Paid Clinical Trials in Tennessee

Tennessee has 2,062 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,839 clinical trials

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

Sites in Nashville, Memphis +115 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting·Listed Nov 2019

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Nashville, Memphis +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

Sites in Nashville, Memphis +73 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting·Listed Oct 2023

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Nashville, Knoxville +167 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Nashville, Memphis +151 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

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Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

for Type 1 Diabetes Mellitus

Sites in Nashville +13 more locations

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 8 - 45

Code: NCT07142252·Phase 2·Recruiting·Listed Aug 2025

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

Sites in Nashville +21 more locations

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Nashville, Memphis +170 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

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Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for Buccal Mucosa Squamous Cell Carcinoma

Sites in Nashville, Memphis +85 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04333537·Phase 2, Phase 3·Recruiting·Listed Apr 2020

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Nashville, Memphis +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Nashville, Memphis +43 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

for Genetic Disease

Sites in Nashville +26 more locations

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 1 Month - 100·Accepts healthy volunteers

Code: NCT02450851·Recruiting·Listed May 2015

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

Sites in Memphis, Collierville +948 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019

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Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

Sites in Nashville +5 more locations

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127·Recruiting·Listed Nov 2025

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Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry

for Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease

Sites in Nashville +38 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT01915511·Recruiting·Listed Aug 2013

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A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

for Basal Ganglia Germinoma

Sites in Nashville, Memphis +93 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT06368817·Phase 2·Recruiting·Listed Apr 2024

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Nashville, Memphis +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Nashville, Memphis +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Nashville, Memphis +141 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Sites in Nashville, Knoxville +37 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 25

Code: NCT07022678·Phase 3·Recruiting·Listed Jun 2025

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Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage

for End Stage Chronic Renal Failure

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07385651·Recruiting·Listed Feb 2026

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PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

for Infections

Sites in Nashville +12 more locations

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18+

Code: NCT05699174·Phase 3·Recruiting·Listed Jan 2023

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Nashville, Memphis +139 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Memphis, Collierville +370 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022

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Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

for Core Binding Factor Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Memphis, Collierville +59 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT06917911·Phase 2·Recruiting·Listed Apr 2025

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Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Drug: Omalizumab

Sites in Nashville +20 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 40+

Code: NCT07059091·Phase 2·Recruiting·Listed Jul 2025

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ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

Sites in Nashville +45 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting·Listed May 2021

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CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

for Diffuse Midline Glioma, H3 K27-Altered

Sites in Memphis +32 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 21

Code: NCT04870944·Phase 1, Phase 2·Recruiting·Listed May 2021

Apply to this trial

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

for Cardiac Arrest, Out-Of-Hospital

Sites in Memphis +48 more locations

Sponsor: University of Michigan

Sex: All·Age: 2 Days - 17

Code: NCT05376267·Recruiting·Listed May 2022

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Rapid Evacuation and Access of Cerebral Hemorrhage Trial

for Stroke Hemorrhagic

Sites in Nashville +23 more locations

Sponsor: Emory University

Sex: All·Age: 18 - 70

Code: NCT06870812·Recruiting·Listed Mar 2025

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Knoxville +41 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

for B Acute Lymphoblastic Leukemia Associated With Down Syndrome

Sites in Nashville, Memphis +70 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 - 39

Code: NCT05702645·Recruiting·Listed Jan 2023

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Evaluation Of Cardiovascular Health Outcomes Among Survivors 2

for Health Behavior

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 26+

Code: NCT07245420·Recruiting·Listed Nov 2025

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A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Advanced Renal Cell Carcinoma (aRCC)

Drug: Cemiplimab

Sites in Nashville +4 more locations

Sponsor: Brian Rini

Sex: All·Age: 18+

Code: NCT07188896·Phase 2·Recruiting·Listed Sep 2025

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Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

for Astrocytoma, IDH-Mutant, Grade 2

Sites in Nashville +34 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06860594·Phase 1·Recruiting·Listed Mar 2025

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Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure

for Aortic Stenosis

1 location in Knoxville

Sponsor: University of Tennessee Graduate School of Medicine

Sex: All·Age: 18+

Code: NCT07205068·Recruiting·Listed Oct 2025

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

for Gastric Adenocarcinoma

Sites in Nashville +77 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT07001748·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

Sites in Memphis +9 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting·Listed Aug 2025

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A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

for Childhood Medulloblastoma

Sites in Knoxville +101 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 4 - 21

Code: NCT05382338·Phase 3·Recruiting·Listed May 2022

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Nashville +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

Apply to this trial