Breast oncology Clinical Trials

Recruiting breast oncology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat breast oncology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting breast oncology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting breast oncology trials

Within

Application of Multimodal MRI-based Radiomics in Histological Grading and Prognostic Assessment of Breast Cancer

for Breast Cancer

Sponsor: Hao Xu

Sex: Female·Age: All ages

Code: NCT07389200

Gut Microbiome Changes During Abemaciclib Therapy in Breast Cancer

for Breast Cancer

1 site in Burlington

Sponsor: University of Vermont Medical Center

Sex: Female·Age: 18+

Code: NCT07406594

Developing and Testing the Efficacy of AI-Chatbot-Based

for Breast Cancer

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18+

Code: NCT07791368

EmpowerHer: Hybrid Digital Intervention for Breast Cancer Survivors

for Breast Cancer

Sponsor: University of Valencia

Sex: Female·Age: 18 - 65

Code: NCT07676591

Monitoring Breast Cancer Immunotherapy Treatment With Advanced Positron Emission Tomography Magnetic Resonance Imaging (PET/MRI)

for Triple Negative Breast Cancer

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 75

Code: NCT04861077·EARLY_Phase 1

Apply to this trial

Multi-4SCAR-T Therapy Targeting Breast Cancer

for Breast Cancer

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 75

Code: NCT04430595·Phase 1, Phase 2

Korea Post Marketing Surveillance (PMS) Study of Talzenna®

for Breast Neoplasms

Sponsor: Pfizer

Sex: All·Age: 19+

Code: NCT04982848

Early Intervention

for Breast Cancer

1 site in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT05326165

A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

11 sites incl. Arcadia

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT07741968

Apply to this trial

Strategies to Decentralize Breast Ultrasound in Rwanda

for Breast Cancer

Sponsor: Brigham and Women's Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06812208

Remotely Supervised Exercise During Chemotherapy in Women With Breast Cancer

for Breast Cancer

Sponsor: Riga Stradins University

Sex: Female·Age: 30 - 65

Code: NCT07716306

Phase I/II, Evaluate the Safety and Efficacy of BLEX 404 With Docetaxel in Patients With Advanced/Metastatic Triple Negative Breast Cancer.

for Triple Negative Breast Cancer

Sponsor: BioLite, Inc.

Sex: Female·Age: 20 - 70

Code: NCT02802423·Phase 1, Phase 2

A Study to Learn More About Tukysa Once it is Out in the Korean Market

for HER2-positive Locally Advanced Unresectable

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06873191

Optimizing Functional Recovery After Breast Cancer Treatment

for Breast Neoplasms

1 site in Boston

Sponsor: MGH Institute of Health Professions

Sex: All·Age: 18+

Code: NCT07489053

ctDNA-Guided Intraventricular Therapy for CNS Malignancies

for Leptomeningeal Disease

Sponsor: Alireza Mansouri

Sex: All·Age: 18 - 120

Code: NCT07689721

Wearable Device Tracked Recovery From Autologous Breast Reconstructive Surgery

for Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07631026

ORASIS in Breast Reconstruction

for DIEP Flap

2 sites incl. Durham

Sponsor: Duke University

Sex: Female·Age: 18+

Code: NCT07670754

Evaluation of the Safety and Efficacy of Single-Port Robot-Assisted Endoscopic Breast-Conserving Surgery and Nipple-sparing Matectomy With Reconstruction in Early-Stage Breast Cancer Patients

for Breast Cancer

Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

Sex: Female·Age: 18 - 80

Code: NCT07781163

Environmental Exposure Assessment in High-Risk and Early-Onset Breast Cancer Care

for Breast Carcinoma

1 site in Duarte

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07690852

Apply to this trial

Study to Understand Relationship Between Gut Health and Toxicities of Hormonal Breast Cancer Treatment

for Breast Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07553234

A Study of LG00313112 in Participants With Advanced Solid Malignancies Harboring a TP53 Y220C Mutation

for Ovarian Cancer

Sponsor: LG Chem

Sex: All·Age: 18+

Code: NCT07752875·Phase 1, Phase 2

Percutaneous Cryoablation for the Treatment of Breast Cancer

for Breast Cancer

Sponsor: Ospedale Cottolengo

Sex: Female·Age: 18+

Code: NCT07775014

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

for Breast Carcinoma

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07606287

Tucatinib Continuation Study

for HER2-positive Breast Cancer

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07768358·Phase 4

Blood and imagE-guided Optimization of Neoadjuvant Therapy in People With Early Stage Triple-negative Breast cancER - the BETTER Trial

for Triple Negative Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07610525·Phase 2

Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)

for Breast Cancer

Sponsor: Sun Yat-sen University

Sex: All·Age: 18+

Code: NCT07255612·Phase 2

Breast and Cervical Cancer Stigma in Rwanda

for Breast Cancer

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT07663006

Single vs Multiple Injection Intertransverse Process Block in Breast Cancer Surgery

for Breast Cancer

Sponsor: Antalya City Hospital

Sex: Female·Age: 18 - 65

Code: NCT07763756

DiEtary Mimicry by Glucocorticoid Modulation Evaluation in ER+ Metastatic Breast Cancer Treatment: Efficacy and Response (DEMETER Trial)

for Breast Cancer

Sponsor: The Netherlands Cancer Institute

Sex: Female·Age: 18+

Code: NCT07786051·Phase 2

Herbs & Supplements in Breast Cancer Usage, Impact, and Personalized Approaches for Diverse Populations

for Breast Cancer

2 sites incl. Weston

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06926530

A Study of the TheraBionic P1 Device in Breast Cancer

for Breast Cancer Stage I

8 sites incl. Clarkston

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: Female·Age: 22+

Code: NCT07218432

Apply to this trial

Self-management Interventions to Reduce Cardiovascular Risks in Breast Cancer Survivors

for Breast Cancer

Sponsor: University of Southern Queensland

Sex: Female·Age: 18+

Code: NCT07313397

Feasibility of 'Exercise for CAncer Patients and Healthy EAting Timeframes' .

for Breast Cancer

1 site in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT07529353

Overcoming Racial Disparities in Screening Mammography

for Breast Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 40+·Accepts healthy volunteers

Code: NCT07549139

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

for Pancreas Cancer

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07732686

Researching the Effect of Exercise on Cancer

for Breast Cancer

2 sites incl. Durate

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04589468

Apply to this trial

Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled Trial

for COPE

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: Female·Age: 18+

Code: NCT07610499

Implementing a Digital Alcohol Intervention to Raise Women's Awareness of Alcohol-related Breast Cancer Risk During Routine Screening Visits

for Breast Cancer

1 site in Miami

Sponsor: University of Miami

Sex: Female·Age: 40+

Code: NCT07799467

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

2 sites incl. Boston

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07137416·Phase 1

Apply to this trial

A Phase II Study of Zongertinib Plus Fulvestrant in Participants With HR-positive/HER2-negative Advanced Breast Cancer Harboring HER2 Mutations.

for Advanced Breast Cancer

Sponsor: MedSIR

Sex: All·Age: 18+

Code: NCT07619066·Phase 2

ctDNA-Guided Chemotherapy Omission With Ribociclib Plus Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer

for Breast Cancer

Sponsor: Fudan University

Sex: Female·Age: 18 - 70

Code: NCT07423611·Phase 2

Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast Cancers

for Breast Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07553390·Phase 1

Ultrasound-Guided Core Needle Biopsy to Assess Sensitivity and Specificity of Axillary Lymph Node Metastasis in Breast Cancer

for Lymphatic Metastasis

Sponsor: The First Hospital of Jilin University

Sex: Female·Age: 18 - 70

Code: NCT07573657

An Open-Label, Randomized Phase III Study of Trastuzumab Rezetecan With or Without Bevacizumab in First to Third Line BLIS Subtype TNBC

for Breast Cancer

Sponsor: Fudan University

Sex: Female·Age: 18 - 70

Code: NCT07669610·Phase 3

CRYO-TOUCH: Cryoablation of the Primary Breast Tumor in Metastatic Breast Cancer

for Metastatic Breast Cancer

Sponsor: Hospices Civils de Lyon

Sex: Female·Age: 18+

Code: NCT07676344

Fulvestaciclib Combined With Anti-HER2 and Endocrine Therapy for HR+/HER2+ Advanced Breast Cancer

