Breast oncology Clinical Trials

Recruiting breast oncology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat breast oncology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting breast oncology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting breast oncology trials

Within

Application of Multimodal MRI-based Radiomics in Histological Grading and Prognostic Assessment of Breast Cancer

for Breast Cancer

Sponsor: Hao Xu

Sex: Female·Age: All ages

Code: NCT07389200

Gut Microbiome Changes During Abemaciclib Therapy in Breast Cancer

for Breast Cancer

1 site in Burlington

Sponsor: University of Vermont Medical Center

Sex: Female·Age: 18+

Code: NCT07406594

EmpowerHer: Hybrid Digital Intervention for Breast Cancer Survivors

for Breast Cancer

Sponsor: University of Valencia

Sex: Female·Age: 18 - 65

Code: NCT07676591

Korea Post Marketing Surveillance (PMS) Study of Talzenna®

for Breast Neoplasms

Sponsor: Pfizer

Sex: All·Age: 19+

Code: NCT04982848

Early Intervention

for Breast Cancer

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT05326165

Strategies to Decentralize Breast Ultrasound in Rwanda

for Breast Cancer

Sponsor: Brigham and Women's Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06812208

Remotely Supervised Exercise During Chemotherapy in Women With Breast Cancer

for Breast Cancer

Sponsor: Riga Stradins University

Sex: Female·Age: 30 - 65

Code: NCT07716306

Phase I/II, Evaluate the Safety and Efficacy of BLEX 404 With Docetaxel in Patients With Advanced/Metastatic Triple Negative Breast Cancer.

for Triple Negative Breast Cancer

Sponsor: BioLite, Inc.

Sex: Female·Age: 20 - 70

Code: NCT02802423·Phase 1, Phase 2

A Study to Learn More About Tukysa Once it is Out in the Korean Market

for HER2-positive Locally Advanced Unresectable

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06873191

Optimizing Functional Recovery After Breast Cancer Treatment

for Breast Neoplasms

1 site in Boston

Sponsor: MGH Institute of Health Professions

Sex: All·Age: 18+

Code: NCT07489053

ctDNA-Guided Intraventricular Therapy for CNS Malignancies

for Leptomeningeal Disease

Sponsor: Alireza Mansouri

Sex: All·Age: 18 - 120

Code: NCT07689721

Wearable Device Tracked Recovery From Autologous Breast Reconstructive Surgery

for Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07631026

ORASIS in Breast Reconstruction

for DIEP Flap

2 sites incl. Durham

Sponsor: Duke University

Sex: Female·Age: 18+

Code: NCT07670754

Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care

for Breast Carcinoma

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07690852

Study to Understand Relationship Between Gut Health and Toxicities of Hormonal Breast Cancer Treatment

for Breast Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07553234

Blood and imagE-guided Optimization of Neoadjuvant Therapy in People With Early Stage Triple-negative Breast cancER - the BETTER Trial

for Triple Negative Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07610525·Phase 2

Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)

for Breast Cancer

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07255612·Phase 2

Breast and Cervical Cancer Stigma in Rwanda

for Breast Cancer

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT07663006

A Study of the TheraBionic P1 Device in Breast Cancer

for Breast Cancer Stage I

8 sites incl. Clarkston

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: Female·Age: 22+

Code: NCT07218432

Apply to this trial

Self-management Interventions to Reduce Cardiovascular Risks in Breast Cancer Survivors

for Breast Cancer

Sponsor: University of Southern Queensland

Sex: Female·Age: 18+

Code: NCT07313397

Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled Trial

for COPE

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07610499

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

2 sites incl. Boston

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1

Apply to this trial

A Phase II Study of Zongertinib Plus Fulvestrant in Participants With HR-positive/HER2-negative Advanced Breast Cancer Harboring HER2 Mutations.

