Ovarian cancer Clinical Trials

Recruiting ovarian cancer studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat ovarian cancer. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting ovarian cancer studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting ovarian cancer trials

Within

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

11 sites incl. Arcadia

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT07741968

Apply to this trial

Study of Autologous, Metabolically Optimized, CD137+ Tumor-Infiltrating Lymphocytes Followed by Consolidative Oral Cyclophosphamide, Bevacizumab, and Pembrolizumab

for Ovarian Cancer

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: Female·Age: 18 - 80

Code: NCT07720180·Phase 2

A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation

for Ovarian Cancer

Sponsor: LG Chem

Sex: All·Age: 18+

Code: NCT07752875·Phase 1, Phase 2

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

for Pancreas Cancer

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07732686

An International Field Study of the Reliability and Validity of a Disease-Specific Questionnaire Module (the QLQ-OV28) in Assessing the Quality of Life of Patients With Ovarian Cancer - Phase III

for Ovarian Cancer

Sponsor: Helios University Hospital Wuppertal

Sex: Female·Age: 18+

Code: NCT07465133

Study of CryptiVax-1001 in Maintenance Setting for Advanced Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

for Ovarian Cancer

Sponsor: Epitopea Ltd

Sex: Female·Age: 18+

Code: NCT07665515·Phase 1

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Trastuzumab Rezetecan and Carboplatin ± Bevacizumab Versus Investigator's Choice Chemotherapy in Patients With Platinum-sensitive Recurrent Ovarian Cancer

for Ovarian Cancer

Sponsor: Sun Yat-sen University

Sex: Female·Age: 18 - 75

Code: NCT07776171·Phase 2

A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)

for Ovarian Cancer

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07776691·Phase 3

A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors.

for Ovarian Cancer

Sponsor: Phrontline Biopharma

Sex: All·Age: 18+

Code: NCT07778498·Phase 1, Phase 2

Efficacy and Safety of Sacituzumab in Patients With OCCC After Immunotherapy Progression

for Ovarian Cancer

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sex: Female·Age: 18 - 70

Code: NCT07168083

IGFBP-2 Vaccine to Prevent Ovarian Cancer Progression in Patients With Serologic Detection of Recurrence

for Fallopian Tube Carcinoma

1 site in Seattle

Sponsor: University of Washington

Sex: Female·Age: 18+

Code: NCT07495124·Phase 2

Apply to this trial

Predictors of Cognitive Decline and Delirium in Older Women With Ovarian Cancer

for Ovarian Cancer

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: Female·Age: 70+

Code: NCT07716800

Clinical Trials Comparing Trastuzumab Plus Bevacizumab With Bevacizumab as First-line Maintenance Therapy for Epithelial Ovarian Cancer

for Ovarian Cancer

Sponsor: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Sex: Female·Age: 18+

Code: NCT07779538·Phase 3

Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer

for Bladder Cancer

3 sites incl. Boston

Sponsor: Lumina Pharmaceuticals Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07781852·EARLY_Phase 1

89Zr-DFO-Mirvetuximab PET/CT Imaging for Companion Diagnosis and Response Evaluation in Ovarian Cancer

for Epithelial Ovarian Cancer

Sponsor: Peking University Cancer Hospital & Institute

Sex: Female·Age: 18+

Code: NCT07790939·EARLY_Phase 1

PITCH - Impacting Hereditary Cancer Testing

for Ovarian Cancer

1 site in Lexington

Sponsor: Rachel Miller

Sex: Female·Age: 18+

Code: NCT07090109

Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian Cancer

for Platinum-Sensitive Ovarian Cancer

2 sites incl. Danbury

Sponsor: Genmab

Sex: Female·Age: 18+

Code: NCT07564141·Phase 3

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Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer

for Ovarian Cancer

1 site in Pittsburgh

Sponsor: Kalinski, Pawel, MD, PhD

Sex: Female·Age: 18+

Code: NCT07634094·Phase 2

Safety and Efficacy of Ubamatamab With First-line Chemotherapy in Ovarian Cancer

for Ovarian Cancer

Sponsor: ARCAGY/ GINECO GROUP

Sex: Female·Age: 18+

Code: NCT07637851·Phase 1, Phase 2

CYTALUX Dose Extension Study

for Cancer in the Lung

Sponsor: On Target Laboratories, LLC

Sex: All·Age: 18+

Code: NCT07469202·Phase 4

A Clinical Study of SYS6041 Combination Therapy for Recurrent Ovarian Cancer

for Ovarian Cancer

Sponsor: CSPC Megalith Biopharmaceutical Co.,Ltd.

