Paid Clinical Trials in Tyler, TX

As of September 2026, 159 paid clinical trials are recruiting in Tyler, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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152 clinical trials

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A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for Ulcerative Colitis

Drug: Tofacitinib

Sites in Tyler, Dallas +35 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06095128·Phase 4·Recruiting·Listed Oct 2023

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A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

for Carcinoma, Non-Small-Cell Lung

Drug: Intismeran autogene

Sites in Tyler, Dallas +48 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06623422·Phase 3·Recruiting·Listed Oct 2024

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A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

for Ovarian Cancer

Drug: INCB123667

Sites in Tyler, Austin +36 more locations

Sponsor: Incyte Corporation

Sex: Female·Age: 18 - 99

Code: NCT07023627·Phase 2·Recruiting·Listed Jun 2025

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

Sites in Tyler, Dallas +47 more locations

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting·Listed Feb 2022

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

Sites in Tyler, Mesquite +91 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting·Listed Feb 2025

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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

for Crohn's Disease

Drug: Ustekinumab

Sites in Tyler, Dallas +39 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06045754·Phase 4·Recruiting·Listed Sep 2023

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

Drug: Venetoclax

Sites in Tyler, Dallas +54 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025

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Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

for Mesothelioma

Sites in Tyler, Dallas +20 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05245500·Phase 1·Recruiting·Listed Feb 2022

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A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

for Low Grade Serous Ovarian Cancer

Drug: Avutometinib

Sites in Tyler, Fort Worth +34 more locations

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT06072781·Phase 3·Recruiting·Listed Oct 2023

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

Drug: Afimkibart

Sites in Tyler, Garland +57 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819891·Phase 3·Recruiting·Listed Feb 2025

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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

for Ulcerative Colitis

Drug: Tirzepatide

Sites in Tyler, San Antonio +35 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937086·Phase 3·Recruiting·Listed Apr 2025

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Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

for Crohn's Disease

Drug: Tirzepatide

Sites in Tyler, San Antonio +33 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 70

Code: NCT06937099·Phase 3·Recruiting·Listed Apr 2025

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Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

for High Grade Epithelial Ovarian Cancer

Sites in Tyler, Dallas +35 more locations

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT05579366·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Tyler, Dallas +37 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06943872·Phase 3·Recruiting·Listed Apr 2025

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

Sites in Tyler, Houston +39 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting·Listed Aug 2024

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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

for Inflammatory Bowel Diseases

Sites in Tyler, Mansfield +23 more locations

Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Sex: All·Age: 18 - 85

Code: NCT06226883·Phase 2·Recruiting·Listed Jan 2024

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A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for Carcinoma, Non-Small Cell Lung

Drug: sigvotatug vedotin

Sites in Tyler, Irving +102 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04389632·Phase 1·Recruiting·Listed May 2020

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Sites in Tyler, Kingwood +24 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

Sites in Tyler, Garland +68 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting·Listed Sep 2024

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A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

for Ulcerative Colitis

Sites in Tyler, Houston +44 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT06598943·Phase 2·Recruiting·Listed Sep 2024

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Sites in Tyler, Houston +26 more locations

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting·Listed Aug 2024

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

Sites in Tyler, Plano +38 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting·Listed Jul 2025

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

Sites in Tyler, Austin +31 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting·Listed Dec 2024

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A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Drug: Etentamig

Sites in Tyler, Dallas +25 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05650632·Phase 1·Recruiting·Listed Dec 2022

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A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Tyler, Houston +28 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06203210·Phase 3·Recruiting·Listed Jan 2024

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A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

for Breast Cancer

Sites in Tyler, Longview +100 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07062965·Phase 3·Recruiting·Listed Jul 2025

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

Sites in Tyler, Mansfield +54 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

Sites in Tyler, Dallas +95 more locations

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting·Listed Jan 2025

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Sites in Tyler, DeSoto +131 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting·Listed May 2024

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A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

Sites in Tyler, Garland +136 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting·Listed Mar 2024

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

Sites in Tyler, The Woodlands +53 more locations

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting·Listed Mar 2021

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

Sites in Tyler, Greenville +131 more locations

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023

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A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

Sites in Tyler, Fort Worth +29 more locations

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting·Listed Apr 2025

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A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Sites in Tyler, Houston +32 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT05128825·Phase 2·Recruiting·Listed Nov 2021

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

Sites in Tyler, Dallas +52 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting·Listed Jul 2025

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Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohn Disease

Sites in Tyler, Garland +41 more locations

Sponsor: Abivax S.A.

Sex: All·Age: 18 - 75

Code: NCT06456593·Phase 2·Recruiting·Listed Jun 2024

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SELUTION4BTK Trial

for Peripheral Arterial Disease

Sites in Tyler, Houston +23 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05055297·Recruiting·Listed Sep 2021

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CCM OPEN HF Registry

for Heart Failure

Sites in Tyler, El Paso +26 more locations

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT07112924·Recruiting·Listed Aug 2025

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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

for Breast Cancer

Sites in Tyler, Longview +111 more locations

Sponsor: Agendia

Sex: All·Age: 18+

Code: NCT03053193·Recruiting·Listed Feb 2017

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A Study of Upadacitinib in Adult Participants With Moderate-to-Severe Atopic Dermatitis and Inadequate Response to Dupilumab

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Tyler, Mesquite +64 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 63

Code: NCT06389136·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial