Paid Clinical Trials in St Louis, MO

As of September 2026, 1,422 paid clinical trials are recruiting in St Louis, Missouri. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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1,287 clinical trials

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DORA and LP in Alzheimer's Disease Biomarkers

for Alzheimer Disease

1 location in St Louis

Sponsor: University of Minnesota

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06274528·Phase 2·Recruiting·Listed Feb 2024

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Aging, Geriatric Syndromes and Clonal Hematopoiesis

for Geriatrics

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT02604563·Recruiting·Listed Nov 2015

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Sleep Trial to Prevent Alzheimer's Disease

for Sleep

1 location in St Louis

Sponsor: University of Minnesota

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT04629547·Phase 2·Recruiting·Listed Nov 2020

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Migraine in Adolescents

for Migraine

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 10 - 13·Accepts healthy volunteers

Code: NCT05654012·Recruiting·Listed Dec 2022

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Examining Racial and Socioeconomic Differences in Chronic Low Back Pain

for Chronic Pain

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 85

Code: NCT05991440·Recruiting·Listed Aug 2023

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Sex Hormones, Postoperative Pain and Opioid Use

for Postoperative Pain

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 11 - 16

Code: NCT06023225·Recruiting·Listed Sep 2023

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Endometriosis Pain

for Pelvic Pain

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 12 - 45

Code: NCT06101303·Recruiting·Listed Oct 2023

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Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

Sites in St Louis +30 more locations

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting·Listed Apr 2025

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The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial

for Extubation Failure

Sites in St Louis, Kansas City +14 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 0 Days - 9 Weeks

Code: NCT05446272·Recruiting·Listed Jul 2022

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

Sites in St Louis, Kansas City +21 more locations

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting·Listed Jan 2023

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in St Louis +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma

for Multiple Myeloma

Drug: Selinexor

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07200102·Phase 1·Recruiting·Listed Sep 2025

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in St Louis, Ballwin +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

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Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma

for Multiple Myeloma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06185751·Phase 1·Recruiting·Listed Dec 2023

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Auricular VNS Following Intracerebral Hemorrhage

for Intracerebral Hemorrhage

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06799390·Recruiting·Listed Jan 2025

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Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT04968964·Recruiting·Listed Jul 2021

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in St Louis +32 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

Sites in St Louis +21 more locations

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting·Listed May 2023

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Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

for Atrial Fibrillation

Sites in St Louis +2 more locations

Sponsor: Tulane University

Sex: All·Age: 40 - 120

Code: NCT05014802·Recruiting·Listed Aug 2021

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INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients

for Surgery

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 60+

Code: NCT07283783·Recruiting·Listed Dec 2025

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in St Louis, Creve Coeur +36 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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Testing Adaptive Interventions to Improve Posttraumatic Stress Disorder Treatment Outcomes in Federally Qualified Health Centers

for PTSD

Sites in St Louis +11 more locations

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05457985·Recruiting·Listed Jul 2022

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Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

for Glioblastoma Multiforme

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT05864976·Recruiting·Listed May 2023

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Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

for Deep Venous Thrombosis

Sites in St Louis +19 more locations

Sponsor: Yale University

Sex: All·Age: Up to 17

Code: NCT04924322·Phase 2, Phase 3·Recruiting·Listed Jun 2021

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Risk Reducing Salpingectomy With Delayed Oophorectomy as an Alternative to Risk- Reducing Salpingo-oophorectomy in High Risk-Women to Assess the Safety of Prevention - US Cohort Study

for Ovarian Cancer

Sites in St Louis +8 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT05287451·Recruiting·Listed Mar 2022

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SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

for Epithelioid Hemangioendothelioma (EHE)

Sites in St Louis +5 more locations

Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All·Age: 18+

Code: NCT07104331·Phase 2·Recruiting·Listed Aug 2025

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Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

for Acute Myeloid Leukemia

Sites in St Louis, Creve Coeur +17 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06484062·Phase 1·Recruiting·Listed Jul 2024

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in St Louis, Lee's Summit +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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Registry Study for Radiation Therapy Outcomes

for Neoplasms

Sites in St Louis +28 more locations

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting·Listed Dec 2010

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64Cu-LLP2A for Imaging Hematologic Malignancies

for Multiple Myeloma

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06636175·EARLY_Phase 1·Recruiting·Listed Oct 2024

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Sensory Optimization of the Hospital Environment

for Preterm

1 location in St Louis

Sponsor: University of Southern California

Sex: All·Age: 1 Day - 7 Days

Code: NCT05230199·Recruiting·Listed Feb 2022

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ALS/MND Natural History Study Data Repository

for ALS

Sites in St Louis +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in St Louis +59 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in St Louis +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

Sites in St Louis +21 more locations

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting·Listed Feb 2022

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Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

for Childhood Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 7 - 17

Code: NCT05582551·Recruiting·Listed Oct 2022

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Horizon Two: HR NDMM (MMRC-100)

for High Risk Newly Diagnosed Multiple Myeloma

Sites in St Louis +6 more locations

Sponsor: Multiple Myeloma Research Consortium

Sex: All·Age: 18+

Code: NCT07053436·Phase 2·Recruiting·Listed Jul 2025

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Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders

for Severe Sickle Cell Disease

Sites in St Louis +3 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 1 Day - 21

Code: NCT03128996·Phase 1, Phase 2·Recruiting·Listed Apr 2017

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in St Louis, Creve Coeur +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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ChatGPT & Surgeon Synergy: Redefining Breast Reconstruction Consultations for Enhanced Patient Engagement and Satisfaction

for Breast Cancer

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06981208·Recruiting·Listed May 2025

Apply to this trial