Solid tumor Clinical Trials in Seattle, WA
As of September 2026, 52 paid clinical trials are recruiting for Solid tumor in Seattle, Washington. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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52 clinical trials for Solid tumor
·Clear filters·The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
SLV-154 Treatment of Advanced Cancers
Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
First in Human Study of TUB-030 in Patients With Advanced Solid Tumors
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
A Clinical Study of YL205 in Patients With Advanced Solid Tumors
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
A Study of KK2269 in Adult Participants With Solid Tumors
An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors
A Study of BGB-B455 in Adults With Advanced or Metastatic Solid Tumors
SMP-3124LP in Adults With Advanced Solid Tumors
A First-in-Human (FIH) Study of BG-C137, an Anti-Fibroblast Growth Factor Receptor 2b (FGFR2b) Antibody Drug Conjugate, in Participants With Advanced Solid Tumors
A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer
Project: Every Child for Younger Patients With Cancer
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes
Telephone-Based Coaching Sessions (TAC) to Improve Advance Care Planning Participation in Advanced Cancer Patients and Their Support Person
Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
Top Research Study Locations in Seattle
Researchers run research studies in Seattle, WA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Seattle Children's Hospital | Diffuse Intrinsic Pontine Glioma, Cystic Fibrosis, High Grade Glioma | 185 |
| University of Washington | Amyotrophic Lateral Sclerosis, Spinal Cord Injuries, Breast Cancer | 183 |
| Fred Hutchinson Cancer Center | Breast Cancer, Acute Myeloid Leukemia, Colorectal Cancer | 141 |
| Fred Hutch/University of Washington Cancer Consortium | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Stage IVB Prostate Cancer AJCC v8 | 104 |
| Swedish Medical Center-First Hill | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Malignant Solid Neoplasm | 65 |
| University of Washington Medical Center | Cystic Fibrosis, Heart Diseases, Heart Transplant | 50 |
| University of Washington Medical Center - Montlake | Prostate Adenocarcinoma, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 39 |
| Fred Hutchinson Cancer Research Center | Chronic Lymphocytic Leukemia, Advanced Solid Tumor, Chronic Graft-versus-host-disease | 36 |
| Swedish Cancer Institute | Breast Cancer, Endometrial Cancer, Chronic Lymphocytic Leukemia | 34 |
| Swedish Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 32 |
| Virginia Mason Medical Center | Breast Cancer, Colorectal Cancer, Hearing Loss, Unilateral | 31 |
| Swedish Medical Center-Ballard Campus | Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Ovarian Carcinoma | 30 |
| Swedish Medical Center-Cherry Hill | Malignant Solid Neoplasm, Hematopoietic and Lymphoid Cell Neoplasm, Ovarian Carcinoma | 29 |
| Harborview Medical Center | Spinal Cord Injuries, Urothelial Carcinoma, Abdominal Aortic Aneurysms | 20 |
| VA Puget Sound Health Care System Seattle Division, Seattle, WA | Obesity, Adult Growth Hormone Deficiency, Advanced Urothelial Carcinoma | 20 |
| Seattle Children's | Suicidal Ideation, Acute Kidney Injury, Becker Muscular Dystrophy | 16 |
| FHCC at Northwest Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 14 |
| Fred Hutch Cancer Center | Colorectal Cancer, Advanced Adenocarcinoma, Astrocytoma, Grade IV | 11 |
| GSK Investigational Site | HIV Infections, Non-alcoholic Fatty Liver Disease, Gastrointestinal Neoplasms | 11 |
| VA Puget Sound Health Care System | Parkinson's Disease, Barrett's Esophagus, Carcinoma, Non-Small-Cell Lung | 11 |
| Benaroya Research Institute | Type 1 Diabetes Mellitus, Acute Pancreatitis, T1D | 9 |
| Seattle Children's Research Institute | ADA SCID, Adolescent Behavior, Brain Concussion | 8 |
| Seattle Clinical Research Center | Obesity, Overweight, Acute Migraine | 7 |
| Seattle Cancer Care Alliance | Acute Myeloid Leukemia, Breast Cancer, Chronic Myelomonocytic Leukemia | 6 |
| University of Washington - Harborview Medical Center | Aneurysm, Intracranial, Brain Aneurysm, CPAP | 6 |
Active & Upcoming Studies in Seattle (2026)
Recruiting trials in Seattle grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (486 active studies)
- Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial) · Phase 2 · National Cancer Institute (NCI)
- Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome · Phase 2 · Fred Hutchinson Cancer Center
Neurology & pain (62 active studies)
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
Diabetes & metabolic (59 active studies)
- METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) · Phase 2 · University of Washington
- Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS) · Phase 3 · Eli Lilly and Company
Cardiovascular (51 active studies)
- A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF) · Phase 2 · Edgewise Therapeutics, Inc.
- Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH) · Phase 2 · Stanford University
Mental health & behavior (28 active studies)
- VOCALE LBD: Online Peer Support for Caregivers of People With Lewy Body Dementia · University of Washington
- A Novel Smartphone Application for Helping Teens Stop Vaping, QuitQuest Vaping R01 · Fred Hutchinson Cancer Center
Pediatric (28 active studies)
- Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG). · Phase 2 · BrainChild Bio, Inc
- Mobile Technology to Reduce Teen Substance Misuse · Evidence-Based Practice Institute, Seattle, WA
HIV / STI (15 active studies)
- Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults · Seattle Institute for Biomedical and Clinical Research
- A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan Antibodies · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (12 active studies)
- A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age · Phase 3 · GlaxoSmithKline
- A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age · Phase 2 · ModernaTX, Inc.
Eye & vision (2 active studies)
- Disulfiram for Treatment of Retinal Degeneration · Phase 1, Phase 2 · University of Washington
- The Myelin Disorders Biorepository Project · Children's Hospital of Philadelphia
Common conditions studied in Seattle
- Acute Myeloid Leukemia (34 active studies)
- Breast Cancer (20 active studies)
- Colorectal Cancer (20 active studies)
- Ovarian Cancer (16 active studies)
- Prostate Cancer (14 active studies)
- Chronic Lymphocytic Leukemia (13 active studies)
Leading research sponsors in Seattle
- University of Washington
- Fred Hutchinson Cancer Center
- National Cancer Institute (NCI)
- Seattle Children's Hospital
- AstraZeneca
Frequently asked questions
How many paid clinical trials are currently recruiting in Seattle?
There are approximately 1,286 recruiting clinical trials in Seattle, Washington listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Seattle pay participants?
Most recruiting trials in Seattle compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Seattle?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Seattle?
The most common conditions under active study in Seattle include Acute Myeloid Leukemia (34), Breast Cancer (20), Colorectal Cancer (20), Ovarian Cancer (16), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Seattle?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Seattle on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Seattle?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Seattle?
Recruiting research sites in Seattle include Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Seattle right now?
The largest active categories in Seattle are Cancer & tumors (486), Neurology & pain (62), Diabetes & metabolic (59). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.