Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation

Part of paid clinical trials in San Antonio, Texas.

Sponsor
University of the Incarnate Word
Study ID
NCT04234932
Phase
EARLY_PHASE1
Status
Unknown

Conditions

  • Glaucoma, Open-Angle

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Netarsudil Ophthalmic — DRUG
    Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)

Study Details

Investigate changes in optical coherence tomography angiography of the optic nerve and macula following topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution.

Key Dates

Start date
Jan 6, 2020
Status verified
Apr 2020
Primary completion
Jan 31, 2021
Completion
Jan 31, 2021

Study Design

Enrollment
10 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Netarsudil alone
    Topical application of netarsudil 0.02%
  • Active Comparator: Netarsudil plus latanoprost
    Topical application of netarsudil 0.02% with latanoprost 0.005%

Primary Outcome Measure

Peripapillary capillary perfusion density [ Time Frame: 90 minutes ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of the Incarnate WordSan AntonioTexas78209
Ana C Hagendorf, PhD
[email protected]
210-805-3036

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By research site
University of the Incarnate Word· San Antonio, TX

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