Sex: All·Age: 18+

Code: NCT07714668·Phase 2

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Continued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC)

for Low Grade Ovarian Serous Adenocarcinoma

Sponsor: Verastem, Inc.

Sex: Female·Age: 18+

Code: NCT07747506·Phase 2

Implementation of New Models of Ovarian Carcinoma Resistant to Therapy

for Ovarian Cancer

Sponsor: Mario Negri Institute for Pharmacological Research

Sex: Female·Age: 18+

Code: NCT07757711

Opportunistic Salpingectomy During Bariatric Surgery for Ovarian Cancer Prevention

for Ovarian Cancer

Sponsor: St. Joseph's Healthcare Hamilton

Sex: Female·Age: All ages

Code: NCT07761416·EARLY_Phase 1

A Single-Arm, Open-Label, Prospective Study Evaluating the Safety, Tolerability, and Immunogenicity of the NeoOVIV Vaccine in Patients With Ovarian Cancer After Surgery

for Ovarian Cancer

Sponsor: West China Hospital

Sex: Female·Age: 18 - 75

Code: NCT07676890·Phase 1

DISARM Clinical Study B: Evaluation of Innovative Ovarian Cancer Biomarker Assays

for Ovarian Cancer

Sponsor: National and Kapodistrian University of Athens

Sex: Female·Age: 35+·Accepts healthy volunteers

Code: NCT07693894

A Single-Arm, Open-Label, Prospective Study Evaluating the Safety, Tolerability, and Immunogenicity of the NeoOVSV Vaccine in Patients With Ovarian Cancer After Surgery

for Ovarian Cancer

Sponsor: West China Hospital

Sex: Female·Age: 18 - 75

Code: NCT07724106·Phase 1

Study Evaluating Safety, Tolerability, and Metabolism of Niraparib

for Ovarian Cancer

3 sites incl. Fort Lauderdale

Sponsor: University of Miami

Sex: Female·Age: 18+

Code: NCT06412120·Phase 4

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68Ga-SorB PET/CT Imaging in Patients With Solid Tumors

for Melanoma (Skin Cancer)

Sponsor: Peking University Third Hospital

Sex: All·Age: 18 - 75

Code: NCT07760012

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Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.

for Ovarian Cancer

2 sites incl. Irving

Sponsor: ArriVent BioPharma, Inc.

Sex: Female·Age: 18+

Code: NCT07755436·Phase 1

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A Real-world Study of Mirvetuximab Soravtansine (MIRV) in Ovarian Cancer Patients of Expression of Folate Receptor α（FRα）

for Ovarian Cancer

Sponsor: NING LI-GYN

Sex: Female·Age: 18+

Code: NCT07690332

A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)

for Ovarian Cancer

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07743164·Phase 3

Evaluation of XYA02 in Patients With Advanced Solid Tumors

for MUC1-expressing Advanced, Relapsed and/or Refractory Solid Tumors

Sponsor: XYone Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT07670312·Phase 1, Phase 2

SL-28 for Advanced Solid Tumours

for Head & Neck Cancer

Sponsor: Second Life Therapeutics

Sex: All·Age: 18+

Code: NCT07341737·Phase 1, Phase 2

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Study to Assess Prevalence of the Folate Receptor Alpha (FRa) in Adult Female Participants With Ovarian Cancer in Intercontinental (InterCon) Countries

for Ovarian Cancer

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07539844

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Application of Cardiophrenic Lymphadenectomy in Advanced Ovarian Cancer: A Single-Center Prospective Exploratory Study

for Ovarian Cancer

Sponsor: manxiaxia

Sex: Female·Age: 18 - 70

Code: NCT07572409

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Prospective Sample Collection Study for a Blood-Based cfDNA Methylation Assay for Ovarian Cancer Detection

for Ovarian Neoplasms

Sponsor: Tongji Hospital

Sex: Female·Age: All ages

Code: NCT07593833

Blood-Based Minimal Residual Disease in Advanced Epithelial Ovarian Cancer After 1st Line Therapy

for Ovarian Neoplasms

Sponsor: Asan Medical Center

Sex: Female·Age: 19+

Code: NCT07670962

Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors

for Breast Cancer

5 sites incl. Los Angeles

Sponsor: Regor Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07524322·Phase 1

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Study of CKD-215 and D215 in Adults With BRCA-mutated Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

for Ovarian Cancer

Sponsor: Chong Kun Dang Pharmaceutical

Sex: Female·Age: 19 - 75

Code: NCT07532148·Phase 1

Phase 1, Safety and Tolerability Study of XmAb541 and XmAb808 in Advanced Solid Tumors

for Ovarian Cancer

4 sites incl. Lake Success

Sponsor: Xencor, Inc.

Sex: Female·Age: 18+

Code: NCT07593092·Phase 1

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68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors

for Prostate Cancer

Sponsor: Peking University Cancer Hospital & Institute

Sex: All·Age: 18 - 75

Code: NCT07639801

Fluzoparib + Bevacizumab vs Olaparib + Bevacizumab for Maintenance Therapy in HRD-Positive Advanced Ovarian Cancer

for Ovarian Cancer

Sponsor: Shandong University

Sex: Female·Age: 18+

Code: NCT07647653·Phase 2

NK521 in the Treatment of Advanced Solid Tumors

for Hepatocellular Carcinoma (HCC)

Sponsor: Base Therapeutics (Shanghai) Co., Ltd.

Sex: All·Age: 18 - 65

Code: NCT07657416·EARLY_Phase 1

A Phase 1 Study to Evaluate the Safety and Efficacy of OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.

for Endometrial Cancer Recurrent

Sponsor: Outpace Bio, Inc.

Sex: Female·Age: 18+

Code: NCT07664735·Phase 1

A Study Evaluating the Immunotherapy Treatment for Ovarian Cancer and Other Advanced Malignancies.

for Ovarian Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07389239·Phase 1, Phase 2

Normethermic Intraperitoneal Chemotherapy - a Novel Concept for Local Treatment of the Elderly and Fragile Women With Advanced Ovarian Cancer?

for Ovarian Cancer

Sponsor: Odense University Hospital

Sex: Female·Age: 70+

Code: NCT07733505·Phase 1

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Prehabilitation in High-risk Oncologic Surgery

for Pancreatic Cancer

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07638410

Iparomlimab and Tuvonralimab Plus Chemotherapy as Neoadjuvant Therapy for Ovarian Cancer（Phase II）

for Ovarian Cancer

Sponsor: Obstetrics & Gynecology Hospital of Fudan University

Sex: Female·Age: 18 - 75

Code: NCT07673835·Phase 2

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations

for Advance Solid Tumors

Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

Sex: All·Age: 18+

Code: NCT07610798·Phase 1, Phase 2

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Combined Program of Supervised Physical Exercise and Nutritional Counseling in Ovarian Cancer Patients on Frontline Maintenance Treatment With PARP Inhibitors

for Ovarian Cancer

Sponsor: Oncare Madrid

Sex: Female·Age: 18+

Code: NCT06139783

Enumeration and Functional Analysis of Circulating Tumor Cells for Homologous Recombination: a Prospective Single-center Study on Advanced/Metastatic Solid Tumors

for Breast Cancer

Sponsor: Centre Leon Berard

Sex: All·Age: 18+

Code: NCT07555600

A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies

for Ovarian Cancer

Sponsor: Zelluna Immunotherapy AS

Sex: All·Age: 18 - 75

Code: NCT07613723·Phase 1

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Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

for Ovarian Cancer

1 site in Orange

Sponsor: University of California, Irvine

Sex: Female·Age: 18+

Code: NCT04520139·Phase 1, Phase 2

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Evaluating the Feasibility of Prehabilitation Delivery Models for Patients Preparing for Ovarian Cancer Surgery

for Prehabilitation

Sponsor: Jordan Leitch

Sex: Female·Age: 18+

Code: NCT07609082

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

for Ovarian Cancer

5 sites incl. Peoria

Sponsor: Nerviano Medical Sciences

Sex: Female·Age: 18+

Code: NCT06930755·Phase 1

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Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing

for Cancer

Sponsor: Unity Health Toronto

Sex: All·Age: 18+

Code: NCT07387263

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QLS5132 Combination Therapy in Advanced Solid Tumors

for Gastric Cancer (GC)

Sponsor: Qilu Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07453394·Phase 1, Phase 2

Cognitive Impact of Neoadjuvant Chemotherapy for Gynecologic Cancers

for Ovarian Cancer

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: Female·Age: 18+

Code: NCT07125209

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18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors

for Clear Cell Renal Cell Cancer (ccRCC)

Sponsor: Peking University First Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07557225

Apply to this trial

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Ovarian cancer clinical trials — common questions

Are ovarian cancer clinical trials free to join?

Yes. Participating in a ovarian cancer clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a ovarian cancer clinical trial?

Each ovarian cancer study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a ovarian cancer trial near me?

Use the location controls above. We'll show recruiting ovarian cancer trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many ovarian cancer trials are recruiting right now?

We're currently tracking roughly 186 recruiting ovarian cancer trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Ovarian cancer trials by city

Birmingham, AL Boston, MA Los Angeles, CA Duarte, CA Tampa, FL Chicago, IL Aurora, CO Denver, CO Orange, CA La Jolla, CA Miami, FL Seattle, WA

Related specialties

Oncology Gynecologic oncology Women's health