Paid Clinical Trials in Tennessee

Tennessee has 2,159 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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2,159 clinical trials

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Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

for Hepatocellular Carcinoma

12 locations incl. Beverly Hills

Sponsor: Replimune, Inc.

Sex: All·Age: 18+

Code: NCT05733598·Phase 2·Recruiting

Apply to this trial

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

for Traumatic Brain Injury

18 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT05826912·Phase 2·Enrolling By Invitation

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

for Head and Neck Squamous Cell Carcinoma

29 locations incl. Duarte

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06163534·Recruiting

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VTP-1000 in Adults With Celiac Disease

for Celiac Disease

16 locations incl. Los Angeles

Sponsor: Barinthus Biotherapeutics

Sex: All·Age: 18 - 70

Code: NCT06310291·EARLY_Phase 1·Recruiting

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Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

for Advanced Breast Cancer

Drug: Camizestrant

54 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06380751·Phase 3·Recruiting

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Text-messaging Intervention to Support Parents After Their Child's Psychiatric Emergency

for Parents

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06456762·Recruiting

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A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

for Generalized Myasthenia Gravis

Drug: Iptacopan

21 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT06517758·Phase 3·Recruiting

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Long-term Safety and Tolerability of BHV-7000

for Focal Epilepsy

115 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06443463·Phase 2·Enrolling By Invitation

Investigations of Reproductive Cancers in Women

for Uterine Cancer

16 locations incl. Birmingham

Sponsor: PinkDx, Inc.

Sex: Female·Age: 45 - 100

Code: NCT06527157·Recruiting

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Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

for Differentiated Thyroid Cancer

4 locations incl. Philadelphia

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 25

Code: NCT06458036·Phase 2·Recruiting

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The APS Phenotyping Study

for ARDS

20 locations incl. Fresno

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06521502·Recruiting

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JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

for Solid Tumors

7 locations incl. Denver

Sponsor: Jacobio Pharmaceuticals Co., Ltd.

Sex: All·Age: 18+

Code: NCT06386146·Phase 1, Phase 2·Recruiting

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A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors

for Metastatic Hepatocellular Carcinoma

Drug: Bevacizumab

7 locations incl. Goodyear

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06427941·Phase 1·Recruiting

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A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

for Extensive Stage-small Cell Lung Cancer

Drug: Atezolizumab

26 locations incl. Birmingham

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06362252·Phase 1, Phase 2·Recruiting

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A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

87 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting

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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

for Cancer

6 locations incl. Los Angeles

Sponsor: Angiex, Inc.

Sex: All·Age: 18+

Code: NCT06440005·Phase 1·Recruiting

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An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumors

11 locations incl. Los Angeles

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 18+

Code: NCT06480552·Phase 1·Recruiting

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Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

for Biliary Tract Cancer

21 locations incl. Duarte

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06282575·Phase 3·Recruiting

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QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

for Acute Kidney Injury

15 locations incl. Birmingham

Sponsor: SeaStar Medical

Sex: All·Age: Up to 22

Code: NCT06517810·Recruiting

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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

for Inflammatory Bowel Diseases

25 locations incl. Lancaster

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Sex: All·Age: 18 - 85

Code: NCT06226883·Phase 2·Recruiting

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A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

17 locations incl. Irvine

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting

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Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for Metastatic Colorectal Cancer

Drug: Bevacizumab

26 locations incl. Chandler

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT06252649·Phase 3·Recruiting

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Daily Eating Patterns for Total Health Study

for Obesity

1 location in Knoxville

Sponsor: The University of Tennessee, Knoxville

Sex: All·Age: 25 - 60

Code: NCT06455995·Recruiting

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Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)

for Essential Thrombocythemia

22 locations incl. Glendale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06456346·Phase 3·Recruiting

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A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

for Hepatocellular Carcinoma

Drug: Atezolizumab

60 locations incl. Tucson

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06096779·Phase 2·Recruiting

Apply to this trial

Embo Registry; National Registry for Artery Embolization

for Chronic Pain

2 locations incl. Cary

Sponsor: Vascular Solutions of North Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06477965·Recruiting

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Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

for Regional Citrate Anticoagulation (RCA)

14 locations incl. Birmingham

Sponsor: Vantive Health LLC

Sex: All·Age: 18+

Code: NCT05399537·Phase 3·Recruiting

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Galleri® in the Medicare Population.

for Cancer

61 locations incl. Fort Smith

Sponsor: GRAIL, Inc.

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT05673018·Recruiting

Apply to this trial

Opioid Prescribing Practices in Laparoscopic Gynecologic Surgery

for Opioid Use

1 location in Memphis

Sponsor: University of Tennessee

Sex: Female·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06532708·Recruiting

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

50 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting

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Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery

for Resectable Intrahepatic Cholangiocarcinoma

Drug: Durvalumab

58 locations incl. Irvine

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06050252·Phase 2·Recruiting

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Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim

for Duchenne Muscular Dystrophy

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: Male·Age: 10+

Code: NCT06093100·Recruiting

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A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors

for Platinum-resistant Ovarian Cancer

13 locations incl. Little Rock

Sponsor: Context Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06515613·Phase 1·Recruiting

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Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

22 locations incl. Los Angeles

Sponsor: Servier Bio-Innovation LLC

Sex: All·Age: 18+

Code: NCT06127407·Phase 3·Recruiting

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A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

7 locations incl. Sacramento

Sponsor: Avistone Biotechnology Co., Ltd.

Sex: All·Age: 18+

Code: NCT06046495·Phase 1·Recruiting

Apply to this trial

Low-Dose Ketamine Infusion During Burn Wound Care

for Burn

1 location in Memphis

Sponsor: University of Tennessee

Sex: All·Age: 18+

Code: NCT06506565·Phase 4·Recruiting

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Continuation Protocol for Obstructive Sleep Apnea (OSA)

for OSA

93 locations incl. Birmingham

Sponsor: Apnimed

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06566820·Phase 3·Enrolling By Invitation

From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

for Foot Injury

5 locations incl. San Diego

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65

Code: NCT06352788·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

for Solid Tumors

18 locations incl. Birmingham

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06431594·Phase 1·Recruiting

Apply to this trial