Paid Clinical Trials in Worcester, MA

As of August 2026, 204 paid clinical trials are recruiting in Worcester, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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Healthy volunteers only

174 clinical trials

The Periviable GOALS Decision Support Tool

for Pregnancy Preterm

Sites in Worcester +11 more locations

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05264779·Recruiting·Listed Mar 2022

Apply to this trial

Supporting Treatment Access and Recovery in COD

for Opioid Use Disorder

Sites in Worcester, Orange +3 more locations

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT05138614·Recruiting·Listed Dec 2021

Apply to this trial

Social Needs Screening and Chronic Diseases Study (WE CARE)

for Hyperlipidemias

3 locations in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06903897·Recruiting·Listed Apr 2025

Apply to this trial

Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

Sites in Worcester, Boston +17 more locations

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting·Listed Jul 2023

Apply to this trial

Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application

for Epilepsy

Sites in Worcester +1 more location

Sponsor: Dartmouth-Hitchcock Medical Center

Sex: All·Age: 18+

Code: NCT06425029·Recruiting·Listed May 2024

Apply to this trial

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

Sites in Worcester, Boston +34 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting·Listed May 2022

Apply to this trial

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Worcester, Burlington +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial

The Role of Occupational Therapy for Improving Medication Management for Persons With AMD, DR and Glaucoma

for Age-Related Macular Degeneration

1 location in Worcester

Sponsor: MCPHS University

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06593405·EARLY_Phase 1·Recruiting·Listed Sep 2024

Apply to this trial

Testimonials and Navigation in Rheumatology

for Rheumatologic Disease

Sites in Worcester, Boston +1 more location

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT06469788·Recruiting·Listed Jun 2024

Apply to this trial

Asthma Link Effectiveness Trial

for Childhood Asthma

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 5 - 14

Code: NCT06388460·Recruiting·Listed Apr 2024

Apply to this trial

Real-Time Cholangioscopy Artificial Intelligence Evaluation of Biliary Strictures

for Biliary Stricture

Sites in Worcester +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05779436·Recruiting·Listed Mar 2023

Apply to this trial

ShotBlocker During Intramuscular Injection Randomized Control Trial

for Neonatal Pain

1 location in Worcester

Sponsor: Lauren Fortier

Sex: All·Age: 37 Weeks - 42 Weeks·Accepts healthy volunteers

Code: NCT06624176·Recruiting·Listed Oct 2024

Apply to this trial

Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

for Internuclear Ophthalmoplegia

Sites in Worcester +1 more location

Sponsor: Kevin Houston

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06417216·Recruiting·Listed May 2024

Apply to this trial

Fecal Microbiota Transplant National Registry

for Fecal Microbiota Transplantation

Sites in Worcester, Boston +26 more locations

Sponsor: American Gastroenterological Association

Sex: All·Age: All ages

Code: NCT03325855·Recruiting·Listed Oct 2017

Apply to this trial

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

for Fusion of Spine, Lumbar Region

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT06528288·Recruiting·Listed Jul 2024

Apply to this trial

Early Detection of Gestational Diabetes Mellitus in Pregnancy

for Gestational Diabetes Mellitus in Pregnancy

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT05388643·Recruiting·Listed May 2022

Apply to this trial

Promoting Early Intervention Timing and Attention to Language

for MONITOR

Sites in Worcester +1 more location

Sponsor: University of California, Los Angeles

Sex: All·Age: 6 Months - 8 Months

Code: NCT05853861·Recruiting·Listed May 2023

Apply to this trial

Cranberry and Gut Health in Crohn's Disease

for Crohn Disease (CD)

1 location in Worcester

Sponsor: Ana Maldonado-Contreras

Sex: All·Age: 18 - 65

Code: NCT07170462·EARLY_Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

Skilled Nursing Facility at Home Trial

for Skilled Nursing Facility

Sites in Worcester & Springfield

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT06547645·Recruiting·Listed Aug 2024

