Lung disease Clinical Trials

Recruiting lung disease studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat lung disease. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting lung disease studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting lung disease trials

Within

PulmoSalud: Multimodal Program for Prehabilitation and Early Home Rehabilitation in Patients With Lung Cancer

for Lung Cancer

Sponsor: FranciscoVeraSerrano

Sex: All·Age: 18+

Code: NCT07478276

Chronic COUGH Management in Interstitial Lung DisEase

for Interstitial Lung Disease

Sponsor: Aveiro University

Sex: All·Age: 18+

Code: NCT06782893

RSV Vaccination to Reduce Recurrent AECOPD

for COPD

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 50+

Code: NCT07508644·Phase 4

Antigen-specific T Cells Against Lung Cancer

for Lung Cancer

Sponsor: Shenzhen Geno-Immune Medical Institute

Sex: All·Age: 18 - 80

Code: NCT03356808·Phase 1, Phase 2

Multinational Observational Study to Describe Diagnostic Stage Shift in Patients With Lung Cancer Using Medical Records

for Lung Cancer

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06842056

Pulmonary Rehabilitation Frequency in COPD Patients

for COPD

Sponsor: Hospital Universitario Fundación Alcorcón

Sex: All·Age: All ages

Code: NCT07575841

Witness Project Lung

for Lung Cancer

1 site in Nutley

Sponsor: Hackensack Meridian Health

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07792824

Pharmacokinetics of CFTR Modulators in Pregnant Individuals and in Postpartum Breastfeeding Mothers

for Cystic Fibrosis

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: Female·Age: 18+

Code: NCT04940533

Efficacy and Safety of Slow Release Dehydroepiandrosterone (DHEA )

for Asthma

Sponsor: Indiana University

Sex: All·Age: 18 - 50

Code: NCT07179952·Phase 2

Dissemination Of Lung Cancer Screening Education Through Tobacco Quitlines

for Lung Cancer

1 site in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT07720141

GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF Registry

for Heart Failure With Preserved Ejection Fraction

Sponsor: Miedziowe Centrum Zdrowia SA

Sex: All·Age: 18+

Code: NCT07787936

SMART-School-based Asthma Therapy

for Asthma in Children

Sponsor: University of Rochester

Sex: All·Age: 6 - 12

Code: NCT06796387

Respiratory Muscle Training in Patients Undergoing Lung Cancer Surgery

for Lung Cancer

Sponsor: Saglik Bilimleri Universitesi

Sex: All·Age: 18 - 70

Code: NCT07499986

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

for Lung Transplant

1 site in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80

Code: NCT06770023·Phase 1

Apply to this trial

The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPD

for Chronic Obstructive Pulmonary Disease

Sponsor: University of Alberta

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT04231760·Phase 1, Phase 2

Effect of add-on Doxofylline on Lung Function in Stable COPD

for Chronic Obstructive Pulmonary Disease

Sponsor: University of Milan

Sex: All·Age: 40+

Code: NCT04238221·Phase 4

Portable Positive Pressure Therapy Device

for COPD

Sponsor: Koronis Biomedical Technologies

Sex: All·Age: 21 - 85

Code: NCT04452851

Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD

for COPD

Sponsor: University of Milan

Sex: All·Age: 40+

Code: NCT05381415

Ginger's Therapeutic Potential in Asthma

for Asthma

1 site in New York

Sponsor: Emily DiMango, MD

Sex: All·Age: 18+

Code: NCT07792395·Phase 2

Prospective Multiomic Analysis in Small-Cell Lung Cancer

for Small Cell Cancer Of The Lung

1 site in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07795411

A Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) in India (MK-7962-037)

for Pulmonary Arterial Hypertension

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07600723·Phase 4

An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial

for Lung Carcinoma

1 site in Seattle

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT07615764

Structured Nursing Intervention for Adults With Poorly Controlled Asthma: A Pilot Study

for Asthma

Sponsor: Hospital San Carlos, Madrid

Sex: All·Age: 18+

Code: NCT07635537

Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

for Pancreas Cancer

1 site in Oklahoma City

Sponsor: University of Oklahoma

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07732686

Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib

for Lung Cancer

1 site in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT07782359·Phase 1

A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe Asthma

for Asthma

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 85

Code: NCT07746687·Phase 2

THERMotherapy Against Persistent Bacterial LUNG Infections

for Lung Diseases, Obstructive

Sponsor: Chronic Obstructive Pulmonary Disease Trial Network, Denmark

Sex: All·Age: 18+

Code: NCT05351242

Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Interstitial Lung Disease

for Interstitial Lung Disease

Sponsor: Shanghai Life Science & Technology

Sex: All·Age: 18+

Code: NCT06534528·Phase 1

Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer

for Lung Cancer

1 site in Durham

Sponsor: Duke University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06636721

Testing the SurVaxM Vaccine for Lung Cancer Prevention

for Lung Carcinoma

4 sites incl. Aurora

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07169617·Phase 2

Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants

for Interstitial Lung Disease

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18 - 80

Code: NCT07443436·Phase 2

Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

9 sites incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 40 - 85

Code: NCT07674745·Phase 2

Feasibility of Noninvasive Trigeminal Nerve Stimulation During Exercise

for COPD

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT07686302

Myocardial Metabolic Flux in Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Sponsor: Imperial College London

Sex: All·Age: 18 - 85

Code: NCT07737522·Phase 2

Asthma Lung Sounds With Wearable Stethoscope

for Asthma

1 site in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 4 - 17

Code: NCT07792330

Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR)

for Chronic Obstructive Pulmonary Disease

Sponsor: Eurofarma Laboratorios S.A.

Sex: All·Age: 40+

Code: NCT06234345·Phase 3

Totally Robotic Versus Surgeon-Assisted Robotic Lung Resection For Early-Stage NSCLC

for Lung Cancer

Sponsor: St. Joseph's Healthcare Hamilton

Sex: All·Age: 18 - 120

Code: NCT06348030

Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate

for Asthma

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07664527·Phase 4

Withdrawal of Prostacyclin Pathway Therapy in Patients With Pulmonary Arterial Hypertension Receiving Sotatercept (WATERLOO)

for Pulmonary Arterial Hypertension

Sponsor: University of Alberta

Sex: All·Age: 18+

Code: NCT07700303

Artificially Intelligent Robot Control

for Asthma in Children

1 site in Miami

Sponsor: University of Miami

Sex: All·Age: 4+

Code: NCT07738016

Self-Help Booklets for Sleep in Adults With Pulmonary Hypertension

for Pulmonary Hypertension

Sponsor: University of Sheffield

Sex: All·Age: 18+

Code: NCT07754981

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass-Substudy

for Pulmonary Arterial Hypertension

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07781709

Blood Cell Count Derived Inflammatory Indexes in Acute Exacerbation of Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

Sponsor: Assiut University

Sex: All·Age: 18+

Code: NCT07783230

Family-centred Pulmonary Rehabilitation to Empower Carers

for Pulmonary Disease, Chronic Obstructive

Sponsor: Aveiro University

Sex: All·Age: 18+

Code: NCT07791147

Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients.

for Elderly

Sponsor: Gustave Roussy, Cancer Campus, Grand Paris

Sex: All·Age: 70+

Code: NCT07802847·Phase 4

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

for Bronchopulmonary Dysplasia

2 sites incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 Month - 5 Months·Accepts healthy volunteers

Code: NCT06373289

Apply to this trial

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

for Lung Carcinoma

2 sites incl. Auburn

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07176000

Apply to this trial

Home-Based Respiratory Muscle Training and Aerobic Exercise Programs to Improve Lung Health in Current and Former Cigarette Smokers

for Lung Carcinoma

1 site in Buffalo

Sponsor: Roswell Park Cancer Institute

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT07553819

A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)

for Asthma

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07645248·Phase 3

CS1 Added to Standard of Care Therapy for Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Sponsor: Cereno Scientific AB

Sex: All·Age: 18 - 80

Code: NCT07761572·Phase 2

A Study of a Side Effects and Resource Navigation Program for People With Cancer

for Kidney Cancer

8 sites incl. Basking Ridge

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07646847

Apply to this trial

A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)

for Chronic Obstructive Pulmonary Disease

Sponsor: Sanofi

Sex: All·Age: 40 - 80

Code: NCT07793409·Phase 3

Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging

for Allogeneic Stem Cell Transplantation

1 site in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 100

Code: NCT07613099·Phase 3

Apply to this trial

Pulmonary Hypertension (PH) Biorepository for Translational Research

for Pulmonary Hypertension

3 sites incl. Baltimore

Sponsor: National Institutes of Health Clinical Center (CC)

Sex: All·Age: 18 - 100

Code: NCT07647549

Vapor Ablation for Localized Cancer Lesions

for Non Small Cell Lung Cancer

Sponsor: Uptake Medical Technology, Inc.

Sex: All·Age: 18+

Code: NCT03514329

Developing an Intervention to Optimize Virtual Care Adoption for COPD Management

for Chronic Obstructive Pulmonary Disease

2 sites incl. Bedford

Sponsor: VA Office of Research and Development

Sex: All·Age: 40+

Code: NCT05986214

Clinical Trial of 2-HOBA in Pulmonary Arterial Hypertension

for Pulmonary Arterial Hypertension

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06176118·Phase 2

Combinaison of Virtual Reality and Rehabilitation to Improve Muscle Function, Exercise Tolerance, Exertional Symptoms and Dyspnea in Patients With Chronic Respiratory Disease: a Randomized Cross-over Trial

for Chronic Obstructive Pulmonary Disease

Sponsor: Fondation Hôpital Saint-Joseph

Sex: All·Age: 18+

Code: NCT06811402

A New Way to Share Radiation Therapy Plans Between Doctors, CORRECT Trial

for Lung Carcinoma

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07282444

Immuno-inflammatory Response of Erdosteine in COPD

for COPD

Sponsor: Pierachille Santus, MD, PhD

Sex: All·Age: 45+

Code: NCT07329946

New trials in Birmingham, AL?

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Lung disease clinical trials — common questions

Are lung disease clinical trials free to join?

Yes. Participating in a lung disease clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a lung disease clinical trial?

Each lung disease study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a lung disease trial near me?

Use the location controls above. We'll show recruiting lung disease trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many lung disease trials are recruiting right now?

We're currently tracking roughly 561 recruiting lung disease trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Lung disease trials by city

Birmingham, AL Boston, MA Aurora, CO Los Angeles, CA Chicago, IL Cincinnati, OH Denver, CO Palo Alto, CA San Francisco, CA Seattle, WA Stanford, CA Cleveland, OH

Conditions in this area

Asthma COPD Cystic fibrosis Interstitial lung disease Idiopathic pulmonary fibrosis Pulmonary hypertension Lung cancer