Paid Clinical Trials in Madison, WI
As of August 2026, 556 paid clinical trials are recruiting in Madison, Wisconsin. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Madison offers studies at sites including University of Wisconsin for conditions such as Prostate Cancer, Acute Myeloid Leukemia, Breast Cancer, Colorectal Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Madison
Trials by drug in Madison
Filter results
Newly added in Madison
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Evaluate the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
The ENHANCE Project Toolkit
482 clinical trials
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
A Study of ASP3082 in Adults With Advanced Solid Tumors
FOG-001 in Locally Advanced or Metastatic Solid Tumors
A First-in-Human Study of MEN2312 in Adults With Advanced Breast Cancer
A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Top Research Study Locations in Madison
Researchers run research studies in Madison, WI at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| University of Wisconsin | Cystic Fibrosis, Alzheimer Disease, Healthy | 113 |
| University of Wisconsin Carbone Cancer Center - University Hospital | Acute Myeloid Leukemia, Metastatic Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 89 |
| University of Wisconsin Carbone Cancer Center - Eastpark Medical Center | Metastatic Malignant Solid Neoplasm, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 58 |
| University of Wisconsin - Madison | Gastroschisis, Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL) | 38 |
| University of Wisconsin Carbone Cancer Center | Prostate Cancer, Acute Myeloid Leukemia, Breast Cancer | 29 |
| University of Wisconsin-Madison | Achondroplasia, Acute Respiratory Failure, Acute Sinusitis | 21 |
| William S. Middleton Memorial Veterans Hospital, Madison, WI | Metastatic Prostate Cancer, Aging, Alcohol Use Disorder | 14 |
| William S Middleton VA Medical Center | Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myelodysplastic Syndrome | 13 |
| UW School of Medicine and Public Health | Diabetic Retinopathy, Aphasia, Diabetes Mellitus | 12 |
| UW Carbone Cancer Center | Breast Cancer, Metastatic Cancer, Advanced Breast Cancer | 8 |
| University of Wisconsin Hospital and Clinics | Pulmonary Hypertension, AML With Mutated NPM1, Acute Myeloid Leukemia | 8 |
| UW Hospital and Clinics | Cytomegalovirus Infections, Diabetic Retinopathy, High-need, High-complexity | 7 |
| American Family Children's Hospital | Cardiac Arrest, Out-Of-Hospital, Hospitalized Child, Hypothermia, Induced | 6 |
| University of Wisconsin Madison | Asthma, Alzheimer's Disease, Asthma Chronic | 6 |
| University of Wisconsin School of Medicine and Public Health | Breast Cancer, Genetic Disease, HER2-negative Breast Cancer | 5 |
| UW Health | ACL, Communication, G12D Mutated KRAS | 4 |
| UW Health University Hospital | Consciousness Disorders, Fracture Fixation, Idiopathic Pulmonary Fibrosis | 4 |
| University Hospital and UW Health Clinics | Interstitial Lung Disease, Progressive Pulmonary Fibrosis, Achondroplasia | 4 |
| University of Wisconsin - Carbone Cancer Center | Breast Neoplasms, Cholangiocarcinoma, Colorectal Cancer | 4 |
| University of Wisconsin Clinical Science Center | Cervical Cancer, Leukemia, Leukemia, Myeloid | 4 |
| University of Wisconsin Madison - Waisman Center Bone Dysplasia Clinic | Hypochondroplasia, Achondroplasia | 4 |
| University of Wisconsin, Madison | Atrial Arrhythmia, Atrial Tachycardia, CLOVES Syndrome | 4 |
| Center for Healthy Minds | Asthma, Depression, Anxiety, Well-Being, Psychological | 3 |
| Meriter Hospital | Aging, Alzheimer Disease, Caregiver Burden | 3 |
| University Hospital | Acute Treatment of Migraine, Opiate Use Disorder, Opiate-Related Disorders | 3 |
Active & Upcoming Studies in Madison (2026)
Recruiting trials in Madison grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (198 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma · Phase 3 · AbbVie
Cardiovascular (27 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA) · VA Office of Research and Development
Neurology & pain (24 active studies)
- The Gut - PRO Study · Phase 2 · University of Wisconsin, Madison
- Lily's Grace Temporal Interference · University of Wisconsin, Madison
Mental health & behavior (18 active studies)
- The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study · University of Wisconsin, Madison
- Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls · University of Wisconsin, Madison
Pediatric (13 active studies)
- Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children · University of Wisconsin, Madison
- Testing and Evaluating an Interactive Media Use Journal for Adolescents · University of Wisconsin, Madison
Diabetes & metabolic (10 active studies)
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome · EARLY_Phase 1 · University of Wisconsin, Madison
- Leveraging Artificial Intelligence to Prevent Vision Loss From Diabetes · University of Wisconsin, Madison
Eye & vision (3 active studies)
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
- Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID) · University of Wisconsin, Madison
Vaccines (1 active study)
Common conditions studied in Madison
- Prostate Cancer (12 active studies)
- Acute Myeloid Leukemia (11 active studies)
- Breast Cancer (11 active studies)
- Colorectal Cancer (7 active studies)
- Achondroplasia (6 active studies)
- Advanced Solid Tumor (6 active studies)
Leading research sponsors in Madison
- University of Wisconsin, Madison
- National Cancer Institute (NCI)
- Children's Oncology Group
- VA Office of Research and Development
- Merck Sharp & Dohme LLC
Frequently asked questions
How many paid clinical trials are currently recruiting in Madison?
There are approximately 556 recruiting clinical trials in Madison, Wisconsin listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Madison pay participants?
Most recruiting trials in Madison compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Madison?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Madison?
The most common conditions under active study in Madison include Prostate Cancer (12), Acute Myeloid Leukemia (11), Breast Cancer (11), Colorectal Cancer (7), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Madison?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Madison on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Madison?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Madison?
Recruiting research sites in Madison include University of Wisconsin, University of Wisconsin Carbone Cancer Center - University Hospital, University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Madison right now?
The largest active categories in Madison are Cancer & tumors (198), Cardiovascular (27), Neurology & pain (24). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.