Oncology Clinical Trials in Tyler, TX

As of August 2026, 55 paid clinical trials are recruiting for Oncology in Tyler, Texas. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

55 clinical trials for Oncology

·Clear filters·

Email me when a new oncology trial opens in Tyler, TX.

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

for Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Tyler, Bedford +16 more locations

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18+

Code: NCT07549412·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Tyler, Houston +13 more locations

Sponsor: BioNTech SE

Sex: Male·Age: 18+

Code: NCT07365995·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Tyler +12 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

Apply to this trial

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

for Endometrial Cancer

Sites in Tyler +8 more locations

Sponsor: Aadi Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05997017·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

Sites in Tyler +8 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting·Listed Nov 2021

Apply to this trial

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

for Colon Cancer

Sites in Tyler, Beaumont +12 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

for Multiple Myeloma

Drug: Talquetamab

Sites in Tyler, Austin +14 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05972135·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies

for B-cell Lymphoma

Sites in Tyler +5 more locations

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07520006·Phase 1, Phase 2·Recruiting·Listed Apr 2026

Apply to this trial

A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: ABBV-706

Sites in Tyler, Houston +28 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07365241·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in Tyler, Houston +65 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for Solid Tumor

Drug: INBRX-106

Sites in Tyler +12 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 18+

Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019

Apply to this trial

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Drug: Rilvegostomig

Sites in Tyler, Houston +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06921785·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Tyler, Plano +34 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

for Neoplasms

Sites in Tyler, Dallas +13 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06551142·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

Sites in Tyler, Kingwood +28 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06679101·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Oncology Clinical Trials in Tyler, TX

55 clinical trials for Oncology

Conditions in Oncology (Tyler, TX)