E-cigarettes for Harm Reduction in Adults With Asthma

Part of paid clinical trials in Providence, Rhode Island.

Sponsor
Brown University
Study ID
NCT05278065
Status
Completed

Conditions

  • Asthma
  • Cigarette Smoking
  • Electronic Cigarette Use
  • Smoking

Eligibility Criteria

Sex
ALL
Age
21 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Nicotine — OTHER
    Participants will be provided with electronic cigarettes and 5% nicotine e-liquid cartridges for 8 weeks and encouraged at weekly assessments to use the electronic cigarette any time they would normally smoke. Participants will be able to choose commercially available e-liquid flavors (tobacco) at each weekly assessment.

Study Details

Smoking is the main cause of preventable disease and death in the US and impacts respiratory illnesses including COPD and asthma. However, little is known about the effects on smoking and lung health of substituting cigarettes with ENDS in adults with asthma. This project aims to test whether providing ENDS to adults with asthma will lead to substitution of smoking for ENDS, reduced dependence, and improved lung function so such knowledge can inform interventions to reduce the public health burden of tobacco.

Key Dates

Start date
May 1, 2022
Status verified
Nov 2025
Primary completion
Sep 12, 2024
Completion
Sep 12, 2024

Study Design

Enrollment
17 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Electronic cigarette
    Participants in this experimental condition will be provided with a 4th generation electronic cigarette device and disposable cartridges.
  • No Intervention: Smoking As Usual
    Participants in this assessment-only condition will continue smoking as usual.

Primary Outcome Measure

Change in Cigarettes Per Day From Baseline to Week 8 and Week 16 [ Time Frame: Baseline, Week 8, Week 16 ]

Locations (1)

FacilityCityStateZIPSite coordinators
Center for Alcohol and Addiction StudiesProvidenceRhode Island02903-

Find similar trials in Providence, RI

By condition
Asthma
By specialty
PulmonologyLung disease
By research site
Center for Alcohol and Addiction Studies· Providence, RI

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