for Advanced Breast Cancer

Sponsor: MedSIR

Sex: All·Age: 18+

Code: NCT07619066·Phase 2

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

for Anatomic Stage IV Breast Cancer AJCC v8

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06982222·Phase 1

ctDNA-Guided Chemotherapy Omission With Ribociclib Plus Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer

for Breast Cancer

Sponsor: Fudan University

Sex: Female·Age: 18 - 70

Code: NCT07423611·Phase 2

Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast Cancers

for Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07553390·Phase 1

Ultrasound-Guided Core Needle Biopsy to Assess Sensitivity and Specificity of Axillary Lymph Node Metastasis in Breast Cancer

for Lymphatic Metastasis

Sponsor: The First Hospital of Jilin University

Sex: Female·Age: 18 - 70

Code: NCT07573657

An Open-Label, Randomized Phase III Study of Trastuzumab Rezetecan With or Without Bevacizumab in First to Third Line BLIS Subtype TNBC

for Breast Cancer

Sponsor: Fudan University

Sex: Female·Age: 18 - 70

Code: NCT07669610·Phase 3

CRYO-TOUCH: Cryoablation of the Primary Breast Tumor in Metastatic Breast Cancer

for Metastatic Breast Cancer

Sponsor: Hospices Civils de Lyon

Sex: Female·Age: 18+

Code: NCT07676344

Fulvestaciclib Combined With Anti-HER2 and Endocrine Therapy for HR+/HER2+ Advanced Breast Cancer

for Breast Cancer

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT07716046·Phase 2

REstoring Metabolic FLEXibility Through Combined Exercise in Breast Cancer Survivors: A Randomized Controlled Trial.

for Cancer

Sponsor: University of Castilla-La Mancha

Sex: Female·Age: 18 - 70

Code: NCT07405385

Pharmacokinetic Model of Abemaciclib: Correlation With Severe Diarrhea as the Primary Toxicity Endpoint in Patients With Localized Hormone Receptor-positive Breast Cancer

for Abemaciclib

Sponsor: Poitiers University Hospital

Sex: Female·Age: 18+

Code: NCT07490509·Phase 4

Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Aromatase Inhibitor-induced Arthralgia (AIA)

for Breast Cancer

Sponsor: Institut Cancerologie de l'Ouest

Sex: Female·Age: 18+

Code: NCT07575750

Study of the TheraBionic P1 Device in Patients With Metastatic Triple Negative Breast Cancer After Progression

for Triple Negative Breast Cancer

1 site in Detroit

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: Female·Age: 22+

Code: NCT07672431

SHIELD: Surveillance of HR+/HER2- : Implementing ESR1m Long-term Monitoring and Detection in 1L aBC

for Advanced Breast Cancer

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07701070

Adjuvant Endocrine Therapy Adherence Intervention Pilot in Rwanda

for Medication Adherence

3 sites in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT07562399

Sexual Health and Rehabilitation for Women With Metastatic Breast Cancer (SHARE-MC): An Educational Intervention

for Metastatic Breast Cancer

1 site in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT07519200

CBD for Breast Cancer Primary Tumors

for Breast Cancer

1 site in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06148038·Phase 1

Apply to this trial

Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer

for Breast Cancer

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07217990·Phase 1, Phase 2

Effect of Hypnosis in the Management of Anxiety and Chemo-induced Symptoms in Adolescents and Young Adults With Sarcoma or Germ Cell Tumor and in Young Women With Breast Cancer

for Sarcoma

Sponsor: Institut Bergonié

Sex: All·Age: 15 - 49

Code: NCT07614620

Randomized Double-Blind Phase II Trial of Baby Exemestane Versus Baby Tamoxifen in Post-Menopausal Women at High Risk for Breast Cancer

for Breast Cancer

2 sites in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: All ages

Code: NCT07499999·Phase 2

T-DXd Based Therapy Followed by Endocrine Therapy Plus Dual HER2 Blockade in First-line HER2+/ HR+ Metastatic Breast Cancer and Retreatment With T-DXd

for Advanced Breast Cancer

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07683754·Phase 3

The Effect of Video-Assisted Mindfulness-Based Breathing on Quality of Life and Mental Well-Being in Individuals With Breast Cancer

for Breast Cancer

Sponsor: Ege University

Sex: All·Age: 18+

Code: NCT07575386

Preventing Breast Cancer Therapy-related Cardiovascular Toxicity With a Daily-adapted Program With Mhealth Support

