Paid Clinical Trials in Virginia

Virginia has 1,910 paid clinical trials enrolling now across cities including Richmond, Charlottesville and Fairfax. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Virginia include University of Virginia Health, VCU Health and Inova Health, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,735 clinical trials

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Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Tremelimumab

Sites in Richmond +22 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03606967·Phase 2·Recruiting·Listed Jul 2018

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Charlottesville +32 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Norfolk +65 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

Drug: Cemiplimab

Sites in Richmond +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06980038·Phase 2·Recruiting·Listed May 2025

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A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

for Colon Cancer

Sites in Norfolk, Salem +12 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT07011576·Phase 2·Recruiting·Listed Jun 2025

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Genome Transplant Dynamics

for Thoracic Organ Transplantation

Sites in Falls Church +2 more locations

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 14 - 80

Code: NCT02423070·Recruiting·Listed Apr 2015

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

Sites in Richmond +30 more locations

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting·Listed Oct 2024

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International CRDS Registry

for Calcium Release Deficiency Syndrome

Sites in Fairfax +3 more locations

Sponsor: Population Health Research Institute

Sex: All·Age: All ages

Code: NCT06508164·Recruiting·Listed Jul 2024

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

Sites in Charlottesville +34 more locations

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting·Listed Aug 2020

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PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for Progressive Pulmonary Fibrosis

Sites in Charlottesville +6 more locations

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18 - 80

Code: NCT06855329·Recruiting·Listed Mar 2025

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Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

for Colorectal Cancer

2 locations in Richmond

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT06728072·Phase 2·Recruiting·Listed Dec 2024

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

Sites in Charlottesville +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting·Listed Nov 2020

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Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts

for Breast Cancer

Sites in Charlottesville +10 more locations

Sponsor: American College of Radiology

Sex: Female·Age: 45 - 74·Accepts healthy volunteers

Code: NCT05625659·Recruiting·Listed Nov 2022

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Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

Drug: Teclistamab

Sites in Richmond +13 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06465316·Phase 1·Recruiting·Listed Jun 2024

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in Bristol, Martinsville +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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Comparing the Attentional Demands and Functional Outcomes in People With Transradial Amputation

for Amputation

Sites in Richmond +1 more location

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT07075042·Recruiting·Listed Jul 2025

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

Sites in Charlottesville +32 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting·Listed Oct 2023

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RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

Sites in Reston +47 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting·Listed Dec 2020

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External Beam Radiation Therapy and Brachytherapy With Chemotherapy and Immunotherapy for the Treatment of Stage IVB Cervical Cancer

for Cervical Adenocarcinoma

Sites in Charlottesville +3 more locations

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06543576·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

Sites in Richmond, Charlottesville +11 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting·Listed Mar 2025

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Richmond +58 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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Early Screening and Treatment of Heart Complication in Sickle Cell Disease

for Sickle Cell Disease

Sites in Fairfax & Falls Church

Sponsor: Inova Health Care Services

Sex: All·Age: 18+

Code: NCT07023666·Phase 2·Recruiting·Listed Jun 2025

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Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes

for Lung Transplant

Sites in Falls Church +17 more locations

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06399302·Recruiting·Listed May 2024

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DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

Sites in Richmond +24 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting·Listed Oct 2023

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Charlottesville +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Richmond, Midlothian +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

for Myopia

Sites in Norfolk +16 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 5 - 11

Code: NCT07095894·Phase 3·Recruiting·Listed Jul 2025

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FearLess in NeuroOncology

for Primary Malignant Brain Tumor

1 location in Richmond

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT06989086·Recruiting·Listed May 2025

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Charlottesville +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting·Listed Jun 2025

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CRS Questionnaire Validation Project

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in Virginia City +4 more locations

Sponsor: The European Forum for Research and Education in Allergy and Airway Diseases

Sex: All·Age: 18+

Code: NCT06970977·Recruiting·Listed May 2025

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Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study

for Velopharyngeal Insufficiency

1 location in Charlottesville

Sponsor: Vanessa Torrecillas

Sex: All·Age: 18+

Code: NCT07264036·Recruiting·Listed Dec 2025

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mHealth Intervention for Pain Self Management

for Pain

1 location in Richmond

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18+

Code: NCT07332377·Recruiting·Listed Jan 2026

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Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery

for Neoadjuvant Treatment

Sites in Charlottesville +3 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06959511·Phase 2·Recruiting·Listed May 2025

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Richmond, Charlottesville +17 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

for Stroke

Sites in Charlottesville +27 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05907629·Recruiting·Listed Jun 2023

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The Impact of Chronic E-Cigarette Usage on Microvascular Health

for E-Cig Use

1 location in Richmond

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT06860698·Recruiting·Listed Mar 2025

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Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

for Obstructive Sleep Apnea

Sites in Norfolk +5 more locations

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT05508971·Recruiting·Listed Aug 2022

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A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Sites in Salem, Hampton +15 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04375033·Phase 4·Recruiting·Listed May 2020

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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

for Heart Failure

Drug: Finerenone

Sites in Richmond, Norfolk +80 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06008197·Phase 3·Recruiting·Listed Aug 2023

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Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)

for Angina Patients With Non-obstructive Coronary Artery Disease

1 location in Charlottesville

Sponsor: University of Virginia

Sex: Female·Age: 18+

Code: NCT06600178·Phase 1·Recruiting·Listed Sep 2024

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