Bladder cancer Clinical Trials

Recruiting bladder cancer studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat bladder cancer. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting bladder cancer studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting bladder cancer trials

Within

Artificial Intelligence-assisted Uro-Cam Catheter Assessment System for Diagnosing Bladder Cancer

for Bladder Cancer

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 18+

Code: NCT07095751

Evaluation of ATO-101™ in Patients With Non-Muscle-Invasive Bladder Cancer (PERSEVERANCE EU)

for Bladder Cancer

Sponsor: Institut Cancerologie de l'Ouest

Sex: All·Age: 18+

Code: NCT07260162·Phase 1

Hyperthermic Intravesical Chemotherapy (HIVEC) in BCG-Non-Responsive High-Grade NMIBC Patients

for Non Muscle Invasive Bladder Cancer

Sponsor: AC.TA. S.r.l.

Sex: All·Age: 18+

Code: NCT07231809

The Combined Role of FAPI PET and Liquid Biopsy in the Staging and Clinical Management of Bladder Cancer - FUTURE Trial

for Bladder Cancer

Sponsor: Chiti Arturo

Sex: All·Age: 18+

Code: NCT07257718·Phase 2

Imaging Study of [89Zr]DFO-YS5 for Cancer Detection

for Bladder Cancer

1 site in San Francisco

Sponsor: Robert Flavell, MD, PhD

Sex: All·Age: 18+

Code: NCT07664397·Phase 1

PTC-guided Neoadjuvant Therapy For Muscle-invasive Bladder Cancer

for Bladder Cancer

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: All ages

Code: NCT07690878·Phase 2

Sacituzumab Tirumotecan vs MMAE-ADCs in Advanced Urothelial Carcinoma (FUSCC-SPARE-UC-01)

for Bladder Cancer

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT07662863·Phase 2

SL-28 for Advanced Solid Tumours

for Head & Neck Cancer

Sponsor: Second Life Therapeutics

Sex: All·Age: 18+

Code: NCT07341737·Phase 1, Phase 2

Apply to this trial

Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder Cancer

for Bladder Urothelial Carcinoma

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sex: All·Age: 18+

Code: NCT07717242·Phase 2

Apply to this trial

Maintenance AVElumab After SECond Line Platinum-based Chemotherapy for Metastatic Urothelial Carcinoma

for Urothelial Carcinoma

Sponsor: Gruppo Oncologico Italiano di Ricerca Clinica

Sex: All·Age: 18+

Code: NCT07460245·Phase 2

A First-in-Human Study of HH160 in Patients With Advanced Solid Tumors

for Solid Tumor

Sponsor: Huahui Health

Sex: All·Age: 18 - 75

Code: NCT07623369·Phase 1

SYS6002 vs Chemotherapy in Patients With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Carcinoma

Sponsor: CSPC Megalith Biopharmaceutical Co.,Ltd.

Sex: All·Age: 18 - 75

Code: NCT07526792·Phase 3

Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors

for Breast Cancer

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07660055·Phase 1

Apply to this trial

Prehabilitation in High-risk Oncologic Surgery

for Pancreatic Cancer

Sponsor: Fox Chase Cancer Center

Sex: All·Age: 18+

Code: NCT07638410

DBC-664 in Adult Patients With Solid Tumors Associated

for Malignant Germ Cell Tumor

3 sites incl. Grand Rapids

Sponsor: Duboce Biopharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07705035·Phase 1

Apply to this trial

A Study of a Side Effects and Resource Navigation Program for People With Cancer

for Kidney Cancer

8 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07646847

Apply to this trial

Nectin-4 Specific LMW PET Probe Imaging in Urothelial Carcinoma

for Urothelial Carcinoma

Sponsor: Peking University Cancer Hospital & Institute

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05321316

Apply to this trial

Feasibility Study of Urinary cfDNA Analysis as a Non-invasive Monitoring Tool in Patients With Prostate or Bladder Cancer

for Prostate Cancer

Sponsor: Institut Cancerologie de l'Ouest

Sex: All·Age: 18+

Code: NCT07468838

Immune-Stromal Landscape in Muscle-Invasive Bladder Cancer

for Muscle-Invasive Bladder Carcinoma

Sponsor: Assiut University

Sex: All·Age: All ages

Code: NCT07525349

Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial

for Bladder Cancer

Sponsor: Poitiers University Hospital

Sex: All·Age: 18+

Code: NCT07463963

Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors

for Cancer

1 site in New Brunswick

Sponsor: Rutgers, The State University of New Jersey

Sex: All·Age: 18+

Code: NCT06834204

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

for Bladder Cancer

4 sites incl. Traverse City

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07419295·Phase 3

Apply to this trial

Comparison of CT and MR (VI-RADS) Imaging for Local Bladder Cancer Staging

for Bladder Cancer

Sponsor: Oslo University Hospital

Sex: All·Age: 18+

Code: NCT07602010

Apply to this trial

A Study of GEN1106 in Participants With Solid Tumors

for Solid Tumors

4 sites incl. New Haven

Sponsor: Genmab

Sex: All·Age: 18+

Code: NCT07416123·Phase 1

Apply to this trial

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

for Bladder Cancer

1 site in Iowa City

Sponsor: Michael A. O'Donnell

Sex: All·Age: 18 - 99

Code: NCT07322263·Phase 2

Apply to this trial

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

for Diffuse Pleural Mesothelioma

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07532902·Phase 1

Apply to this trial

Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy

for Bladder Cancer

3 sites incl. Tampa

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT07144319

Apply to this trial

Dutasteride in Patients With Low Grade Non-muscle Invasive Bladder Cancer

for Bladder Cancer

Sponsor: Paul Toren

Sex: All·Age: 18+

Code: NCT07420517·Phase 2

Apply to this trial

Urinary Tumor DNA-Guided Systemic Immunotherapy for Unresectable Very-High-Risk Non-Muscle-Invasive Bladder Cancer

for Bladder Cancer

Sponsor: Tianjin Medical University Second Hospital

Sex: All·Age: 18+

Code: NCT07475403·Phase 2

Apply to this trial

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

for Urothelial Cancer

95 sites incl. Fayetteville

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07421700·Phase 1, Phase 2

Apply to this trial

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

for NSCLC Adenocarcinoma

15 sites incl. Santa Rosa

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07277413·Phase 1

Apply to this trial

Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma

for Bladder Cancer

Sponsor: Beijing Biotech

Sex: All·Age: 18 - 75

Code: NCT07492628·Phase 1

Apply to this trial

Detecting CREPT in Urine for Bladder Cancer Diagnosis and Monitoring

for Bladder Cancer

Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07514897

Apply to this trial

Dosing Physical Activity Among Older Cancer Survivors Who Experience Chronic Pain: a Micro-randomized Trial

for Breast Cancer

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 65+

Code: NCT07227077

Apply to this trial

Multiplex Mutation Detection Using Mass Spectrometry in Bladder Cancer

for Bladder Cancer

Sponsor: Zhilong Dong

Sex: All·Age: 18+

Code: NCT07424560

Apply to this trial

Randomized Trial of stAndard of Care With or Without Metastases-directed Stereotactic Body Radiation Therapy in Patients Affected by Oligometastatic uRothelial carcinomA

for Bladder Cancer

Sponsor: Istituto Clinico Humanitas

Sex: All·Age: 18+

Code: NCT07413523

Apply to this trial

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

4 sites incl. San Francisco

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2

Apply to this trial

Cancer Loyalty Card Study 2 (CLOCS-2)

for Pancreatic Cancer

Sponsor: Imperial College London

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06447064

Apply to this trial

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

for Cancer

Sponsor: Essen Biotech

Sex: All·Age: All ages

Code: NCT07410676·Phase 1, Phase 2

Apply to this trial

A Study of Neuropathy Caused by Enfortumab Vedotin in People With Urothelial Carcinoma

for Neuropathy

7 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07390617

Apply to this trial

Circulating Tumor DNA Response In Urothelial Cancer

for Urothelial Carcinoma

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+

Code: NCT07183319·Phase 2

Apply to this trial

Evaluation of the Clinical Utility of Online Adaptive Radiotherapy in Bladder Cancer (BLADAPT-GETUG V11)

for Bladder Cancer

Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

Sex: All·Age: 18+

Code: NCT07043543

Supporting Sexual Health in Bladder Cancer Patients: A Sequential Mixed-Methods Intervention Study

for Bladder Cancer

Sponsor: University of Aarhus

Sex: All·Age: 18+

Code: NCT07339761

Apply to this trial

Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy

for Bladder Cancer

2 sites in Philadelphia

Sponsor: Thomas Jefferson University

Sex: All·Age: 18 - 85

Code: NCT07234968

Apply to this trial

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

for Amyloidosis

1 site in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07285044·Phase 2

Apply to this trial

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

for Bladder Cancer

2 sites incl. Bakersfield

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07222488·Phase 1, Phase 2

Apply to this trial

Toripalimab Combined With BCG Perfusion for the Treatment of HR-NMIBC After TURBT Surgery Exploration

for Bladder Cancer

Sponsor: Changhai Hospital

Sex: All·Age: 18 - 75

Code: NCT07307456·Phase 2

Apply to this trial

Validity of Parametric MRI Using VIRADS

for Bladder Cancer

Sponsor: Assiut University

Sex: All·Age: All ages

Code: NCT05783271

Apply to this trial

Entinostat & Chemotherapy for Locally Advanced or Metastatic Bladder Cancer

for Bladder Cancer

Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Sex: All·Age: 18 - 75

Code: NCT07261592·Phase 1, Phase 2

Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC)

for Urothelial Carcinoma

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07241793·Phase 2

Apply to this trial

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

12 sites incl. Duarte

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1

Apply to this trial

Study on the Effects of Drugs That Modulate the Endocannabinoid System on Spontaneous and Induced Contractility of the Human Detrusor Muscle

for Bladder Cancer

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07545694

Apply to this trial

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

for Bladder Cancer

6 sites incl. Tampa

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT07225127

Apply to this trial

Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study

for Bladder Cancer

Sponsor: Western University, Canada

Sex: All·Age: 18+

Code: NCT07204301

Home Intravenous Fluid Infusion After Undergoing Radical Cystectomy

for Bladder Cancer

2 sites in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07225205

Apply to this trial

A Clinical Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.

for Bladder Cancer

Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Sex: All·Age: 18+

Code: NCT06364904·Phase 3

Characterizing the Microvascular Environment of Bladder Cancer With Super-Resolution Ultrasound Localization Microscopy

for Bladder Cancer

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT06986304

Apply to this trial

Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?

for Hematuria

Sponsor: Vastra Gotaland Region

Sex: Female·Age: 18 - 110·Accepts healthy volunteers

Code: NCT07037589

Apply to this trial

Guiding Value of Urinary Tumor DNA Testing in Repeat Transurethral Resection of Non-Muscle-Invasive Bladder Cancer

for Bladder Cancer

Sponsor: Tianjin Medical University Second Hospital

Sex: All·Age: 18+

Code: NCT07187635

Apply to this trial

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Cancer

7 sites incl. Los Angeles

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07129993·Phase 2, Phase 3

Apply to this trial

Bladder cancer clinical trials — common questions

Are bladder cancer clinical trials free to join?

Yes. Participating in a bladder cancer clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a bladder cancer clinical trial?

Each bladder cancer study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a bladder cancer trial near me?

Use the location controls above. We'll show recruiting bladder cancer trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many bladder cancer trials are recruiting right now?

We're currently tracking roughly 139 recruiting bladder cancer trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Bladder cancer trials by city

Los Angeles, CA Boston, MA San Francisco, CA Duarte, CA Birmingham, AL Chicago, IL Denver, CO Gainesville, FL Jacksonville, FL Orange, CA Tampa, FL Ann Arbor, MI

Related specialties

Oncology Urology