Paid Clinical Trials in Winston-Salem, NC

As of August 2026, 537 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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466 clinical trials

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

for Cannabis

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 25 - 59·Accepts healthy volunteers

Code: NCT04810858·Recruiting·Listed Mar 2021

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Winston-Salem, Clemmons +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Wake Forest Alzheimer's Disease Clinical Core

for Alzheimer's Disease

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT03140865·Recruiting·Listed May 2017

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Muscle Fiber Fragments for Improved Function of Rotator Cuff Musculature Following Rotator Cuff Repair

for Rotator Cuff

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 40 - 80

Code: NCT03752034·Recruiting·Listed Nov 2018

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Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

for Pancreas Adenocarcinoma

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05825066·Phase 2·Recruiting·Listed Apr 2023

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Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

Sites in Winston-Salem, Kernersville +42 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting·Listed Aug 2021

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Identifying Challenges to Healthy Aging in Persons With Human Immunodeficiency Virus (HIV) Age 50 and Older

for HIV

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 50+

Code: NCT05858034·Recruiting·Listed May 2023

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MRI in High-Grade Glioma Patients Undergoing Chemoradiation

for High Grade Glioma

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05212272·Recruiting·Listed Jan 2022

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Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

for Intra-Abdominal Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06876896·Recruiting·Listed Mar 2025

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Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit

for Depression

Sites in Winston-Salem & Greenville

Sponsor: East Carolina University

Sex: All·Age: 15 - 39

Code: NCT07173205·Recruiting·Listed Sep 2025

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Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

Sites in Winston-Salem +17 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting·Listed Feb 2025

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Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors

for Unspecified Adult Solid Tumor, Protocol Specific

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 120

Code: NCT00900471·Recruiting·Listed May 2009

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Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

for Nonsmall Cell Lung Cancer

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04253964·Phase 2·Recruiting·Listed Feb 2020

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Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

for Preoperative Care

Sites in Winston-Salem +4 more locations

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 45+

Code: NCT04973397·Recruiting·Listed Jul 2021

Apply to this trial

Post-Operative Cesarean Section Cosmesis

for Cesarean Delivery

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 44·Accepts healthy volunteers

Code: NCT06412978·Recruiting·Listed May 2024

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Improving Exercise Capacity With a Tailored Physical Activity Intervention

for Non Hodgkin Lymphoma

Sites in Winston-Salem +1 more location

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 85

Code: NCT05595577·Recruiting·Listed Oct 2022

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American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

Sites in Winston-Salem, Durham +28 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting·Listed Sep 2020

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Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures

for Depression in Old Age

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 65+

Code: NCT05851898·Phase 4·Recruiting·Listed May 2023

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A Pilot Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia

for Central Centrifugal Cicatricial Alopecia

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 75

Code: NCT04764331·Recruiting·Listed Feb 2021

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Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

for Food Insecurity

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06942598·Recruiting·Listed Apr 2025

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Evaluating the Effect of Surgical Drain Securement on Patient Quality of Life and Postoperative Drain-related Complications

for Surgical Drain

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06916286·Recruiting·Listed Apr 2025

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

Sites in Winston-Salem, Chapel Hill +66 more locations

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial

for Lipid Disorder

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 40 - 75

Code: NCT06488105·Phase 2·Recruiting·Listed Jul 2024

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Optimization of Postoperative Bowel Habits

for Constipation

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+

Code: NCT06335797·Recruiting·Listed Mar 2024

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Autologous Muscle Fiber Fragment Injections

for Fecal Incontinence

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05396456·Recruiting·Listed May 2022

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NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

for Overweight or Obesity

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 39·Accepts healthy volunteers

Code: NCT05674799·Recruiting·Listed Jan 2023

Apply to this trial

Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

Sites in Winston-Salem +16 more locations

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting·Listed Jan 2021

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Oral Gastric Suctioning Effect on Transesophageal Echo

for TEE Image Quality

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07209293·Recruiting·Listed Oct 2025

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A Mobile Intervention to Reduce Pain and Improve Health-III

for Chronic Pain

1 location in Winston-Salem

Sponsor: Wake Forest University

Sex: All·Age: 65+

Code: NCT06623669·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Take A Break - Rural

for Smoking

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05790486·Recruiting·Listed Mar 2023

Apply to this trial

The Myelin Disorders Biorepository Project

for Leukodystrophy

Sites in Winston-Salem +22 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting·Listed Feb 2017

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Winston-Salem, Chapel Hill +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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Bisphosphonate Use to Mitigate Bone Loss Secondary to Bariatric Surgery

for Bone Loss

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 30+

Code: NCT04922333·Phase 3·Recruiting·Listed Jun 2021

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Winston-Salem, Charlotte +39 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

Apply to this trial

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

for Non-small Cell Lung Cancer

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06567704·Recruiting·Listed Aug 2024

Apply to this trial

E-PRIME For Children With Medical Complexity

for Children With Medical Complexity

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: Up to 17

Code: NCT06216548·Recruiting·Listed Jan 2024

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A Longitudinal Study Looking at the Prevalence, Risk Factors & Consequences of Persistent Post-surgical Pain in Children

for Chronic Pain

Sites in Winston-Salem +6 more locations

Sponsor: Telethon Kids Institute

Sex: All·Age: Up to 16·Accepts healthy volunteers

Code: NCT06354699·Recruiting·Listed Apr 2024

Apply to this trial

Biomarker Development for Muscular Dystrophies

for Myotonic Dystrophy

Sites in Winston-Salem +3 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 5+·Accepts healthy volunteers

Code: NCT05019625·Recruiting·Listed Aug 2021

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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

for Hodgkin Lymphoma in Remission

Sites in Winston-Salem, Asheville +54 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT01790152·Recruiting·Listed Feb 2013

Apply to this trial

Efficacy of 3D-Printed Mouth Splints

for Microstomia

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 2 - 99

Code: NCT06801535·Recruiting·Listed Jan 2025

Apply to this trial