasant +18 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT07265947·Phase 2·Recruiting·Listed Dec 2025

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A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

Sites in Greenville +19 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting·Listed Dec 2025

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A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

for Plaque Psoriasis

Drug: Zasocitinib

Sites in Charleston +10 more locations

Sponsor: Takeda

Sex: All·Age: 4 - 17

Code: NCT07250802·Phase 3·Recruiting·Listed Nov 2025

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Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

for Pneumococcal Immunization

Sites in Charleston, Spartanburg +11 more locations

Sponsor: Sanofi

Sex: All·Age: 42 Days - 89 Days·Accepts healthy volunteers

Code: NCT07348692·Phase 3·Recruiting·Listed Jan 2026

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A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

for Advanced Renal Cell Carcinoma (RCC)

Drug: Pumitamig

Sites in Charleston, Myrtle Beach +15 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07293351·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

for Obesity

Sites in Mauldin +23 more locations

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284875·Phase 3·Recruiting·Listed Dec 2025

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Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain

for Osteoarthritis Knee Pain

Sites in Charleston, Greenville +20 more locations

Sponsor: Saol Therapeutics Inc

Sex: All·Age: 40+

Code: NCT07226258·Phase 3·Recruiting·Listed Nov 2025

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Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma

for Clear Cell Renal Cell Carcinoma

Sites in Myrtle Beach +11 more locations

Sponsor: Neomorph, Inc

Sex: All·Age: 18+

Code: NCT07300241·Phase 1·Recruiting·Listed Dec 2025

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A Study of Brenipatide in Adults Who Quit Smoking Cigarettes and Want to Avoid Relapse

for Smoking

Drug: Brenipatide

Sites in North Charleston +16 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07223840·Phase 2·Recruiting·Listed Nov 2025

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A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)

for Focal Segmental Glomerulosclerosis

Sites in Goose Creek +23 more locations

Sponsor: Akebia Therapeutics

Sex: All·Age: 18+

Code: NCT07268638·Phase 2·Recruiting·Listed Dec 2025

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AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

for Corneal Edema

Sites in Ladson +11 more locations

Sponsor: Aurion Biotech

Sex: All·Age: 18+

Code: NCT07368959·Phase 3·Recruiting·Listed Jan 2026

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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

for Primary Membranous Nephropathy

Sites in Greenville, Spartanburg +24 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 75

Code: NCT07204275·Phase 2, Phase 3·Recruiting·Listed Oct 2025

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

Sites in Greenville +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting·Listed Nov 2025

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Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Brivekimig

Sites in Myrtle Beach +14 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07170917·Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

for Clonal Mast Cell Disease

Sites in Charleston +21 more locations

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07143669·Recruiting·Listed Aug 2025

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Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

Sites in Greenville +14 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting·Listed Dec 2024

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FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Charleston, Greenville +8 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

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Abbott Cephea Mitral Valve Disease Registry

for Mitral Regurgitation

Sites in Charleston +23 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07069673·Recruiting·Listed Jul 2025

Apply to this trial

A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

for Macular Edema

Sites in Greenville +37 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06962839·Phase 2·Recruiting·Listed May 2025

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A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

for Obesity

Sites in Charleston +50 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 6 - 17

Code: NCT06672549·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

Sites in Greenville +15 more locations

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting·Listed Dec 2022

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4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

for Neovascular (Wet) Age-Related Macular Degeneration

Sites in West Columbia +19 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT05197270·Phase 1, Phase 2·Recruiting·Listed Jan 2022

Apply to this trial