for Breast Cancer Female

Sponsor: Universidad de Granada

Sex: Female·Age: 18 - 65

Code: NCT06518200

Efti in Patients With Hormone Receptor Positive/HER2-neg Breast Cancer

for Breast Cancer

Sponsor: George Washington University

Sex: All·Age: 21+

Code: NCT07102940·Phase 2

Wearable Ultrasound Patch for Breast Imaging

for Breast Cancer

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07186491

HISMAR: Intraoperative Margin Assessment Using the Histolog® Scanner to Reduce Reoperation in Breast-Conserving Surgery

for Breast Cancer

Sponsor: Hôpital du Valais

Sex: Female·Age: 18+

Code: NCT07527468

Evaluation of [68Ga]Ga-NOTA-anti-HER2-sdAb PET/CT for Predicting Pathological Complete Response After Neoadjuvant Chemotherapy in HER2 Positive Early Breast Cancer

for Breast Cancer

Sponsor: Centre Henri Becquerel

Sex: Female·Age: 18+

Code: NCT07593976·Phase 2

Adherence and Safety of Ribociclib Plus Aromatase Inhibitors in Patients With Early Stage, HR+ and HER2- Breast Cancer

for Breast Cancer

Sponsor: Institute of Oncology Ljubljana

Sex: All·Age: 18+

Code: NCT07630948·Phase 4

Cancer Lipidome Adaptation and Resculping Through Omega-3 PUFAs in Breast Tumors

for Breast Cancer

1 site in Milwaukee

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT07643428·Phase 2

Safety, Feasibility, and Outcomes of Early Rehabilitation After Breast Cancer Surgery

for Breast Cancer Female

Sponsor: Marta Aguilar-Rodriguez

Sex: Female·Age: 18+

Code: NCT07651696

Single FrAction Interstitial BreaSt BracHytherApy

for Breast Cancer

1 site in Richmond

Sponsor: Virginia Commonwealth University

Sex: Female·Age: 40 - 85

Code: NCT07654257·Phase 2

INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE Study

for Breast Cancer

3 sites incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07671937

Surgery vs. No Surgery for Primary Tumor in De Novo Stage IV Breast Cancer With Solitary Bone Metastases

for Breast Cancer

Sponsor: West China Hospital

Sex: Female·Age: 18 - 70

Code: NCT07687225

Effects, Metabolic Mechanisms and Predictors of Response to Acupuncture in Treating Psychoneurological Symptoms Among Breast Cancer Survivors

for Breast Cancer

1 site in Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 18+

Code: NCT07695948·Phase 3

Utility of a Mobile Application for Young Women With Breast Cancer

for Breast Cancer

1 site in Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07009093

Apply to this trial

Respiratory Muscle Strength Training to Prevent Respiratory Muscle Weakness in Adults Newly Diagnosed With Breast Cancer

for Breast Cancer

1 site in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 100

Code: NCT07229378

Precision Supplemental Imaging in Women With Dense Breasts

for Breast Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 25 - 55·Accepts healthy volunteers

Code: NCT07277738

Systemic Anti-Cancer Therapy Dose Modifications for Individuals With Duffy Null Phenotype

for Multiple Myeloma

1 site in Boston

Sponsor: Andrew Hantel, MD

Sex: All·Age: 18+

Code: NCT07341867·Phase 1

Evaluation of the Impact of Pre-habilitation Using Physiotherapy and Mechanical Stimulation on Shoulder Pain and Mobility in Patients Undergoing Breast Reconstruction Using a Latissimus Dorsi Flap

for Breast Cancer

Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle

Sex: Female·Age: 18+

Code: NCT07418060

Breast oncology clinical trials — common questions

Are breast oncology clinical trials free to join?

Yes. Participating in a breast oncology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a breast oncology clinical trial?

Each breast oncology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a breast oncology trial near me?

Use the location controls above. We'll show recruiting breast oncology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many breast oncology trials are recruiting right now?

We're currently tracking roughly 953 recruiting breast oncology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Breast oncology trials by city

Boston, MA Los Angeles, CA Birmingham, AL Duarte, CA San Francisco, CA Chicago, IL Tampa, FL Columbus, OH Gainesville, FL Jacksonville, FL Salt Lake City, UT Aurora, CO

Conditions in this area

Breast cancer Metastatic breast cancer Triple-negative breast cancer HER2-positive breast cancer HER2-negative breast cancer