Paid Clinical Trials in Tupelo, MS
As of August 2026, 32 paid clinical trials are recruiting in Tupelo, Mississippi. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Tupelo offers studies at sites including North Mississippi Medical Center for conditions such as Cardiovascular Diseases, Coronary Artery Disease, Atrial Fibrillation, Hypertension. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Tupelo
Trials by drug in Tupelo
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Newly added in Tupelo
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
31 clinical trials
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Drug-Eluting Registry: Real-World Treatment of Lesions in the Peripheral Vasculature
SELUTION 4 De Novo Small Vessel IDE Trial
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
The CONFORM Pivotal Trial
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
SPYRAL GEMINI Pilot Study
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
EVERO Drug-coated Balloon (DCB) Randomized Trial
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)
A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease
Effect of Dalcetrapib on CV Risk in a Genetically Defined Population With a Recent ACS
Top Research Study Locations in Tupelo
Researchers run research studies in Tupelo, MS at 18 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| North Mississippi Medical Center | Cardiovascular Diseases, Coronary Artery Disease, Atrial Fibrillation | 7 |
| North Mississippi Hematology and Oncology Associates | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 3 |
| Cardiology Associates Research, LLC | Cardiovascular Diseases, Coronary Artery Disease, In-Stent Restenosis | 2 |
| Cardiology Associates of North Mississippi | Atherosclerotic Cardiovascular Disease, Obesity, Overweight | 2 |
| - Nephrology and Hypertension Associates Ltd | End Stage Kidney Disease | 1 |
| Cardiolg Assoc Rsch LLC_Tupelo | Acute Myocardial Infarction (AMI), Cardiovascular Risk | 1 |
| Cardiology Associates Research | Acute Myocardial Infarction | 1 |
| Cardiology Associates Research LLC | Cardiovascular Disease | 1 |
| Cardiology Associates of North MS | Atrial Fibrillation | 1 |
| Clinical Trial Site | High Cardiovascular Risk, High Risk Cardiovascular Disease, Hypertension | 1 |
| Digestive Health Specialists | Ulcerative Colitis | 1 |
| Nephrology & Hypertension Associates Ltd - Tupelo | Chronic Kidney Disease, Receiving Dialysis, Dialysis, ESRD (End-Stage Renal Disease) | 1 |
| Nephrology & Hypertension Associates, Ltd. | Focal Segmental Glomerulosclerosis | 1 |
| Nephrology and Hypertension Associates - Tupelo | Proteinuric Kidney Disease | 1 |
| North Mississippi Health Services | Lung Cancer Screening | 1 |
| SOG Surgery Center | Lumbar Spinal Stenosis | 1 |
| Tupelo, MS Investigative | Acute Heart Failure, Heart Failure | 1 |
| Xencor Investigative Site | Ulcerative Colitis (UC) | 1 |
Active & Upcoming Studies in Tupelo (2026)
Recruiting trials in Tupelo grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cardiovascular (10 active studies)
- A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation · Phase 2 · Novartis Pharmaceuticals
- Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease · Phase 3 · Alnylam Pharmaceuticals
Cancer & tumors (2 active studies)
- Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System in Nevada and Mississippi: State-Based Initiative Component · Timothy Mullett
- A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer · Phase 3 · Eli Lilly and Company
Diabetes & metabolic (2 active studies)
Neurology & pain (1 active study)
- The CONFORM Pivotal Trial · Conformal Medical, Inc
Common conditions studied in Tupelo
- Cardiovascular Diseases (3 active studies)
- Coronary Artery Disease (3 active studies)
- Atrial Fibrillation (2 active studies)
- Hypertension (2 active studies)
- Neoplasm Metastasis (2 active studies)
- Proteinuric Kidney Disease (2 active studies)
Leading research sponsors in Tupelo
- Eli Lilly and Company
- Amgen
- AstraZeneca
- Concept Medical Inc.
- Alebund Pharmaceuticals
Frequently asked questions
How many paid clinical trials are currently recruiting in Tupelo?
There are approximately 32 recruiting clinical trials in Tupelo, Mississippi listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Tupelo pay participants?
Most recruiting trials in Tupelo compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Tupelo?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Tupelo?
The most common conditions under active study in Tupelo include Cardiovascular Diseases (3), Coronary Artery Disease (3), Atrial Fibrillation (2), Hypertension (2), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Tupelo?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Tupelo on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Tupelo?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Tupelo?
Recruiting research sites in Tupelo include North Mississippi Medical Center, North Mississippi Hematology and Oncology Associates, Cardiology Associates Research, LLC, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Tupelo right now?
The largest active categories in Tupelo are Cardiovascular (10), Cancer & tumors (2), Diabetes & metabolic (2). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.