Apply to this trial

Enhanced Coordinated Specialty Care for Early Psychosis

for Psychosis

Sites in Worcester, Belmont +3 more locations

Sponsor: Mclean Hospital

Sex: All·Age: All ages

Code: NCT06071858·Recruiting·Listed Oct 2023

Apply to this trial

Retropubic Hydrodissection and Trocar-induced Bladder Perforation During Retropubic Midurethral Slings

for Bladder Perforation

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07208682·Recruiting·Listed Oct 2025

Apply to this trial

Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A

for Suicidal Ideation

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT06223867·Recruiting·Listed Jan 2024

Apply to this trial

Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile

for Clostridium Difficile Infection Recurrence

1 location in Worcester

Sponsor: Krunal Patel

Sex: All·Age: 16+

Code: NCT03562741·Recruiting·Listed Jun 2018

Apply to this trial

Mirai-MRI: Validation of AI Models for Breast Cancer Risk

for Cancer Risk

Sites in Worcester +3 more locations

Sponsor: University of California, San Francisco

Sex: Female·Age: 40 - 89·Accepts healthy volunteers

Code: NCT07121972·Recruiting·Listed Aug 2025

Apply to this trial

Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)

for Relapsing Multiple Sclerosis

Sites in Worcester +19 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT04047628·Phase 3·Recruiting·Listed Aug 2019

Apply to this trial

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

for Cystic Fibrosis

Sites in Worcester, Boston +66 more locations

Sponsor: Nicole Hamblett

Sex: All·Age: 12+

Code: NCT06504589·Recruiting·Listed Jul 2024

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Promoting Improved Functioning Among People Experiencing Stressful Situations

for Acute Stress Reaction

Sites in Worcester +3 more locations

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 50

Code: NCT06482567·Recruiting·Listed Jul 2024

Apply to this trial

Effect of Support for Low-Income Mothers of Preterm Infants

for Preterm Birth

Sites in Worcester, Springfield +2 more locations

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06362798·Recruiting·Listed Apr 2024

Apply to this trial

Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+

Code: NCT07072039·Recruiting·Listed Jul 2025

Apply to this trial

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients

for Psoriatic Arthritis

Drug: Guselkumab

Sites in Worcester +13 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18 - 80

Code: NCT05669833·Phase 3·Recruiting·Listed Jan 2023

Apply to this trial

Individualizing Treatment for Asthma in Primary Care (Full Study)

for Asthma

Sites in Worcester +12 more locations

Sponsor: DARTNet Institute

Sex: All·Age: 13 - 75

Code: NCT07052942·Phase 4·Recruiting·Listed Jul 2025

Apply to this trial

PRospective phenotypIng and Multi-omic Endotyping of Progressive Pulmonary Fibrosis

for Progressive Pulmonary Fibrosis

Sites in Worcester +4 more locations

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18 - 80

Code: NCT06855329·Recruiting·Listed Mar 2025

Apply to this trial

Ear-Seizure Detection (EarSD) Study

for Seizures

2 locations in Worcester

Sponsor: Felicia Chu

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06598189·Recruiting·Listed Sep 2024

Apply to this trial

Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices

for Complex Aortic Aneurysms

1 location in Worcester

Sponsor: Andres Schanzer

Sex: All·Age: 18+

Code: NCT02050113·Recruiting·Listed Jan 2014

Apply to this trial

Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

for May-Thurner Syndrome

1 location in Worcester

Sponsor: Ningcheng Peter Li

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06888024·Recruiting·Listed Mar 2025

Apply to this trial

Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension

for Postpartum Hypertension

Sites in Worcester +2 more locations

Sponsor: Yale University

Sex: Female·Age: 18+

Code: NCT05884190·Recruiting·Listed Jun 2023

Apply to this trial

Cytomegalovirus (CMV) Transmission and Immune Tracking (TransmIT) Study

for Cytomegalovirus Infections

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 1 Day - 36 Months

Code: NCT06522880·Recruiting·Listed Jul 2024

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in Worcester, Boston +49 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial

MIRAI-MRI: Comparing Screening MRI for Patients at High Risk for Breast Cancer Identified by Mirai and Tyrer-Cuzick

for Breast Cancer

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 40+

Code: NCT05968157·Recruiting·Listed Aug 2023

Apply to this trial

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

for Essential Thrombocythemia

Sites in Worcester, Boston +39 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07623200·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial