MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
for Lumbar Spinal Stenosis
Sites in Tyler, Longview +2341 more locations
Sponsor: Stryker Instruments
Sex: All·Age: 18+
Code: NCT03072927·Recruiting·Listed Mar 2017
Paid Clinical Trials in Tyler, TX
As of July 2026, 153 paid clinical trials are recruiting in Tyler, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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147 clinical trials
A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab
for Atopic Dermatitis
Drug: Upadacitinib
Sites in Tyler, Mesquite +64 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 63
Code: NCT06389136·Phase 3·Recruiting·Listed Apr 2024
A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
for Carcinoma, Non-Small-Cell Lung
Drug: Adagrasib
Sites in Tyler, Dallas +48 more locations
Sponsor: Mirati Therapeutics Inc.
Sex: All·Age: 18+
Code: NCT06875310·Phase 3·Recruiting·Listed Mar 2025
A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer
for Low Grade Serous Ovarian Cancer
Drug: Avutometinib
Sites in Tyler, Fort Worth +36 more locations
Sponsor: Verastem, Inc.
Sex: Female·Age: 18+
Code: NCT06072781·Phase 3·Recruiting·Listed Oct 2023
A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
for Ovarian Cancer
Drug: INCB123667
Sites in Tyler, Austin +36 more locations
Sponsor: Incyte Corporation
Sex: Female·Age: 18 - 99
Code: NCT07023627·Phase 2·Recruiting·Listed Jun 2025
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
for Ulcerative Colitis
Drug: Duvakitug
Sites in Tyler, Southlake +89 more locations
Sponsor: Sanofi
Sex: All·Age: 16 - 80
Code: NCT07184996·Phase 3·Recruiting·Listed Sep 2025
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
for Chronic Lymphocytic Leukemia
Drug: Sonrotoclax
Sites in Tyler, Dallas +36 more locations
Sponsor: BeOne Medicines
Sex: All·Age: 18+
Code: NCT06943872·Phase 3·Recruiting·Listed Apr 2025
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
for Carcinoma, Non-Small-Cell Lung
Drug: Intismeran autogene
Sites in Tyler, Dallas +47 more locations
Sponsor: Merck Sharp & Dohme LLC
Sex: All·Age: 18+
Code: NCT06623422·Phase 3·Recruiting·Listed Oct 2024
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for Moderately to Severely Active Crohns Disease
Drug: Afimkibart
Sites in Tyler, Mesquite +90 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 16 - 80
Code: NCT06819878·Phase 3·Recruiting·Listed Feb 2025
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
for Non-Small Cell Lung Cancer
Drug: Divarasib
Sites in Tyler, Fort Worth +48 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 18+
Code: NCT06793215·Phase 3·Recruiting·Listed Jan 2025
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
for Bronchiectasis
Sites in Tyler, San Antonio +31 more locations
Sponsor: Boehringer Ingelheim
Sex: All·Age: 12+
Code: NCT06872892·Phase 3·Recruiting·Listed Mar 2025
A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
for Multiple Myeloma
Drug: Etentamig
Sites in Tyler, Dallas +25 more locations
Sponsor: AbbVie
Sex: All·Age: 18+
Code: NCT05650632·Phase 1·Recruiting·Listed Dec 2022
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
for High Grade Epithelial Ovarian Cancer
Sites in Tyler, Dallas +35 more locations
Sponsor: Genmab
Sex: All·Age: 18+
Code: NCT05579366·Phase 1, Phase 2·Recruiting·Listed Oct 2022
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
for Leukemia, Myeloid, Acute
Drug: Venetoclax
Sites in Tyler, Dallas +49 more locations
Sponsor: Janssen Research & Development, LLC
Sex: All·Age: 18+
Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025
A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
for Ulcerative Colitis
Drug: Tofacitinib
Sites in Tyler, Dallas +37 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 65
Code: NCT06095128·Phase 4·Recruiting·Listed Oct 2023
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer
for Breast Cancer
Sites in Tyler, Longview +132 more locations
Sponsor: Pfizer
Sex: All·Age: 18+
Code: NCT06966453·Phase 1, Phase 2·Recruiting·Listed May 2025
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
for Ulcerative Colitis
Sites in Tyler, Houston +44 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 75
Code: NCT06598943·Phase 2·Recruiting·Listed Sep 2024
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
for Crohn's Disease
Sites in Tyler, Mansfield +54 more locations
Sponsor: AbbVie
Sex: All·Age: 18 - 75
Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
for Crohn's Disease
Drug: Ustekinumab
Sites in Tyler, Dallas +40 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 70
Code: NCT06045754·Phase 4·Recruiting·Listed Sep 2023
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
for Ulcerative Colitis
Drug: Tirzepatide
Sites in Tyler, San Antonio +35 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 70
Code: NCT06937086·Phase 3·Recruiting·Listed Apr 2025
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
for Moderately to Severely Active Crohns Disease
Drug: Afimkibart
Sites in Tyler, Garland +50 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 16 - 80
Code: NCT06819891·Phase 3·Recruiting·Listed Feb 2025
The CONFORM Pivotal Trial
for Atrial Fibrillation
Sites in Tyler, Plano +64 more locations
Sponsor: Conformal Medical, Inc
Sex: All·Age: 18+
Code: NCT05147792·Recruiting·Listed Dec 2021
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
for Crohn's Disease
Drug: Tirzepatide
Sites in Tyler, San Antonio +33 more locations
Sponsor: Eli Lilly and Company
Sex: All·Age: 18 - 70
Code: NCT06937099·Phase 3·Recruiting·Listed Apr 2025
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
for Non-small Cell Lung Cancer
Drug: Relatlimab
Sites in Tyler, Houston +36 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT06561386·Phase 3·Recruiting·Listed Aug 2024
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
for Inflammatory Bowel Diseases
Sites in Tyler, Mansfield +23 more locations
Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Sex: All·Age: 18 - 85
Code: NCT06226883·Phase 2·Recruiting·Listed Jan 2024
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
for Moderately to Severely Active Ulcerative Colitis
Drug: Afimkibart
Sites in Tyler, Garland +68 more locations
Sponsor: Hoffmann-La Roche
Sex: All·Age: 16 - 80
Code: NCT06588855·Phase 3·Recruiting·Listed Sep 2024
Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System
for Persistent Atrial Fibrillation
Sites in Tyler, Austin +31 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT06735534·Recruiting·Listed Dec 2024
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
for Crohn's Disease
Drug: TAK-279
Sites in Tyler, Kingwood +24 more locations
Sponsor: Takeda
Sex: All·Age: 18 - 75
Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
for Heart Failure - NYHA II - IV
Sites in Tyler, Plano +33 more locations
Sponsor: Boston Scientific Corporation
Sex: All·Age: 18+
Code: NCT07069738·Recruiting·Listed Jul 2025
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
for Pulmonary Embolism
Sites in Tyler, The Woodlands +53 more locations
Sponsor: Penumbra Inc.
Sex: All·Age: 18+
Code: NCT04798261·Recruiting·Listed Mar 2021
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
for Breast Cancer
Sites in Tyler, Dallas +47 more locations
Sponsor: Greenwich LifeSciences, Inc.
Sex: All·Age: 18 - 100
Code: NCT05232916·Phase 3·Recruiting·Listed Feb 2022
A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer
for Small Cell Lung Cancer
Sites in Tyler, Houston +28 more locations
Sponsor: Daiichi Sankyo
Sex: All·Age: 18+
Code: NCT06203210·Phase 3·Recruiting·Listed Jan 2024
A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)
for Follicular Lymphoma
Drug: Golcadomide
Sites in Tyler, Fort Worth +29 more locations
Sponsor: Celgene
Sex: All·Age: 18+
Code: NCT06911502·Phase 3·Recruiting·Listed Apr 2025
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
for Non-Small Cell Lung Cancer
Drug: Ivonescimab
Sites in Tyler, Dallas +74 more locations
Sponsor: Summit Therapeutics
Sex: All·Age: 18+
Code: NCT05899608·Phase 3·Recruiting·Listed Jun 2023
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1
for Non-Small Cell Lung Cancer
Drug: Ivonescimab
Sites in Tyler, Dallas +92 more locations
Sponsor: Summit Therapeutics
Sex: All·Age: 18+
Code: NCT06767514·Phase 3·Recruiting·Listed Jan 2025
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
for Neovascular Age-Related Macular Degeneration (nAMD)
Sites in Tyler, Dallas +52 more locations
Sponsor: 4D Molecular Therapeutics
Sex: All·Age: 50+
Code: NCT07064759·Phase 3·Recruiting·Listed Jul 2025
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
Sites in Tyler, DeSoto +131 more locations
Sponsor: 89bio, Inc.
Sex: All·Age: 18 - 75
Code: NCT06419374·Phase 3·Recruiting·Listed May 2024
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Sites in Tyler, Garland +139 more locations
Sponsor: 89bio, Inc.
Sex: All·Age: 18 - 80
Code: NCT06318169·Phase 3·Recruiting·Listed Mar 2024
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
for Atrial Fibrillation (AF)
Drug: Abelacimab
Sites in Tyler, Greenville +131 more locations
Sponsor: Anthos Therapeutics, Inc.
Sex: All·Age: 65+
Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023
A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
for High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Sites in Tyler, Houston +32 more locations
Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Sex: Female·Age: 18+
Code: NCT05128825·Phase 2·Recruiting·Listed Nov 2021