Infectious disease Clinical Trials

Recruiting infectious disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat infectious disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting infectious disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting infectious disease trials

Within

Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans

for Opioid Use Disorder

1 site in Northport

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06766331

Same-Day Antiretroviral Therapy as a Behavioral Design Intervention to Reduce Stigma in Key Affected Populations

for Hiv

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07053514

Extended vs. Intermittent Meropenem Infusion in Sepsis Patients in the ICU

for Sepsis

Sponsor: Assiut University

Sex: All·Age: 18 - 65

Code: NCT07398703

Healthy Choices to Reduce Stigma and Improve Self-Management of Alcohol and HIV Among Young Adults

for HIV

1 site in Tallahassee

Sponsor: Florida State University

Sex: All·Age: 18 - 29

Code: NCT07638618

Intervention to Reduce Implicit Bias in Pharmacies

for Bias, Implicit

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06487351

Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in Florida

for Hiv

1 site in Tallahassee

Sponsor: Florida State University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06015581

PrEPwise Pilot Among Black Women in Eastern Virginia

for HIV Infections

1 site in Norfolk

Sponsor: Boston University

Sex: Female·Age: 18+

Code: NCT07398482

Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior

for HIV

1 site in Atlanta

Sponsor: Emory University

Sex: Male·Age: 18 - 30

Code: NCT07769580

Implementation Science to Enhance HIV Testing Services During Emergency Care in Kenya

for HIV

Sponsor: Rhode Island Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06747221

HIV Self-Testing and Long-Acting Injectables for HIV Treatment and Prevention Among Commercial Minibus Drivers (I-TEST LAIs) in Nigeria

for HIV

Sponsor: George Washington University

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT07000513·Phase 4

The Extended Study of Prevalence of Infection in Intensive Care IV

for Sepsis

Sponsor: Universidad de la Sabana

Sex: All·Age: 18+

Code: NCT07309549

Integrated Health Services (IHS): A Structural Intervention to Improve HIV/STI Screening and PrEP Navigation in Primary Care

for HIV

1 site in Ridgeland

Sponsor: My Brother's Keeper, Inc.

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07446764

Yuva Sath: A Peer-led Behavioral Intervention to Support Substance Use Treatment and HIV Prevention Among Young People Who Inject Drugs in India

for Hiv

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 29

Code: NCT06510192

A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs

for Substance Use

3 sites incl. Los Angeles

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07409350

Safety and Efficacy of Low-dose Anticoagulation With Argatroban and Enoxaparin on ECMO

for Pneumonia

Sponsor: University Hospital Ostrava

Sex: All·Age: 18+

Code: NCT07499037·Phase 2

Leveraging Pharmacy Technicians to Advance the Reach of Modern Antiretroviral Therapy (PHARM ART) in Community Clinics

for HIV

Sponsor: University of Chicago

Sex: All·Age: 15+

Code: NCT07553949

Evaluation of the Safety and Efficacy of XoGlo Pro, a Placental Mesenchymal Stem Cell-derived Extracellular Vesicles in Treating COVID-19 Symptoms

for COVID-19

Sponsor: Kimera Labs Inc.

Sex: All·Age: 18+

Code: NCT07664696·Phase 1, Phase 2

Decision Support Tool to Integrate PrEP Into Emergency Departments

for HIV

2 sites incl. Washington D.C.

Sponsor: George Washington University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07279129·Phase 1

Biological Effects of Hemoadsorption in Septic Shock

for Septic Shock, Vasopressor Resistance

Sponsor: Miguel Sanchez Garcia

Sex: All·Age: 18+

Code: NCT07715110

Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers

for Cryptococcal Antigenemia

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07743593·Phase 3

Improving HIV Prevention and Substance Use Post-Sexual Assault Services

for HIV Infections

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 17 - 25

Code: NCT07225062

Are Louisiana Pharmacists PrEPared? Implementing Training and an Active PrEP (Pre-Exposure Prophylaxis) Prescribing Surveillance Program

for HIV Prevention

1 site in New Orleans

Sponsor: Xavier University of Louisiana.

Sex: All·Age: 24 - 99

Code: NCT06530225

Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress

for Critical Illness

3 sites incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18+

Code: NCT07634419

Optimizing Implementation of Long Acting Injectable PrEP

for HIV Infections

Sponsor: University of Minnesota

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07649551

Immune Dysregulation During Sepsis: A Natural History Cohort

for Sepsis

1 site in Falls Church

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 100

Code: NCT07735741

Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

for Sepsis

1 site in Houston

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT01315782

Implementation of PrEP Care Among Women in Family Planning Clinics

for PrEP Uptake

Sponsor: Rush University Medical Center

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06335121

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

for HIV-1-infection

10 sites incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT06987318·Phase 1

HEME-25: Open-Label Feasibility Study of Elranatamab Utilized in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV

for Plasmablastic Lymphoma

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07647432·Phase 2, Phase 3

Fatigue in Long COVID

for Long COVID

Sponsor: McMaster University

Sex: All·Age: 18 - 65

Code: NCT07697261

Combating HIV Stigma in Healthcare Settings: A Standardized Patient Approach

for Hiv

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06975176

Assessing Role of Probiotics in Children Aged 6-36 Months Treated for Pneumonia

for Pneumonia

Sponsor: Anabio R&D

Sex: All·Age: 6 Months - 36 Months

Code: NCT07399717

Theoretically Informed Behavioral Intervention

for HIV

1 site in Orange

Sponsor: Yale University

Sex: Male·Age: 18+

Code: NCT06580184

Peer-led Community-based PrEP Delivery Among Youth in Brazil

for Pre-Exposure Prophylaxis (PrEP)

