Milwaukee, WI Clinical Trials Report — June 2026

For Milwaukee residents considering participation in clinical research, June 2026 presents both urgent opportunities and new avenues for contributing to medical science. Across Milwaukee, WI, a total of 637 clinical trials are currently recruiting participants across 182 research facilities.

Prompt action is essential for those interested in trials nearing their enrollment deadlines. A total of 34 clinical trials are slated to conclude within the next 90 days. This urgency is particularly relevant for healthy volunteers, as 4 of these rapidly closing studies are still actively seeking participants without specific health conditions. These trials offer a chance to contribute to medical advancements before their enrollment windows close.

New Research Opportunities in Milwaukee

This month, Milwaukee saw the opening of 3 new clinical trials, a decrease from the 5 trials that launched in May 2026. These new studies bring fresh opportunities for participants to engage with cutting-edge treatments and diagnostic approaches across a range of health challenges.

Notable new trials include significant studies from major sponsors:

• Montefiore Medical Center is sponsoring NCT07631598, "Buprenorphine Implementation at Syringe Service Programs to Reduce Overdoses." This study aims to determine if offering buprenorphine treatment directly at syringe service programs (SSPs) helps more people start and stay in treatment for opioid use disorder (OUD) than referring them to community buprenorphine treatment providers. Buprenorphine is a medication used to treat OUD. This trial is seeking 512 participants.
• The Medical College of Wisconsin is leading NCT07643428, "Cancer Lipidome Adaptation and Resculping Through Omega-3 PUFAs in Breast Tumors." This single-arm Phase 2 interventional treatment study will investigate changes in tissue lipidomes with omega-3 polyunsaturated fatty acids (PUFA) supplementation and correlations with pathological response in patients with early-stage breast cancer. This study is seeking 35 participants.

The 3 new trials opened this month are exploring a range of conditions, including breast cancer, opioid use disorder (covering moderate and severe forms), and primary progressive aphasia. The Medical College of Wisconsin sponsored 2 of these new trials, with Montefiore Medical Center sponsoring the remaining 1.

Leading Research Facilities in Milwaukee

Milwaukee is home to several prominent research institutions that consistently run a high volume of clinical trials. These facilities are key destinations for individuals seeking to participate in medical research:

• Medical College of Wisconsin (229 trials)
• Aurora Sinai Medical Center (51 trials)
• Aurora Saint Luke's Medical Center (49 trials)
• Aurora Cancer Care-Milwaukee (47 trials)
• Children's Hospital of Wisconsin (45 trials)
• Research Site (23 trials)
• Froedtert Hospital & the Medical College of Wisconsin (18 trials)
• Children's Wisconsin (17 trials)
• Froedtert Hospital and the Medical College of Wisconsin (16 trials)
• Froedtert Hospital (16 trials)
• The Medical College of Wisconsin (12 trials)
• Froedtert & the Medical College of Wisconsin (12 trials)

The Medical College of Wisconsin stands out as the city's most active research site, hosting a significant portion of Milwaukee's clinical trials. Its extensive research portfolio makes it a central hub for medical innovation in the region.

Impending Deadlines for Key Health Areas

Patients managing specific health conditions also face impending deadlines to join research. Trials focused on various cancers and other conditions are among those with limited time remaining for enrollment. Conditions with trials closing soon include:

• Hematologic tests (2 trials)
• AML (2 trials)
• Advanced breast cancer (1 trial)
• Aging (1 trial)
• All, adult (1 trial)
• Deep venous thrombosis (1 trial)
• Athletic injuries (1 trial)
• AML with mutated NPM1 (1 trial)
• Breast cancer (1 trial)
• Burkitt lymphoma (1 trial)

Opportunities for Healthy Volunteers

For individuals without a specific medical condition, there are significant opportunities to contribute to research. Of the 3 new trials launched this month, 1 is actively seeking healthy volunteers. Across Milwaukee, a total of 49 clinical trials are currently recruiting healthy participants, providing numerous avenues for those interested in supporting medical research.

Broadening Your Search: Nearby Options

While Milwaukee offers a wide array of clinical trial opportunities, individuals may also find options in nearby communities within Wisconsin. Cities with active trials include Madison (10 trials), Eau Claire (2 trials), Kenosha (2 trials), Sheboygan (1 trial), and Wauwatosa (1 trial).

Participation in clinical trials is open to a diverse range of individuals. Of the 3 new trials launched this month, all 3 include older adults, ensuring that senior populations have ample opportunity to contribute to medical science. No new trials this month are exclusively for children, females, or males.

As we move through June, Milwaukee's robust research community will continue to drive medical innovation, offering diverse opportunities for individuals to contribute to the future of healthcare.