Erlotinib, Docetaxel, and Carboplatin in Treating Patients With Newly Diagnosed Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Part of paid clinical trials in Seattle, Washington.
- Sponsor
- Fred Hutchinson Cancer Center
- Study ID
- NCT00217529
- Phase
- PHASE1/PHASE2
- Status
- Completed
Conditions
- Fallopian Tube Cancer
- Ovarian Cancer
- Peritoneal Cavity Cancer
Eligibility Criteria
- Sex
- FEMALE
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- pegfilgrastim — BIOLOGICAL
- carboplatin — DRUG
- docetaxel — DRUG
- erlotinib hydrochloride — DRUG
Study Details
RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as docetaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving erlotinib together with docetaxel and carboplatin may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of erlotinib when given together with docetaxel and carboplatin and to see how well they work in treating patients with newly diagnosed stage III or stage IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer.
Key Dates
- First listed
- Sep 22, 2005
- Start date
- Jun 30, 2004
- Status verified
- Sep 2010
- Primary completion
- Nov 30, 2005
Study Design
- Primary purpose
- TREATMENT
Primary Outcome Measure
Maximum tolerated dose of erlotinib
Locations (3)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109-1024 | - |
| Pacific Gynecology Specialists | Seattle | Washington | 98104 | - |
| University of Washington School of Medicine | Seattle | Washington | 98195 | - |
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