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 15 - 24·Accepts healthy volunteers

Code: NCT06661356

People & Place: Impacts on Substance Use and HIV Outcomes in Los Angeles

for HIV

Sponsor: University of California, Los Angeles

Sex: Male·Age: 18+

Code: NCT07200973

Baricitinib Curative Repression of HIV-1

for HIV Infection

2 sites in Atlanta

Sponsor: Emory University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07209267·Phase 2

STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis

for Sepsis

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT07332325·Phase 3

DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and Botswana

for HIV Infections

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07597824

Light-based Immunomodulation for Guarding Against Human Respiratory Tract Infections

for COVID-19 Respiratory Infection

Sponsor: David Moss

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07610967

Biomarkers for Post-treatment Control in HIV: International Study of the EU2Cure Research Consortium (Phase I)

for HIV

Sponsor: Erasmus Medical Center

Sex: All·Age: 16+·Accepts healthy volunteers

Code: NCT07692295

Adaptation and Evaluation of an Intersectional Stigma Reduction Intervention to Increase HIV Care Engagement Among Women Who Use Drugs

for HIV

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: Female·Age: 18+

Code: NCT07751978

PrEP & Soccer: A Program for Pharmacy Chains to Increase PrEP Awareness and Access Among Men

for HIV Prevention

1 site in Miami

Sponsor: University of Miami

Sex: Male·Age: 18 - 54

Code: NCT07263048

Ulinastatin on Systemic Immune-Inflammation in Patients With Complicated Intra-Abdominal Infection

for Complicated Intra-abdominal Infection (cIAI)

Sponsor: Fujian Medical University Union Hospital

Sex: All·Age: 18+

Code: NCT07672496

EARLY-SARDS: Early AlveolaR Lung biologY Underling Sepsis-Associated ARDS

for Acute Hypoxemic Respiratory Failure

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

Sex: All·Age: 18+

Code: NCT07281911

A Study of SYH2085 Tablets Compared With Placebo in Chinese Adult Patients With Uncomplicated Influenza.

for Influenza

Sponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Sex: All·Age: 18+

Code: NCT07798193·Phase 2

Digital Intervention Delivered Via Street Medicine to Increase HIV and Substance Use Care Among Survivors of Sex Trafficking

for Sex Trafficking

1 site in Providence

Sponsor: Lifespan

Sex: Female·Age: 18+

Code: NCT07699484·EARLY_Phase 1

Ketogenic Approach to Restore Muscle in Older Patients With Community-Acquired Pneumonia - KARMA-P Trial

for Pneumonia

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 55+

Code: NCT07308483

TelePharm PrEP/PEP

for HIV

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 15+·Accepts healthy volunteers

Code: NCT07561658

INTEGRATE-RX: Integrating Clinical Pharmacists in HIV Care to Mitigate Last-Mile Challenges and Reduce Cardiovascular Disease Burden

for HIV

Sponsor: Temple University

Sex: All·Age: 18 - 75

Code: NCT07711366

Paclitaxel and Pegylated Liposomal Doxorubicin for Treatment of HIV-related Kaposi Sarcoma

for Kaposi Sarcoma

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05411237·Phase 3

Developing an HIV Disclosure Intervention for Men in Uganda

for HIV Infections

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT05771519

Confidential Care and Adolescent HIV Testing

for Hiv

Sponsor: Yale University

Sex: All·Age: 13 - 17

Code: NCT06279949

Development of a Multilevel HIV Prevention Intervention for the Emergency Department

for HIV

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06331767

Leveraging Video Logs as a Bridge to Pre-exposure Prophylaxis (PrEP) With Tailored Messaging to Black Women and Their Healthcare Providers in Texas.

for HIV Prevention

1 site in Galveston

Sponsor: The University of Texas Medical Branch, Galveston

Sex: Female·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06864689·EARLY_Phase 1

HIV Testing in Community Health Center Dental Clinics

for HIV

4 sites incl. Boston

Sponsor: Boston University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07089849

Harmonized Healing: Personalized Music Interventions to Address Chronic Pain in People Living With HIV

for Chronic Pain

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07214077

C11 ER176 PET in Evaluating Neuroinflammation in Patients With Post-COVID Syndrome

for COVID-19

1 site in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07527130

Adjuvant 5-Fluorouracil Following Thermal Ablation to Improve HPV Treatment Outcomes in Women With HIV in Kenya

for HIV Infections

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female·Age: 25+

Code: NCT07545746·Phase 2

Clinic vs Clinic+Community Outreach HPV Self-Collection to Increase Cervical Screening in Women Living With HIV

for Cervix Cancer

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: Female·Age: 25 - 49

Code: NCT07624123

Evaluation of biomArkers for Quick SEpsis Diagnosis - ErASED Study

for Sepsis

Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia

Sex: All·Age: 18+

Code: NCT07655154

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Infectious disease clinical trials — common questions

Are infectious disease clinical trials free to join?

Yes. Participating in a infectious disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a infectious disease clinical trial?

Each infectious disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a infectious disease trial near me?

Use the location controls above. We'll show recruiting infectious disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many infectious disease trials are recruiting right now?

We're currently tracking roughly 469 recruiting infectious disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Infectious disease trials by city

San Francisco, CA Birmingham, AL Boston, MA Chicago, IL Miami, FL Los Angeles, CA San Diego, CA Indianapolis, IN Gainesville, FL Oakland, CA Seattle, WA Aurora, CO

Conditions in this area

HIV COVID-19 / long COVID Influenza Pneumonia Sepsis Infections (general)