Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
Arjun Balar, MD
Study ID
NCT03272217
Phase
PHASE2
Status
Terminated

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Atezolizumab — DRUG
    Atezolizumab 1200 mg (flat dose) IV every 21 days
  • Bevacizumab — DRUG
    Bevacizumab 15 mg/kg IV every 21 days

Study Details

This is a phase II study assessing the activity of bevacizumab combined with atezolizumab in metastatic urothelial carcinoma patients who are ineligible for cisplatin-based therapy.

Key Dates

Start date
Sep 13, 2017
Status verified
Dec 2024
Primary completion
May 27, 2021
Completion
Mar 17, 2022

Study Design

Enrollment
16 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Arm A - Atezolizumab + Bevacizumab
    Patients will receive atezolizumab 1200 mg (flat dose) IV plus bevacizumab 15 mg/kg IV every 21 days

Primary Outcome Measure

Overall Survival (OS) Rate at 1 Year [ Time Frame: 1 years ]

Locations (8)

FacilityCityStateZIPSite coordinators
University of Arizona at Dignity Health St. JosephPhoenixArizona85004-
Rush University Medical CenterChicagoIllinois60612-
HealthPartners InstituteMinneapolisMinnesota55440-
Memorial Sloan Kettering Cancer CenterNew YorkNew York10065-
New York University Clinical Cancer CenterNew YorkNew York10016-
Cleveland ClinicClevelandOhio44195-
West Cancer Center University of TennesseeMemphisTennessee38120-
Froedtert & The Medical College of WisconsinMilwaukeeWisconsin53226-

Find similar trials in Phoenix, AZ

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Bladder cancer
By specialty
OncologyUrology
By research site
University of Arizona at Dignity Health St. Joseph· Phoenix, AZRush University Medical Center· Chicago, ILHealthPartners Institute· Minneapolis, MNMemorial Sloan Kettering Cancer Center· New York, NYNew York University Clinical Cancer Center· New York, NYCleveland Clinic· Cleveland, OH

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