for Breast Cancer

Sponsor: Fudan University

Sex: All·Age: 18+

Code: NCT07716046·Phase 2

An Open-Label, Randomized Phase III Study of Trastuzumab Rezetecan With or Without Everolimus in First to Third Line LAR Subtype TNBC

for Breast Cancer

Sponsor: Fudan University

Sex: Female·Age: 18 - 70

Code: NCT07760844·Phase 3

QL1706 Plus Neoadjuvant Endocrine Therapy in HR-Positive/HER2-Negative Breast Cancer With a Poor Response to Neoadjuvant Chemotherapy

for Breast Cancer

Sponsor: Hebei Medical University Fourth Hospital

Sex: Female·Age: 18 - 75

Code: NCT07782840·Phase 2

BRain-AVOidant Proton Craniospinal Irradiation for Leptomeningeal Metastases From Solid Tumor Malignancies

for Leptomeningeal Metastasis

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT07789912·Phase 2

HER2 Vaccine for Locally Advanced Breast Cancer

for Breast Cancer

1 site in Indianapolis

Sponsor: Pravin T.P Kaumaya

Sex: All·Age: 18+

Code: NCT06949410·Phase 1

Apply to this trial

Desloratadine to Prevent Taxane-induced Peripheral Neuropathy in Patients With Breast Cancer

for Breast Cancer

1 site in The Bronx

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT07109817·Phase 2

Apply to this trial

Precision Supplemental Imaging in Women With Dense Breasts

for Breast Cancer

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: Female·Age: 25 - 55·Accepts healthy volunteers

Code: NCT07277738

REstoring Metabolic FLEXibility Through Combined Exercise in Breast Cancer Survivors: A Randomized Controlled Trial.

for Cancer

Sponsor: University of Castilla-La Mancha

Sex: Female·Age: 18 - 70

Code: NCT07405385

Pharmacokinetic Model of Abemaciclib: Correlation With Severe Diarrhea as the Primary Toxicity Endpoint in Patients With Localized Hormone Receptor-positive Breast Cancer

for Abemaciclib

Sponsor: Poitiers University Hospital

Sex: Female·Age: 18+

Code: NCT07490509·Phase 4

Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Aromatase Inhibitor-induced Arthralgia (AIA)

for Breast Cancer

Sponsor: Institut Cancerologie de l'Ouest

Sex: Female·Age: 18+

Code: NCT07575750

BRE-06: Study to Increase Tolerance to Aromatase Inhibitors for Patients With Early-Stage Hormone Receptor Positive Breast Cancer Who Developed Hypoactive Sexual Desire Disorder

for Early-stage Breast Cancer

1 site in Chicago

Sponsor: University of Illinois at Chicago

Sex: Female·Age: 18+

Code: NCT07596212·Phase 1, Phase 2

Study of the TheraBionic P1 Device in Patients With Metastatic Triple Negative Breast Cancer After Progression

for Triple Negative Breast Cancer

1 site in Detroit

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: Female·Age: 22+

Code: NCT07672431

SHIELD: Surveillance of HR+/HER2- : Implementing ESR1m Long-term Monitoring and Detection in 1L aBC

for Advanced Breast Cancer

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07701070

Targeting Aurora A Kinase to Overcome Treatment Resistance in Advanced HR+/HER2+ Breast Cancer

for HR+/HER2+ Breast Cancer

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT07706179·Phase 2

Radiation Therapy and Thymus Function in Young Women With Breast Cancer

for Breast Cancer

1 site in Durham

Sponsor: Duke University

Sex: Female·Age: 18 - 50

Code: NCT07725172

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Breast oncology clinical trials — common questions

Are breast oncology clinical trials free to join?

Yes. Participating in a breast oncology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a breast oncology clinical trial?

Each breast oncology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a breast oncology trial near me?

Use the location controls above. We'll show recruiting breast oncology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many breast oncology trials are recruiting right now?

We're currently tracking roughly 953 recruiting breast oncology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Breast oncology trials by city

Boston, MA Los Angeles, CA Birmingham, AL Duarte, CA San Francisco, CA Chicago, IL Tampa, FL Columbus, OH Gainesville, FL Jacksonville, FL Aurora, CO La Jolla, CA

Conditions in this area

Breast cancer Metastatic breast cancer Triple-negative breast cancer HER2-positive breast cancer HER2-negative breast cancer