Paid Clinical Trials in North Carolina

North Carolina has 2,812 paid clinical trials enrolling now across cities including Durham, Chapel Hill and Winston-Salem. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in North Carolina include Duke University Medical Center, UNC Health and Wake Forest Baptist, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Obesity, Heart Failure, Multiple Myeloma — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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Newly added in North Carolina

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

2,435 clinical trials

Common conditions studied in North Carolina

  • Breast Cancer (60 active studies)
  • Obesity (45 active studies)
  • Cancer (42 active studies)
  • Heart Failure (36 active studies)
  • Multiple Myeloma (33 active studies)
  • Endometrial Cancer (26 active studies)

Leading research sponsors in North Carolina

  • Duke University
  • Wake Forest University Health Sciences
  • University of North Carolina, Chapel Hill
  • UNC Lineberger Comprehensive Cancer Center
  • National Cancer Institute (NCI)

Frequently asked questions

How many paid clinical trials are currently recruiting in North Carolina?

There are approximately 2,812 recruiting clinical trials in North Carolina listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in North Carolina pay participants?

Most recruiting trials in North Carolina compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in North Carolina?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in North Carolina?

The most common conditions under active study in North Carolina include Breast Cancer (60), Obesity (45), Cancer (42), Heart Failure (36), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in North Carolina?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in North Carolina on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in North Carolina?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Browse more clinical trials

All cities in North Carolina

Durham, NC(1,031)Chapel Hill, NC(696)Winston-Salem, NC(542)Charlotte, NC(509)Raleigh, NC(183)Greenville, NC(150)Wilmington, NC(108)Greensboro, NC(106)Asheville, NC(86)Huntersville, NC(64)Cary, NC(60)Pinehurst, NC(54)Morehead City, NC(52)Monroe, NC(47)Fayetteville, NC(46)Jacksonville, NC(35)Gastonia, NC(34)Statesville, NC(33)Hendersonville, NC(31)Concord, NC(30)Goldsboro, NC(30)Salisbury, NC(30)Morrisville, NC(28)Shelby, NC(28)New Bern, NC(27)Clinton, NC(26)High Point, NC(26)Matthews, NC(25)Hickory, NC(22)Research Triangle Park, NC(20)Hillsborough, NC(18)Wake Forest, NC(18)Burlington, NC(17)Clemmons, NC(17)Asheboro, NC(16)Kernersville, NC(15)Reidsville, NC(15)Wilson, NC(15)Mount Airy, NC(14)Denver, NC(13)Mooresville, NC(13)Albemarle, NC(12)Kinston, NC(12)Forest City, NC(10)Lincolnton, NC(10)Rocky Mount, NC(10)Thomasville, NC(10)Kannapolis, NC(8)Leland, NC(8)Fort Bragg, NC(7)Carrboro, NC(6)Clyde, NC(6)Garner, NC(6)North Wilkesboro, NC(6)Weaverville, NC(6)Lenoir, NC(5)Smithfield, NC(5)Kings Mountain, NC(4)Wilkesboro, NC(4)Bermuda Run, NC(3)Fort Liberty, NC(3)Oxford, NC(3)Sanford, NC(3)Washington, NC(3)Apex, NC(2)Charleston, NC(2)Edenton, NC(2)Fuquay-Varina, NC(2)Henderson, NC(2)Lumberton, NC(2)Marine Corps Base Camp Lejeune, NC(2)Morganton, NC(2)Stateville, NC(2)Supply, NC(2)Ahoskie, NC(1)Belmont, NC(1)Beulaville, NC(1)Bolivia, NC(1)Boone, NC(1)Clayton, NC(1)Cullowhee, NC(1)Elizabeth City, NC(1)Houston, NC(1)Huntsville, NC(1)Kenansville, NC(1)Laurinburg, NC(1)Lexington, NC(1)Multiple Locations, NC(1)Murphy, NC(1)Nags Head, NC(1)New London, NC(1)Pembroke, NC(1)Richlands, NC(1)Roanoke Rapids, NC(1)Rose Hill, NC(1)Roxboro, NC(1)Rutherfordton, NC(1)Salem, NC(1)Seymour-Johnson Air Force Base, NC(1)Southern Pines, NC(1)Waynesville, NC(1)Winstom Salem, NC(1)

Related healthcare resources in North Carolina

Trials by condition in North Carolina