Paid Clinical Trials in Tyler, TX

As of July 2026, 153 paid clinical trials are recruiting in Tyler, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

147 clinical trials

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

for Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

Drug: Botensilimab

Sites in Tyler, Dallas +4 more locations

Sponsor: Stingray Therapeutics

Sex: All·Age: 18+

Code: NCT06589440·Phase 2·Recruiting·Listed Sep 2024

Apply to this trial

First in Human Study of TORL-1-23 in Participants With Advanced Cancer

for Advanced Solid Tumor

Sites in Tyler +8 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT05103683·Phase 1·Recruiting·Listed Nov 2021

Apply to this trial

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

for Endometrial Cancer

Sites in Tyler +8 more locations

Sponsor: Aadi Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05997017·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

A Study of ETHIZIA Versus SURGICEL Original in Controlling Soft Tissue Bleeding During Open Surgery

for Hemostasis

Sites in Tyler +5 more locations

Sponsor: Ethicon, Inc.

Sex: All·Age: 22+

Code: NCT06664788·Recruiting·Listed Oct 2024

Apply to this trial

Study for Subjects With Relapsed/Refractory Non- Hodgkin Lymphoma

for Non Hodgkin's Lymphoma Refractory/Relapsed

Sites in Tyler +1 more location

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18+

Code: NCT05618925·Phase 1·Recruiting·Listed Nov 2022

Apply to this trial

Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

for Carcinoma, Non-Small-Cell Lung Cancer

Sites in Tyler +4 more locations

Sponsor: Kiromic BioPharma Inc.

Sex: All·Age: 18+

Code: NCT06069570·Phase 1·Recruiting·Listed Oct 2023

Apply to this trial

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

for Colon Cancer

Sites in Tyler, Beaumont +12 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Tyler, Dallas +45 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

Apply to this trial

Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

for Ototoxicity, Drug-Induced

Sites in Tyler +7 more locations

Sponsor: Kevin Winthrop

Sex: All·Age: 18 - 80

Code: NCT05730283·Phase 2·Recruiting·Listed Feb 2023

Apply to this trial

A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

for Heart Failure

Drug: Finerenone

Sites in Tyler, Denison +52 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06033950·Phase 3·Recruiting·Listed Sep 2023

Apply to this trial

Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

for Multiple Myeloma

Drug: Talquetamab

Sites in Tyler, Austin +14 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05972135·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

for Heart Failure With Reduced Ejection Fraction (HFrEF)

Sites in Tyler +12 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06964464·Phase 4·Recruiting·Listed May 2025

Apply to this trial

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for Epithelial Ovarian Cancer

Sites in Tyler, San Antonio +37 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07218809·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in Tyler, Houston +65 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

A Platform Study in Non-Small Cell Lung Cancer (NSCLC)

for Advanced or Metastatic Non-small Cell Lung Cancer

Sites in Tyler +8 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06996782·Phase 1, Phase 2·Recruiting·Listed May 2025

Apply to this trial

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for Solid Tumor

Drug: INBRX-106

Sites in Tyler +12 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 18+

Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019

Apply to this trial

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Drug: Rilvegostomig

Sites in Tyler, Houston +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06921785·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

for Ulcerative Colitis (UC)

Sites in Tyler, Garland +27 more locations

Sponsor: Xencor, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06619990·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Sites in Tyler, Mesquite +294 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

Sites in Tyler, Shenandoah +51 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting·Listed Aug 2024

Apply to this trial

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

Sites in Tyler, Dallas +111 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting·Listed Mar 2024

Apply to this trial

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

Sites in Tyler, Dallas +102 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05952557·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial

Product Surveillance Registry

for Cardiac Rhythm Disorders

Sites in Tyler, Dallas +127 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting·Listed Feb 2012

Apply to this trial

A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

Sites in Tyler, Plano +34 more locations

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06525220·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)

for Neoplasms

Sites in Tyler, Dallas +13 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06551142·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

Sites in Tyler, Dallas +83 more locations

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting·Listed Dec 2005

Apply to this trial

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

Sites in Tyler, Kingwood +28 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06679101·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial