Paid Clinical Trials in Winston-Salem, NC

As of August 2026, 537 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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Healthy volunteers only

466 clinical trials

A Study to Compare TAK-881 and HYQVIA in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Sites in Winston-Salem, Chapel Hill +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06747351·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial

Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)

for EPP

Sites in Winston-Salem +14 more locations

Sponsor: Tanabe Pharma America, Inc.

Sex: All·Age: 12 - 75

Code: NCT05005975·Phase 3·Recruiting·Listed Aug 2021

Apply to this trial

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

for Lumbar Disc Disease

Sites in Winston-Salem +13 more locations

Sponsor: BioRestorative Therapies

Sex: All·Age: 18+

Code: NCT04042844·Phase 2·Recruiting·Listed Aug 2019

Apply to this trial

Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

Sites in Winston-Salem, Chapel Hill +13 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS

for Interstitial Cystitis

Sites in Winston-Salem +10 more locations

Sponsor: Vaneltix Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05737121·Phase 2·Recruiting·Listed Feb 2023

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Clinical Study of a Vaginal Cooling Device for the Treatment of Vulvovaginal Candidiasis (VVC)

for Vulvovaginal Candidiasis (VVC)

Sites in Winston-Salem, Raleigh +6 more locations

Sponsor: Coologics, Inc

Sex: Female·Age: 22 - 49

Code: NCT06983041·Recruiting·Listed May 2025

Apply to this trial

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Winston-Salem +11 more locations

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 40+

Code: NCT05975983·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

for NHL

Sites in Winston-Salem +8 more locations

Sponsor: Indapta Therapeutics, INC.

Sex: All·Age: 18+

Code: NCT06119685·Phase 1, Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for Multiple Myeloma

Sites in Winston-Salem, Charlotte +4 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07555938·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot Study

for Sepsis, Septic Shock

Sites in Winston-Salem +4 more locations

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT07425587·Recruiting·Listed Feb 2026

Apply to this trial

BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System

for Leadless Pacemaker

Sites in Winston-Salem +6 more locations

Sponsor: Biotronik, Inc.

Sex: All·Age: 18+

Code: NCT07118358·Recruiting·Listed Aug 2025

Apply to this trial

Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets

for Brain Tumor

Sites in Winston-Salem +8 more locations

Sponsor: InSightec

Sex: All·Age: 18 - 100

Code: NCT05317858·Phase 3·Recruiting·Listed Apr 2022

Apply to this trial

STimulation to Activate RespIration

for ARDS (Moderate or Severe)

Sites in Winston-Salem +5 more locations

Sponsor: Lungpacer Medical Inc.

Sex: All·Age: 18+

Code: NCT06832306·Recruiting·Listed Feb 2025

Apply to this trial

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

for Parkinson Disease

Sites in Winston-Salem +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: All ages

Code: NCT03664609·Recruiting·Listed Sep 2018

Apply to this trial

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for Multiple Myeloma

Sites in Winston-Salem, Chapel Hill +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06892522·Phase 1, Phase 2·Recruiting·Listed Mar 2025

Apply to this trial

REMASTer: REcurrent Brain Metastases After SRS Trial

for Brain Metastases

Sites in Winston-Salem +7 more locations

Sponsor: Monteris Medical

Sex: All·Age: 18+

Code: NCT05124912·Recruiting·Listed Nov 2021

Apply to this trial

A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

for Myotonic Dystrophy Type 1 (DM1)

Sites in Winston-Salem +7 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 64

Code: NCT06185764·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Sites in Winston-Salem +3 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06704269·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

FiberLocker® System Augmentation of Rotator Cuff Repairs

for Rotator Cuff Tear

Sites in Winston-Salem +3 more locations

Sponsor: ZuriMED Technologies Inc.

Sex: All·Age: 30 - 70

Code: NCT06918041·Recruiting·Listed Apr 2025

Apply to this trial

Use of CereGate Therapy for Freezing of Gait in PD

for Parkinson Disease

Sites in Winston-Salem +6 more locations

Sponsor: CereGate Inc.

Sex: All·Age: 21 - 80

Code: NCT05292794·Recruiting·Listed Mar 2022

Apply to this trial

NIBP Validation Study

for Critical Illness

Sites in Winston-Salem +2 more locations

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: All ages

Code: NCT05673408·Recruiting·Listed Jan 2023

Apply to this trial

A Study Assessing KB407 for the Treatment of Cystic Fibrosis

for Cystic Fibrosis

Sites in Winston-Salem +5 more locations

Sponsor: Krystal Biotech, Inc.

