Early Ageing During Therapy in AYA Cancer Patients

Sponsor
University Medical Center Groningen
Study ID
NCT05062707
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 39 Years
Healthy Volunteers
Not accepted

Interventions

  • Blood sampling — PROCEDURE
    Study measurements will be performed twice and consist of blood withdrawal and physical examination (weight, height, waist-hip ratio, and blood pressure).

Study Details

Longitudinal cohort study; measurements before start of systemic therapy and one year later.

Key Dates

First listed
Sep 30, 2021
Start date
Feb 10, 2022
Status verified
May 2025
Primary completion
Jul 31, 2025
Completion
Jul 31, 2025

Study Design

Enrollment
120 participants (estimated)

Arms

  • Arm: AYA cancer patients
    Patients aged 18-39 years, with a first histological and/or cytological diagnosis of a haematological or solid malignancy, scheduled to start systemic therapy with curative intent.

Primary Outcome Measure

Change in senescence marker P16 [ Time Frame: at baseline and 1 year after start systemic therapy ]

Central Contacts

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