Paid Clinical Trials in Tennessee

Tennessee has 2,062 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,839 clinical trials

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Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

for Duchenne Muscular Dystrophy (DMD)

Sites in Nashville +8 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07674758·Recruiting·Listed Jun 2026

Apply to this trial

Deformable Tissue Modelling and Augmented Reality Based Guidance for Head and Neck Tumor Re-Resection Task

for Physician

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07686211·EARLY_Phase 1·Recruiting·Listed Jul 2026

Apply to this trial

Bereaved Parent Conversations on Hope

for Hope

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07675083·Recruiting·Listed Jun 2026

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PRecision Integrated Saturation Monitor

for CHD - Congenital Heart Disease

1 location in Memphis

Sponsor: Le Bonheur Children's Hospital

Sex: All·Age: 0 Months - 12 Months

Code: NCT07686341·Recruiting·Listed Jul 2026

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Prospective Investigation of Cirrhotic Cardiomyopathy in Humans

for Cirrhotic Cardiomyopathy

Sites in Nashville +1 more location

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07658222·Recruiting·Listed Jun 2026

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Neural Basis of Human Working Memory

for Memory Disorders

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07617506·Recruiting·Listed Jun 2026

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Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

for Myopia

Sites in Memphis +12 more locations

Sponsor: Ohio State University

Sex: All·Age: 6 - 11·Accepts healthy volunteers

Code: NCT07567040·Phase 3·Recruiting·Listed May 2026

Apply to this trial

Collaboration for Down Syndrome Progress (CDP)

for Down Syndrome

Sites in Memphis +15 more locations

Sponsor: RTI International

Sex: All·Age: All ages

Code: NCT07625579·Recruiting·Listed Jun 2026

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Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS)

for Lumbar Puncture

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 1 Day - 12 Months

Code: NCT07612644·Recruiting·Listed May 2026

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ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

Sites in Nashville +16 more locations

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903·Recruiting·Listed Apr 2026

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Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the Circulation

for Liver Transplant

Sites in Nashville +9 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 3 - 13

Code: NCT07549503·Phase 2·Recruiting·Listed Apr 2026

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Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors

for Survivors of Childhood Cancer

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 15+

Code: NCT07516301·Recruiting·Listed Apr 2026

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Impact of Pelvic Pain Podcast

for Chronic Pelvic Pain

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Female·Age: 18+

Code: NCT07568834·Recruiting·Listed May 2026

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Suction vs Underwater Seal for HemoPneumoThoraX Trial

for Hemothorax

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07551791·Recruiting·Listed Apr 2026

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Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension

for Pulmonary Hypertension

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 85

Code: NCT07563322·Recruiting·Listed May 2026

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Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

for Breast Cancer (Triple Negative Breast Cancer (TNBC))

1 location in Nashville

Sponsor: Jessica Mezzanotte Sharpe

Sex: All·Age: 18+

Code: NCT07555210·Recruiting·Listed Apr 2026

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Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Ribociclib

Sites in Memphis, Collierville +171 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)

for Acute Uncomplicated Diverticulitis

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 90

Code: NCT07492134·Phase 2·Recruiting·Listed Mar 2026

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Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease

for PARKINSON DISEASE (Disorder)

1 location in Johnson City

Sponsor: East Tennessee State University

Sex: All·Age: All ages

Code: NCT07551661·Recruiting·Listed Apr 2026

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Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

for Sarcoma, Bone

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 5 - 20·Accepts healthy volunteers

Code: NCT07502885·Recruiting·Listed Mar 2026

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Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures

for Meningioma

1 location in Nashville

Sponsor: Eben Rosenthal

Sex: All·Age: 18+

Code: NCT07493447·EARLY_Phase 1·Recruiting·Listed Mar 2026

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Vanderbilt Integrated Community TMS for Opioid Recovery

for Opiod Use Disorder

Sites in Nashville & Brentwood

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT07457489·Recruiting·Listed Mar 2026

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PrP-targeting siRNA Safety & Mechanism Study

for Prion Disease

Sites in Nashville +4 more locations

Sponsor: Broad Institute of MIT and Harvard

Sex: All·Age: 18+

Code: NCT07444580·Phase 1·Recruiting·Listed Mar 2026

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Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Memphis, Collierville +204 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 65+

Code: NCT07321652·Phase 3·Recruiting·Listed Jan 2026

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Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma

for Pediatric Osteosarcoma

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 21

Code: NCT07428993·Phase 2·Recruiting·Listed Feb 2026

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Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

Sites in Memphis, Collierville +346 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting·Listed Dec 2025

Apply to this trial

Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

for Essential Tremor, Movement Disorders

Sites in Memphis +3 more locations

Sponsor: CND Life Sciences

Sex: All·Age: 50 - 85

Code: NCT07428447·Recruiting·Listed Feb 2026

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Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)

for Hnscc

Drug: Nivolumab

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT07460765·Phase 1·Recruiting·Listed Mar 2026

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Rehabilitation With Empowered STrategies to Optimize REcovery

for Lumbar Spine Degenerative Changes

Sites in Nashville +3 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 85

Code: NCT07406997·Recruiting·Listed Feb 2026

Apply to this trial

Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia

for Fibromuscular Dysplasia of Arteries

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 100

Code: NCT07529691·Recruiting·Listed Apr 2026

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Outcomes of Health Care Transition for AYA With a Cancer Predisposition

for Genetic Predisposition

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 18+

Code: NCT07456904·Recruiting·Listed Mar 2026

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Endoscopic COlorectal Mucosal Evaluation of Oxygen Tension

for Anastomotic Leak Rectum

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07467980·Recruiting·Listed Mar 2026

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

Sites in Nashville +6 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting·Listed Feb 2026

Apply to this trial

Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer

for Advanced Clear Cell Renal Cell Carcinoma

Sites in Memphis, Collierville +39 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT07383441·Phase 3·Recruiting·Listed Feb 2026

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Exogenous Ketone Supplementation in ICU Delirium

for ICU Delirium

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07364162·Phase 2·Recruiting·Listed Jan 2026

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A Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After Treatment

for Lung Non-Small Cell Carcinoma

Sites in Memphis, Collierville +95 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07293247·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

Sites in Nashville +15 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for Type III Achalasia

Sites in Nashville +15 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293689·Recruiting·Listed Dec 2025

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Memphis, Knoxville +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Clinical Performance of Verofilcon A Toric Contact Lenses

for Contact Lenses

1 location in Memphis

Sponsor: Southern College of Optometry

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07586982·Recruiting·Listed May 2026

Apply to this trial