Improving Uptake and Adherence to HIV Prevention Services With Pre-exposure Prophylaxis (PrEP), HIV Self- Testing and Adherence Support for Very High Risk HIV-negative Young Women Aged 15-24 in Kampala, Uganda

Sponsor
University of California, San Francisco
Study ID
NCT04030520
Status
Completed

Conditions

Eligibility Criteria

Sex
FEMALE
Age
15 Years - 24 Years
Healthy Volunteers
Accepted

Interventions

  • POPPi — BEHAVIORAL
    behavioral intervention with offer of HIV self test
  • Comparison — BEHAVIORAL
    standard of care

Study Details

The main aim is to develop and assess an intervention to enhance initiation and adherence to PrEP among HIV negative young women of high risk (YWHR). The specific aims are (1) To conduct formative research to enhance our understanding of the dynamics of the social and sexual networks, and context of young HIV-uninfected women (aged 15-24) engaged in high risk sexual behavior in Kampala, Uganda (2) Document barriers and opportunities for PrEP uptake and adherence as well as repeat HIV testing by self test; (3) To develop and test a socially and culturally acceptable and feasible prevention intervention on uptake and adherence to PrEP and HIV self-testing for young women at high risk for HIV.

Key Dates

Start date
Jul 8, 2019
Status verified
Jul 2025
Primary completion
Oct 31, 2020
Completion
Oct 31, 2021

Study Design

Enrollment
60 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: intervention
    participants will receive a behavioral intervention including counseling and offer of HIV oral fluid self test and PrEP
  • Active Comparator: comparison
    participants will be not be offered HIV oral fluid self test but receive counseling, condoms and offered PrEP

Primary Outcome Measure

Initiation of PrEP [ Time Frame: 6 months ]

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