Paid Clinical Trials in South Carolina

South Carolina has 1,226 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

1,109 clinical trials

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Drug: Vosoritide

Sites in Columbia +30 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06382155·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

Metastatic Castrate-Resistant Prostate Cancer Subjects Treated With PROVENGE® + One Infusion of Sipuleucel-T

for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Sites in Charleston, Myrtle Beach +28 more locations

Sponsor: Dendreon

Sex: Male·Age: 18+

Code: NCT06134232·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

Sites in Myrtle Beach, Rock Hill +25 more locations

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting·Listed Sep 2021

Apply to this trial

A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

Sites in Charleston, Columbia +83 more locations

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

for Spinal Muscular Atrophy (SMA)

Sites in Greenville +41 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04174157·Recruiting·Listed Nov 2019

Apply to this trial

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

Sites in Greenville +66 more locations

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting·Listed Mar 2018

Apply to this trial

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

Sites in Greenville, West Columbia +118 more locations

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting·Listed May 2023

Apply to this trial

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumors

Sites in Charleston, Greenville +26 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05914116·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Evaluation of SPN-812 (Viloxazine Extended-release Capsule) in Preschool-age Children With ADHD

for Attention-Deficit/Hyperactivity Disorder

Sites in North Charleston, Summerville +45 more locations

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 48 Months - 69 Months

Code: NCT04781140·Phase 4·Recruiting·Listed Mar 2021

Apply to this trial

Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Columbia +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

Apply to this trial

Efficacy of Fusidic Acid 1% in the Treatment of Bacterial Conjunctivitis

for Bacterial Conjunctivitis

Sites in Charleston, Greenville +19 more locations

Sponsor: Baxis Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT06911424·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

for Locally Advanced Pancreatic Cancer

Sites in Greenville +14 more locations

Sponsor: RenovoRx

Sex: All·Age: 18+

Code: NCT03257033·Phase 3·Recruiting·Listed Aug 2017

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

Sites in Charleston +36 more locations

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial

NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness

for Aortic Dissection

Sites in Charleston +23 more locations

Sponsor: Endospan Ltd.

Sex: All·Age: 18+

Code: NCT04471909·Recruiting·Listed Jul 2020

Apply to this trial

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

Sites in Charleston, Florence +34 more locations

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting·Listed Nov 2023

Apply to this trial

TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)

for Tricuspid Regurgitation

Sites in Charleston +35 more locations

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18+

Code: NCT06137807·Recruiting·Listed Nov 2023

Apply to this trial

MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

for In-Stent Restenosis

Sites in Greenville +27 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 18 - 110

Code: NCT05908331·Recruiting·Listed Jun 2023

Apply to this trial

C-Brace Prospective Registry

for Pareses

Sites in Spartanburg +36 more locations

Sponsor: Otto Bock Healthcare Products GmbH

Sex: All·Age: All ages

Code: NCT04640584·Recruiting·Listed Nov 2020

Apply to this trial

A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight

for Obesity

Sites in Greer +19 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 74

Code: NCT07662122·Phase 2·Recruiting·Listed Jun 23, 2026

Apply to this trial

Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder

for Cannabis Withdrawal

Sites in North Charleston +20 more locations

Sponsor: PleoPharma, Inc.

Sex: All·Age: 18 - 55

Code: NCT07644052·Phase 3·Recruiting·Listed Jun 12, 2026

Apply to this trial

Study of EVO756 in Adults With Migraine

for Migraine

Sites in Charleston +13 more locations

Sponsor: Evommune, Inc.

Sex: All·Age: 18 - 64

Code: NCT07616128·Phase 2·Recruiting·Listed Jun 2026

Apply to this trial

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Narcolepsy

for EDS

Sites in Charleston, Columbia +12 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07675135·Phase 3·Recruiting·Listed Jun 30, 2026

Apply to this trial

Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD

for Rhinovirus Infection

Sites in Rock Hill, Anderson +12 more locations

Sponsor: Altesa Biosciences, Inc.

Sex: All·Age: 40 - 85

Code: NCT07610395·Phase 2·Recruiting·Listed May 2026

Apply to this trial

Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

for Obesity

Sites in North Charleston +10 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07607587·Phase 1·Recruiting·Listed May 2026

Apply to this trial

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

Drug: NNC0487-0111

Sites in Columbia +19 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571109·Phase 3·Recruiting·Listed May 2026

Apply to this trial

A Study to Learn About the Safety of an Expanded Pneumococcal Vaccine in Healthy Infants

for Pneumococcal Disease

Sites in Simpsonville +18 more locations

Sponsor: Pfizer

Sex: All·Age: 42 Days - 98 Days·Accepts healthy volunteers

Code: NCT07573462·Phase 3·Recruiting·Listed May 2026

Apply to this trial

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

for Diabetes Mellitus

Drug: NNC0487-0111

Sites in Spartanburg +14 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07533175·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

for Alpha 1 Antitrypsin Deficiency

Sites in Charleston +9 more locations

Sponsor: Grifols Therapeutics LLC

Sex: All·Age: 18 - 80

Code: NCT07555483·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

A Phase 3 Efficacy and Safety Study of HBS-301 in Participants With Idiopathic Hypersomnia (IH)

for Idiopathic Hypersomnia

Sites in Charleston, Columbia +20 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 18+

Code: NCT07500090·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)

for Psoriatic Arthritis

Drug: Tulisokibart

Sites in Summerville +15 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 80

Code: NCT07486960·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Continuous Dual Aspiration Technique With Zoom System for Stroke

for Ischemic Stroke

Sites in Greenville +15 more locations

Sponsor: Imperative Care, Inc.

Sex: All·Age: 18+

Code: NCT07491952·Recruiting·Listed Mar 2026

Apply to this trial

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

for Obesity

Drug: NNC0487-0111

Sites in North Charleston +18 more locations

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07481630·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis, Generalized

Sites in Charleston +13 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT07501702·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults

for Influenza

Sites in Anderson +9 more locations

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07496450·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

for Atrial Fibrillation (AF)

Sites in Anderson +17 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07430956·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy

for Narcolepsy

Sites in Columbia +16 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT07493265·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

for Non-Arteritic Anterior Ischemic Optic Neuropathy

Sites in Charleston +17 more locations

Sponsor: Dompé Farmaceutici S.p.A

Sex: All·Age: 50 - 80

Code: NCT07453888·Phase 3·Recruiting·Listed Mar 2026

Apply to this trial

A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

for Moderate to Severe Glabellar Lines

Drug: IPN10200

Sites in Charleston +16 more locations

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT07427797·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

for Sleep Apnea, Obstructive

Drug: Eloralintide

Sites in Columbia +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07369011·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

for Glioblastoma (GBM)

Sites in Greenville +21 more locations

Sponsor: Black Diamond Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07326566·Phase 2·Recruiting·Listed Jan 2026

Apply to this trial