Sex: All·Age: 18+

Code: NCT05504837·Phase 1·Recruiting·Listed Aug 2022

Apply to this trial

Phase 3 Study on the Efficacy and Safety of Human Plasma Derived Antithrombin (Atenativ) in Heparin-Resistant Patients Scheduled to Undergo Cardiac Surgery Necessitating Cardiopulmonary Bypass

for Acquired Antithrombin Deficiency

Sites in Winston-Salem, Durham +7 more locations

Sponsor: Octapharma

Sex: All·Age: 18 - 85

Code: NCT06096116·Phase 3·Recruiting·Listed Oct 2023

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A Multi-center, Early Feasibility Study of Using the Mechanical Tissue Resuscitation™ (MTR®) Therapy System for Removal of Excess Fluid in Subjects Who Have Had a Portion of Their Skull Removed to Expose the Dura/Brain and Require Drainage for Fluid Removal.

for Clinical Need for Craniotomy or Craniectomy

Sites in Winston-Salem +2 more locations

Sponsor: Renovo Concepts, Inc.

Sex: All·Age: 22 - 65

Code: NCT06201429·Recruiting·Listed Jan 2024

Apply to this trial

Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

for Overactive Bladder

Sites in Winston-Salem +8 more locations

Sponsor: InMode MD Ltd.

Sex: Female·Age: 22 - 80

Code: NCT07209397·Recruiting·Listed Oct 2025

Apply to this trial

Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

Sites in Winston-Salem +4 more locations

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting·Listed Oct 2024

Apply to this trial

Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS

for Acute Myeloid Leukemia, in Relapse

Sites in Winston-Salem, Charlotte +1 more location

Sponsor: ARCE Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06680752·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Safety and Effectiveness of the Yaari Extractor for Management of Shoulder Dystocia

for Shoulder Dystocia

Sites in Winston-Salem +3 more locations

Sponsor: FetalEase Ltd.

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05913609·Recruiting·Listed Jun 2023

Apply to this trial

A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Sites in Winston-Salem +8 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06538064·Recruiting·Listed Aug 2024

Apply to this trial

Prospective Clinical Evaluation of the BioFire Emerging Coronavirus Panel for the Detection of COVID-19 and Other Coronaviruses

for Coronavirus

Sites in Winston-Salem +5 more locations

Sponsor: BioFire Defense LLC

Sex: All·Age: All ages

Code: NCT07221097·Recruiting·Listed Oct 2025

Apply to this trial

The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial

for Non-cardiac Surgical

Sites in Winston-Salem, Durham +1 more location

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT06895590·Recruiting·Listed Mar 2025

Apply to this trial

A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)

for Septic Shock

Sites in Winston-Salem +4 more locations

Sponsor: Vivacelle Bio

Sex: All·Age: 18+

Code: NCT06072430·Phase 3·Recruiting·Listed Oct 2023

Apply to this trial

Treatment of Radiation and Cisplatin Induced Toxicities with Tempol

for Mucositis

Sites in Winston-Salem +7 more locations

Sponsor: Matrix Biomed, Inc.

Sex: All·Age: 18+

Code: NCT03480971·Phase 2·Recruiting·Listed Mar 2018

Apply to this trial

Home Sleep Therapy for Older Adults With MCI

for Mild Cognitive Impairment

Sites in Winston-Salem +1 more location

Sponsor: Brain Electrophysiology Laboratory Company

Sex: All·Age: 40 - 85·Accepts healthy volunteers

Code: NCT05771844·Recruiting·Listed Mar 2023

Apply to this trial

DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia

for Leukemia, Myeloid, Acute

Drug: Venetoclax

Sites in Winston-Salem +3 more locations

Sponsor: Delta-Fly Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06382168·Phase 1, Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

RIsE Stroke Mobility Study

for Acute Ischemic Stroke

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07638462·Recruiting·Listed Jun 2026

Apply to this trial

Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax

for IDH1 Mutation

Drug: Venetoclax

1 location in Winston-Salem

Sponsor: Timothy Pardee

Sex: All·Age: 18+

Code: NCT07471841·Phase 2·Recruiting·Listed Mar 2026

Apply to this trial

Personalized Exercise Program for Survivors of Breast Cancer, STEPS-BC Trial

for Anatomic Stage I Breast Cancer AJCC v8

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 85

Code: NCT07474090·Recruiting·Listed Mar 2026

Apply to this trial

BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

for Heart Failure With Preserved Ejection Fraction

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55+

Code: NCT07413198·Recruiting·Listed Feb 2026

Apply to this trial

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

for Sarcoma Metastatic

Sites in Winston-Salem & Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07291297·Phase 2·Recruiting·Listed Dec 2025

Apply to this trial