High-dose Aldosterone Antagonist for Acute Decompensated Heart Failure

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The University of Texas Health Science Center at San Antonio
Study ID
NCT02823626
Status
Completed

Conditions

  • Acute Decompensated Heart Failure

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

Primary Aims 1. Evaluate the safety of high-dose spironolactone in combination of patiromer in acute decompensated heart failure patients. 2. Evaluate the efficacy of high-dose spironolactone in combination of patiromer in causing volume loss and symptom relief in patients with ADHF treated with high-dose spironolactone. Secondary Aims 1: Evaluate the effect of high-dose spironolactone on urinary sodium excretion and renal function.

Key Dates

Start date
Sep 30, 2016
Status verified
Apr 2018
Primary completion
Apr 30, 2018
Completion
Apr 30, 2018

Study Design

Enrollment
48 participants (actual)

Arms

  • Arm: Intervention
    Spironolactone and patiromer

Primary Outcome Measure

Weight loss [ Time Frame: up to 10 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
Shweta BansalSan AntonioTexas78229-

Find similar trials in San Antonio, TX

By research site
Shweta Bansal· San Antonio, TX

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