Paid Clinical Trials in Walnut Creek, CA

As of August 2026, 179 paid clinical trials are recruiting in Walnut Creek, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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170 clinical trials

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Sites in Walnut Creek, Oakland +370 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting·Listed Dec 2022

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

Sites in Walnut Creek, Oakland +140 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting·Listed Jun 2022

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

Sites in Walnut Creek, Oakland +397 more locations

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting·Listed Jul 2023

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

Sites in Walnut Creek, Oakland +144 more locations

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting·Listed Feb 2016

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in Walnut Creek, Martinez +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

for Metastatic Nasopharyngeal Carcinoma

Drug: Relatlimab

Sites in Walnut Creek, Oakland +71 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06029270·Phase 2·Recruiting·Listed Sep 2023

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Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

for Colorectal Polyp

Sites in Walnut Creek, San Diego +14 more locations

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 65 - 82

Code: NCT05612347·Recruiting·Listed Nov 2022

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Walnut Creek, Mountain View +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Walnut Creek, Oakland +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

Sites in Walnut Creek, Berkeley +23 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting·Listed Oct 2023

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Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure

for Heart Failure With Reduced Ejection Fraction

Sites in Walnut Creek +4 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06526988·Recruiting·Listed Jul 2024

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Walnut Creek, Martinez +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Walnut Creek, Martinez +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial

for Glaucoma

Sites in Walnut Creek, San Francisco +5 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT05924477·Recruiting·Listed Jun 2023

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Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

for Non Small Cell Lung Cancer

Drug: Osimertinib

Sites in Walnut Creek, Emeryville +144 more locations

Sponsor: PrECOG, LLC.

Sex: All·Age: 18+

Code: NCT06538038·Recruiting·Listed Aug 2024

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Walnut Creek, Martinez +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment

for Prostate Cancer

Sites in Walnut Creek, Oakland +44 more locations

Sponsor: Canadian Cancer Trials Group

Sex: Male·Age: 18+

Code: NCT06235697·Phase 3·Recruiting·Listed Feb 2024

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Walnut Creek, Martinez +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

Sites in Walnut Creek, Oakland +292 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting·Listed Sep 2018

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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Walnut Creek, Vallejo +128 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

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Vancomycin Reduction Practices (VRP) in the NICU

for Antibiotic Stewardship

Sites in Walnut Creek, Oakland +11 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 18+

Code: NCT06772675·Recruiting·Listed Jan 2025

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Senicapoc in Alzheimer's Disease

for Mild Cognitive Impairment

Sites in Walnut Creek & Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 55 - 85·Accepts healthy volunteers

Code: NCT04804241·Phase 2·Recruiting·Listed Mar 2021

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Dementia and Diabetes Prevention Program

for Diabetes

1 location in Walnut Creek

Sponsor: University of California, Davis

Sex: All·Age: 60+

Code: NCT04141878·Recruiting·Listed Oct 2019

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Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

for Stage IV Esophageal Adenocarcinoma

Sites in Walnut Creek & San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT04221893·Recruiting·Listed Jan 2020

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Barotrauma in Hyperbaric Oxygen Therapy

for Barotrauma

1 location in Walnut Creek

Sponsor: John Muir Health

Sex: All·Age: 18+

Code: NCT05697328·Recruiting·Listed Jan 2023

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Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

for Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms

Drug: Solriamfetol

Sites in Walnut Creek, Sherman Oaks +38 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT07484217·Phase 3·Recruiting·Listed Mar 2026

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in Walnut Creek, Duarte +70 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

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A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Administered as Intramuscular Injection to Healthy Children 15 Months to 6 Years of Age

for Measles

Sites in Walnut Creek +16 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 15 Months - 6·Accepts healthy volunteers

Code: NCT07406360·Phase 3·Recruiting·Listed Feb 2026

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Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

for Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)

Sites in Walnut Creek, San Diego +2 more locations

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 18+

Code: NCT07266805·Phase 3·Recruiting·Listed Dec 2025

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Walnut Creek, Mountain View +325 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

for Binge-Eating Disorder

Drug: Solriamfetol

Sites in Walnut Creek, Encino +36 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 55

Code: NCT06413433·Phase 3·Recruiting·Listed May 2024

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Observational Study Protocol: LIVER-R

for Hepatobiliary Cancers

Sites in Walnut Creek, Los Angeles +22 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06252753·Recruiting·Listed Feb 2024

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Walnut Creek, San Francisco +61 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Walnut Creek, Santa Rosa +59 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting·Listed Oct 2024

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Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Walnut Creek, San Francisco +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 99

Code: NCT06467357·Phase 3·Recruiting·Listed Jun 2024

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An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

for Breast Cancer, Early Breast Cancer

Drug: Camizestrant

Sites in Walnut Creek, West Hollywood +102 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05952557·Phase 3·Recruiting·Listed Jul 2023

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A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

for HER2-positive Gastric Cancer

Drug: Rilvegostomig

Sites in Walnut Creek, Solvang +43 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06764875·Phase 3·Recruiting·Listed Jan 2025

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A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

for Chickenpox

Sites in Walnut Creek, Sacramento +48 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 Months - 15 Months·Accepts healthy volunteers

Code: NCT06740630·Phase 3·Recruiting·Listed Dec 2024

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Long-Term, Open-label Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE

for Hereditary Angioedema (HAE)

Sites in Walnut Creek, Santa Monica +10 more locations

Sponsor: Pharvaris Netherlands B.V.

Sex: All·Age: 12+

Code: NCT06679881·Phase 3·Recruiting·Listed Nov 2024

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Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Walnut Creek, Santa Monica +26 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06350097·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial