Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable Tumours
- Sponsor
- Per Pfeiffer
- Study ID
- NCT01397019
- Phase
- PHASE2
- Status
- Completed
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Oxaliplatin, irinotecan, 5-FU & leucovorin — DRUGFOLFIRINOX followed by 50 gy/27 F in combination with capecitabine in patients with borderline resectable tumors
Study Details
Treating patients with initial local non-resectable pancreatic cancer with a combination of oxaliplatin, irinotecan \& 5-FU(FOLFIRINOX), consolidated with chemoradiotherapy in potentially resectable patients, will result in a high rate of tumor shrinkage allowing subsequent resection in patients with initial borderline resectable tumors and improved overall survival for all patients.
Key Dates
- Start date
- Apr 30, 2011
- Status verified
- Oct 2020
- Primary completion
- Feb 29, 2016
- Completion
- Feb 28, 2018
Study Design
- Enrollment
- 56 participants (actual)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: FOLFIRINOX
Primary Outcome Measure
2 year survival rate [ Time Frame: 2 years ]
Related Studies
- Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic DisordersRecruiting · Mayo Clinic · Phoenix, Arizona
- Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer PatientsRecruiting · Vanderbilt University Medical Center · Nashville, Tennessee
- Pancreatic Adenocarcinoma Gene Environment Risk StudyRecruiting · University of Pittsburgh · Pittsburgh, Pennsylvania
- PANCREATIC DISEASE COHORT A Registry and Biospecimen Bank to Better Understand Pancreatic DiseaseRecruiting · Columbia University · New York, New York