A Study of Nivolumab in Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Bristol-Myers Squibb
Study ID
NCT02857426
Phase
PHASE2
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

The purpose of this study is to determine whether Nivolumab is effective in the treatment of Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Relapsed/Refractory Primary Testicular Lymphoma (PTL)

Key Dates

Start date
Oct 21, 2016
Status verified
Nov 2021
Primary completion
Jun 11, 2019
Completion
Nov 24, 2020

Study Design

Enrollment
66 participants (actual)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Nivolumab for population with PCNSL
    Specified dose on specified days
  • Experimental: Nivolumab for population with PTL
    Specified dose on specified days

Primary Outcome Measure

BICR-Assessed Objective Response Rate (ORR) [ Time Frame: Up to approximately 51 months ]

Locations (13)

FacilityCityStateZIPSite coordinators
University of Alabama at BirminghamBirminghamAlabama35294-3410-
City Of Hope Medical CenterDuarteCalifornia91010-
Mayo Clinic JacksonvilleJacksonvilleFlorida32224-
H. Lee Moffitt Cancer Center & Research Inst, IncTampaFlorida33612-
Dana Farber Cancer InstituteBostonMassachusetts02215-
Massachusetts General HospitalBostonMassachusetts02215-
Karmanos Cancer InstituteDetroitMichigan48201-
Mayo Clinic RochesterRochesterMinnesota55905-
Hackensack University Medical CenterHackensackNew Jersey07601-
Columbia UniversityNew YorkNew York10032-
Fox Chase Cancer CenterPhiladelphiaPennsylvania19111-
Baylor Research InstituteDallasTexas75246-
Swedish Medical CenterSeattleWashington98122-

Find similar trials in Birmingham, AL

By research site
University of Alabama at Birmingham· Birmingham, ALCity Of Hope Medical Center· Duarte, CAMayo Clinic Jacksonville· Jacksonville, FLH. Lee Moffitt Cancer Center & Research Inst, Inc· Tampa, FLDana Farber Cancer Institute· Boston, MAMassachusetts General Hospital· Boston, MA

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